Clinical trials
Aged 65 Years or Older clinical trials
Below are recruiting aged 65 years or older clinical trials, each written for real people, not researchers. We’re tracking 1,068 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05910619Recruiting
Noninvasive brain stimulation to support memory and thinking
This study tests a noninvasive way of stimulating the brain to see if it can help older adults with typical age-related changes or mild memory problems. You may be invited if your screening tests and health history fit one of their target groups.
Gainesville, FloridaAges 65–84 - NCT05906511RecruitingEarly Phase 1
Study how THC levels change in older adults
This early study measures how a THC dose (by mouth or vaporized form) moves through the body and how it affects the body’s responses. It mainly looks at safety and how THC behaves in older adults, including people who have used cannabis before.
West Haven, ConnecticutAges 65 years+ - NCT05851898RecruitingPhase 4
Tested medicine to prevent depression after hip or leg fractures
This trial studies whether a type of antidepressant medicine (a serotonin–norepinephrine reuptake inhibitor) can prevent depression after a lower-extremity fragility fracture that was treated with surgery. It’s mainly for older adults, and aims to see if starting this medicine early reduces later depression symptoms.
Winston-Salem, North CarolinaAges 65 years+ - NCT05822466Recruiting
Virtual Tai Chi program to help prevent falls
This study tests whether a virtual (online) Tai Chi–style exercise program can reduce falls in older adults. You may be eligible if you’ve fallen recently or have a mobility test result that suggests a higher fall risk.
Springfield, OregonAges 65–90 - NCT05820841RecruitingPhase 3
Acalabrutinib plus R-miniCHOP for untreated lymphoma in older adults
This study tests whether adding acalabrutinib to a reduced-strength chemotherapy plan (R-miniCHOP) works better and is safer for older adults with newly diagnosed diffuse large B-cell lymphoma. It may help you get a more effective treatment while using a dosing approach meant for people who may not tolerate full-strength therapy.
Homburg, SaarlandAges 61 years+ - NCT05830942Recruiting
Training walks plus brain stimulation for thinking skills in older adults
This study tests whether a structured walking exercise, combined with brain stimulation and brain scans, can improve or slow decline in thinking skills. It’s aimed at older adults who notice memory or confusion getting worse.
Gainesville, FloridaAges 65 years+ - NCT05808543Recruiting
BEARS training to improve hearing skills in teens with two implants
This study tests a structured training program (BEARS) designed to help children and teenagers who use cochlear implants in both ears hear better in everyday life. It aims to improve hearing abilities by building on your implant settings and usual care.
Birmingham, BirminghamAges 8–16 - NCT05786417RecruitingPhase 4
Medication comparison for older adults with stable heart pain
This trial tests which heart medications work best for older adults who have stable angina (predictable chest pain) and multiple other long-term health problems. You may be asked to start or adjust medications and attend regular follow-up visits to see which approach controls symptoms and outcomes.
New Haven, ConnecticutAges 65 years+ - NCT05788666Recruiting
GeriKit check-up for older adults after heart artery problems
This trial tests a “GeriKit” set of questions and measurements to better understand health and needs in people age 75+ after a heart attack or related procedures. It may help doctors plan more personalized care during recovery.
New York, New YorkAges 75–100 - NCT05770479Enrolling by invitation
Testing long-lasting cognitive training for older veterans
This study looks at whether a cognitive training program you’ve already completed can keep helping over time, and whether it can be improved with “booster” sessions. It may help older veterans maintain thinking and daily functioning skills after earlier training.
San Diego, CaliforniaAges 55 years+ - NCT05761860RecruitingEarly Phase 1
Oxytocin to lower opioid misuse risk and pain in older adults
This early-phase study tests whether oxytocin (a hormone-like medication) can reduce how “appealing” opioids feel and also reduce pain. It’s aimed at older adults who have used opioids before but are not currently dealing with chronic pain most days.
Gainesville, FloridaAges 45–85 - NCT05762796Recruiting
Brain scan and stimulation study for kids with mild concussion
This study tests whether a brain “stimulation” approach, paired with brain imaging (MRI), can help children who still have symptoms after a mild concussion. There is also a comparison group of children without concussion history.
