Clinical trials
Aged 65 Years or Older clinical trials
Below are recruiting aged 65 years or older clinical trials, each written for real people, not researchers. We’re tracking 1,068 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05516277Recruiting
Insomnia care study for older adults with PTSD
This study tests a treatment plan for insomnia (trouble sleeping) in older adults who also have post-traumatic stress disorder (PTSD). The goal is to see whether improving sleep also supports heart and metabolic health (such as blood sugar and heart-related measures).
North Hills, CaliforniaAges 50 years+ - NCT05524597RecruitingPhase 1
Older adults write about health experiences
This study looks at how writing about your life experiences and health affects outcomes in older adults. If you’re 65 or older and meet health and safety requirements, you may be able to take part.
Los Angeles, CaliforniaAges 65 years+ - NCT05525663Recruiting
Rehab for older adults after heart failure with strong pumping
This trial studies whether a physical rehabilitation program helps older adults recover and function better after a recent hospital stay for heart failure when the heart’s pumping strength is preserved. It may help you regain walking ability and daily independence after your episode.
Winston-Salem, North CarolinaAges 60 years+ - NCT05486884Recruiting
Blood pressure goal after out-of-hospital cardiac arrest
This study looks at whether targeting a specific blood pressure after a cardiac arrest can improve outcomes. It is mainly for people who are in intensive care and need a breathing machine because they are in a deep coma.
Montpellier, SartheAges 18 years+ - NCT05465538RecruitingPhase 1/Phase 2
PET imaging study using SV2A in older adults
This early-phase study tests a PET scan tracer called SV2A in adults age 50 and older. It aims to help researchers understand how the tracer works in the brain/body, which could support future diagnostic or treatment research.
New Haven, ConnecticutAges 50 years+ - NCT05461092RecruitingEarly Phase 1
Nerve blocks to improve pain control after spinal fusion
This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.
Iowa City, IowaAges 65 years+ - NCT05497024Recruiting
Decision aid testing for older men on prostate cancer surveillance
This trial tests an English decision aid (a patient guide) to help older men understand and feel comfortable with “active surveillance” for localized prostate cancer. It also checks how easy to use it is for patients, caregivers, and prostate cancer clinicians.
Houston, TexasAges 65 years+ - NCT05484739Recruiting
Testing cooling methods for heat waves in older adults
This study looks at how different cooling methods affect older adults during heat waves. It may help identify safer ways to reduce heat-related stress for people at risk.
Dallas, TexasAges 65 years+ - NCT05448547RecruitingPhase 3
Tested curative vs conservative treatment for older men with high-risk prostate cancer
This Phase 3 study compares an immediate curative treatment plan versus a more conservative approach in men age 75 and older with newly diagnosed, high-risk prostate cancer. The goal is to see which strategy controls the cancer while better protecting quality of life.
CopenhagenAges 75 years+ - NCT05388214Recruiting
Exercise and memory rehab for older cancer survivors
This trial tests whether a supervised exercise and brain-training program can improve memory and thinking skills in older people after cancer treatment. It may help if you’re noticing thinking or memory problems since finishing curative cancer care.
Rochester, New YorkAges 60 years+ - NCT05372172Recruiting
Tennessee Alzheimer’s study for people 60 and older
This study is looking at how brain and memory changes show up in people across the Alzheimer’s spectrum—from normal thinking to mild memory problems to Alzheimer’s disease. You might join if you can do study visits and an MRI and have a reliable study partner available.
Nashville, TennesseeAges 60 years+ - NCT05355415Recruiting
Eye imaging study for outer retina diseases using adaptive optics
This study uses a special, high-detail eye imaging machine to take clear pictures of the outer retina. It may help researchers understand these eye conditions better, and how the eye images look when people have an outer retinal disease.
Bethesda, MarylandAges 21 years+ - NCT05336565Recruiting
COVID-era heart illness patterns in adults with cardiovascular disease
This study looks at how often heart problems happened in adults with cardiovascular disease during the COVID-19 pandemic period. It may help researchers understand what factors during the pandemic affected heart health.
