Clinical trials
Advanced clinical trials
Below are recruiting advanced clinical trials, each written for real people, not researchers. We’re tracking 3,897 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06946745Recruiting
Studying IBI363 combo for advanced colorectal cancer
This study tests a new combination therapy (IBI363 with other drugs) for advanced colorectal cancer that is pMMR/MSI-L/MSS. It aims to understand how the immune system around the tumor changes during treatment.
BeijingAges 18–75 - NCT07188311Recruiting
Study of pucotenlimab with lenvatinib and chemo for relapsed hepatoblastoma in children
This trial tests a combination of an immunotherapy (pucotenlimab), a targeted therapy (lenvatinib), and chemotherapy for children with advanced or relapsed hepatoblastoma that hasn't responded to prior treatment. The goal is to see if this combination can help shrink or control the tumor.
Guangdong, GuangzhouAges 2–18 - NCT07192185RecruitingPhase 2
Chemo plus immunotherapy for advanced liver cancer after first treatment fails
This trial tests a new combination of chemotherapy (FOLFOX) plus atezolizumab and bevacizumab for people with advanced liver cancer that has grown after having atezolizumab and bevacizumab alone. The goal is to see if adding chemo helps stop the cancer from growing further.
Guangzhou, GuangdongAges 18–75 - NCT07186218Recruiting
Symptom monitoring with feedback for advanced kidney disease
This study tests a symptom-monitoring system with feedback for people with advanced chronic kidney disease (CKD). The goal is to help manage symptoms and improve quality of life without needing dialysis or a transplant right away.
Boston, MassachusettsAges 18 years+ - NCT07186725Recruiting
Home sleep monitor for obstructive sleep apnea
This trial tests a new home-based sleep monitor that goes under your mattress. It may help people with obstructive sleep apnea who are using a mouthpiece (MAD) as treatment.
Lexington, KentuckyAges 18–80 - NCT06946771Recruiting
MRI and prostate lesions: understanding diagnosis and prognosis
This trial uses MRI scans to study prostate lesions and see how they relate to diagnosis, pathology, and long-term outcomes. It may help patients with concerns about prostate health get more detailed imaging.
Wuhan, HubeiAges 18 years+ - NCT06946615RecruitingPhase 1
Claudin18.2 cell therapy for advanced colorectal cancer
This study tests a new treatment using your own immune cells (called CAR-T and CAR-DC) that are engineered to attack cancer cells with a specific protein (Claudin18.2). It is for people with advanced colorectal cancer who have exhausted standard treatments.
Hangzhou, ZhejiangAges 18–70 - NCT05965531RecruitingPhase 2
TAS-102 plus radiation before surgery for rectal cancer
This trial studies whether adding TAS-102 (a chemotherapy medicine) to radiation given before treatment improves outcomes for certain locally advanced rectal cancers. It may help by trying to shrink the tumor before the next steps of care.
Guangzhou, GuangdongAges 18–70 - NCT05201404RecruitingPhase 3
Namodenoson for advanced liver cancer with moderate cirrhosis
This Phase 3 trial studies whether namodenoson can slow or control advanced hepatocellular carcinoma (liver cancer) in people whose cirrhosis is in a specific middle range. It may help if standard treatments have not worked or the cancer has spread and is not expected to be cured.
Dallas, TexasAges 18 years+ - NCT07179757Recruiting
Vulvovaginal cancer treatment study
This study looks at how well treatments like radiation, chemotherapy, or surgery work for people with vulvar or vaginal cancer, and how they affect quality of life. It includes patients treated between 2019 and 2023.
Mumbai, MaharashtraAges Any age - NCT06944444RecruitingPhase 1
Testing a new drug for advanced tumors
This trial tests a new drug, SSS59, in people with advanced solid tumors that have not responded to other treatments. It aims to see if the drug is safe and how it affects the body.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07176234Enrolling by invitation
Linking exercise for better stress management in teens
This study tests whether a home-based exercise program can help African American teens (ages 11–16) manage daily stress. It compares the program to a healthy lifestyle education group.