Buffalo, New YorkAges 10–15 - NCT05725928Recruiting
Walking-support program for older hospitalized patients
This study tests whether extra help and guidance to walk while you’re in the hospital can improve health and recovery. It’s for older adults who can safely do some walking after being admitted for a medical problem.
Springfield, MassachusettsAges 65 years+ - NCT05743517Recruiting
Exercise program for older women with gynecologic cancer
This trial tests a physical activity (exercise) program for women over 60 who are being treated for cancers of the uterus, ovaries, cervix, or vulva/vagina. It may help improve strength and daily functioning during treatment.
Chicago, IllinoisAges 60 years+ - NCT05392582Recruiting
Study tiny gene signals to calm inflammation with aging
This trial studies tiny gene-like signals (microRNAs) to understand and reduce long-term inflammation as people get older. It may help researchers learn how aging affects inflammation and could guide future treatments.
Salt Lake City, UtahAges 18 years+ - NCT05676944Recruiting
Cochlear-like implant to help balance in older adults
This study tests a surgically placed implant aimed at improving balance and eye-stabilizing reflexes in older adults who have long-lasting, hard-to-treat inner-ear balance problems. You may be able to help researchers learn whether the device plus training can reduce dizziness and improve movement stability.
Baltimore, MarylandAges 65–90 - NCT05700058Recruiting
Testing how different Super-whey doses affect muscle growth
This study checks how different doses of “Super-whey” influence muscle protein building in adults. It may help figure out the best whey dose for building muscle, especially in older adults.
DerbyAges 65–85 - NCT05653258RecruitingPhase 2/Phase 3
Study cells in fat tissue and aging cells in older adults
This study uses a special lab test on tiny samples from body fat to map different cell types and “senescent” (aging) cells. It may help researchers understand how aging and obesity are linked, which could guide future treatments.
Los Angeles, CaliforniaAges 18 years+ - NCT05642884Recruiting
Pre-surgery program for older adults getting stem cell transplant
This study checks whether a “pre-surgery” health coaching program is practical and safe for older people with multiple myeloma who are scheduled for an autologous stem cell transplant. It may help patients prepare better for transplant recovery, and the study will see if the plan can be carried out smoothly.
Birmingham, AlabamaAges 60 years+ - NCT05625204Recruiting
HIIT exercise program to improve frailty in older veterans
This trial tests a high-intensity interval training (HIIT) exercise program to help older veterans feel stronger and more resilient and to reduce frailty. It may help people who are not yet very frail (or are just starting to become frail) but can safely exercise.
Kansas City, MissouriAges 65 years+ - NCT05612347Recruiting
Compare stool test vs colonoscopy for older adults with polyps
This study compares two ways to check for colon polyps in older adults: using a stool test versus having a colonoscopy. It may help find a simpler option if you only had a small number of lower-risk polyps before.
Birmingham, AlabamaAges 65–82 - NCT05619731Recruiting
Telehealth geriatric care for older adults with cancer
This trial checks whether video visits (teleconsulting) that include a “geriatric oncology” assessment can better support older adults with cancer. It may help your care plan by considering age-related health needs, not just cancer treatment.
AvignonAges 75 years+ - NCT05612789Recruiting
Exercise coaching for older patients before and after transplant
This trial studies whether an exercise program (“prehab” before transplant and “rehab” after) can improve outcomes for people age 60+ getting an allogeneic stem cell transplant for blood cancer. It focuses on fitness and recovery, especially for those who are pre-frail or frail.
Philadelphia, PennsylvaniaAges 60 years+ - NCT05574127Recruiting
Brief behavioral therapy for depression in older cancer survivors
This study tests a brief behavioral activation program to help older cancer survivors with depression. It involves 10 sessions (or a shorter version) to improve mood and quality of life.
New York, New YorkAges 65 years+
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Common questions
- Are there clinical trials for aged 65 years or older?
- Yes. Clin2 currently lists 1,068 recruiting aged 65 years or older studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aged 65 years or older trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aged 65 years or older trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.