TomskAges 18 years+ - NCT05237570Recruiting
Less invasive sinus lift for upper back teeth
This trial tests a minimally invasive procedure to lift the sinus floor to help support an upper back tooth area when the tooth cannot be rebuilt. It may help people who need bone support for a future dental restoration or implant by using a specific, less invasive pathway.
MurciaAges 18 years+ - NCT05246813Recruiting
Study blood cell changes in older adults
This study looks at how blood-forming stem cells change in people with clonal hematopoiesis (CHIP), a common age-related blood condition. It may help researchers understand what these changes mean and who might be at higher risk for future blood problems.
Bonheiden, BelgiëAges 55 years+ - NCT05145400RecruitingPhase 2
Drug treatment for frail or older newly diagnosed multiple myeloma
This Phase 2 study tests whether “isa-Rd” can safely and effectively treat people who have newly diagnosed multiple myeloma and are frail or much older. It may help those who are at higher risk of side effects from stronger, full-intensity chemotherapy.
Chapel Hill, North CarolinaAges 18 years+ - NCT05176561Enrolling by invitation
Brain and hearing training for older cochlear-implant users
This trial studies whether a structured auditory (hearing) and cognitive (thinking) training program can improve outcomes for adults who use cochlear implants. It’s designed for people at a certain stage after their implant and with specific hearing and thinking test results.
Washington D.C., District of ColumbiaAges 60 years+ - NCT05107947Recruiting
Dynamic room lighting to improve sleep and daily body rhythm
This study tests whether changing the light in a hospital room can improve sleep and help your body clock work better in older adults. It may be most helpful if sleep problems or irregular daily rhythms are affecting you in the hospital.
MalmöAges 65 years+ - NCT05081596Recruiting
Primary care program for mood and thinking in early Alzheimer’s
This trial tests a psychosocial (talk/behavior/support) program delivered through primary care to improve thinking and depression symptoms in older adults with mild cognitive problems and early Alzheimer’s. It may help if you have early memory/thinking changes plus mild depressive symptoms and you can work with a caregiver or study partner.
White Plains, New YorkAges 60 years+ - NCT05006482RecruitingPhase 3
Geriatric education and care support for older cancer survivors
This study tests whether a structured health education and “older adult care” approach—done with your oncology team—can improve support for people after cancer. It includes older cancer survivors and a chosen caregiver, using in-person or video visits for follow-up.
Tuscaloosa, AlabamaAges 18 years+ - NCT05000515Recruiting
Breathing muscle training to lower blood pressure in postmenopause
This study compares a breathing-based exercise program with regular aerobic exercise to help lower blood pressure and improve blood vessel function in postmenopausal women. It’s mainly for people with mildly elevated resting blood pressure who are not already doing very intense workouts.
Boulder, ColoradoAges 50 years+ - NCT04959175RecruitingPhase 1/Phase 2
Lower-dose transplant drug for older or frail patients with blood cancer
This study tests whether a lower dose of a drug used after bone marrow transplant can reduce side effects while still preventing graft-versus-host disease (a condition where donor cells attack the patient's body). It is for older patients or those who are not healthy enough for a standard, stronger conditioning regimen.
Bethesda, MarylandAges 12–85 - NCT04938349Recruiting
Dual-task training for memory and balance in older adults
This trial tests a type of training that challenges you to do two tasks at once to help with thinking and movement. It is for people over 55 who may have mild memory problems but do not have major brain, heart, or lung conditions.
Chicago, IllinoisAges 55 years+ - NCT04981821Recruiting
Mobile exercise coaching for older adults with blood cancers
This study tests whether a mobile (phone-based) exercise program can help older adults with myeloid blood cancers stay active and function better while they receive outpatient cancer treatment. You may be asked to follow an exercise plan and participate in assessments during the trial.
Rochester, New YorkAges 60 years+
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Common questions
- Are there clinical trials for aged 65 years or older?
- Yes. Clin2 currently lists 1,068 recruiting aged 65 years or older studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aged 65 years or older trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aged 65 years or older trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.