Columbia, South CarolinaAges 11–16 - NCT07174947RecruitingPhase 2
Fluoxetine plus immunotherapy for advanced liver cancer with depression
This study tests whether adding the antidepressant fluoxetine (Prozac) to standard immunotherapy can help treat advanced liver or bile duct cancer in people who also have depression or anxiety. You must not have received any prior cancer treatment and be ready to start immunotherapy as your first therapy.
Wenzhou, ZhejiangAges 18–80 - NCT07182357Recruiting
Improving hospice transitions for advanced dementia
This study looks at how to improve the transition to hospice care for people with advanced dementia and their care partners. It will interview care partners and healthcare professionals to design better care management.
New York, New YorkAges 18 years+ - NCT07177443RecruitingPhase 3
Immunotherapy with chemo and radiation for nasopharyngeal cancer
This trial tests a new immunotherapy drug (serplulimab) given together with standard chemotherapy and radiation for nasopharyngeal cancer that has spread to nearby lymph nodes. It aims to see if adding this drug can help shrink tumors and improve outcomes.
Wuhan, HubeiAges 18–65 - NCT07183150Recruiting
Lymph node removal range for advanced stomach cancer
This study is looking at how far surgeons should remove lymph nodes during surgery for advanced stomach cancer. It may help doctors decide the best way to remove cancer while reducing side effects.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT07182721RecruitingPhase 2
Study of SKB264 plus Inetetamab for advanced HER2+ breast cancer after T-DXd
This trial is testing a combination of two targeted therapies, SKB264 and Inetetamab, for people with advanced HER2-positive breast cancer that has kept growing after treatment with T-DXd and other HER2-targeted therapies. The goal is to see if this new combination can shrink tumors or slow the cancer's growth.
ShanghaiAges 18 years+ - NCT07178028Enrolling by invitation
Balance check: in-person vs. video for older adults
This study compares in-person balance assessments with video-based (telehealth) assessments for older adults. It aims to see if balance can be checked reliably over a video call, making it easier for you to participate from home.
Istanbul, BüyükçekmeceAges 65 years+ - NCT07179484Recruiting
Study of CT041 for advanced stomach or junction cancer after first treatment
This trial tests a new cell therapy (CT041) for people with advanced stomach or gastroesophageal junction cancer that has a specific marker called CLDN18.2. It is given after initial chemotherapy to try to keep the cancer from growing.
BeijingAges 18–75 - NCT07178054Recruiting
Measuring daily energy use in healthy Chinese adults
This study measures how much energy healthy people across China use each day by using a special water test. It helps researchers understand normal energy needs for different populations.
Chongqing, Chongqing MunicipalityAges 7–60 - NCT07182149RecruitingPhase 1
Testing a new drug for advanced solid tumors
This trial tests a new drug called NRM-823 for people with several types of advanced cancer that have stopped responding to standard treatments. The goal is to see if the drug is safe and how well it works.
Denver, ColoradoAges 18 years+ - NCT07178795RecruitingPhase 3
New drug vs standard care for HER2-mutant lung cancer
This study is testing a new drug (BL-M07D1) compared to a standard combination of pembrolizumab and chemotherapy for people with a specific type of advanced lung cancer (non-squamous NSCLC) that has a HER2 mutation and has not been treated before. The goal is to see which treatment works better.
Guangzhou, GuangdongAges 18–75 - NCT07175220RecruitingPhase 2
Study of SHR2554 tablets combined with other treatments for lung cancer
This trial tests a new drug combination for people with non-small cell lung cancer that has spread or cannot be removed by surgery. It aims to see if adding SHR2554 tablets to other anticancer treatments can help control the disease.
Guangzhou, GuangdongAges 18–75 - NCT07179692RecruitingPhase 1
CEA-targeted CAR-T therapy for advanced solid tumors
This trial tests a type of immunotherapy called CAR-T, which is designed to recognize and attack cancer cells that have a protein called CEA on their surface. It's for people with advanced cancers like colorectal, esophageal, gastric, pancreatic, lung, or bile duct cancer who have tried at least two standard treatments.
Hefei, AnhuiAges 18 years+
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Common questions
- Are there clinical trials for advanced?
- Yes. Clin2 currently lists 3,897 recruiting advanced studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.