Clinical trials
Alcohol Use Disorder clinical trials
Below are recruiting alcohol use disorder clinical trials, each written for real people, not researchers. We’re tracking 356 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04811014RecruitingPhase 4
Helping young adults stop opioids after an emergency visit
This study offers an engagement program for young people who tested positive for opioids and meet criteria for opioid dependence. The goal is to help participants stop opioid use safely and learn whether this approach works well in the real-world emergency setting.
Houston, TexasAges 13–17 - NCT06107062RecruitingPhase 2
CBD treatment for cannabis concentrate users
This trial tests CBD as a potential treatment for heavy cannabis concentrate users who want to cut down or quit. You would take CBD daily and attend regular visits to track your progress.
Boulder, ColoradoAges 21 years+ - NCT06067737RecruitingPhase 2
Psilocybin and buprenorphine for opioid use disorder
This study tests whether adding psilocybin (a psychedelic medicine) to buprenorphine (a medication for opioid use disorder) can help people stop using opioids and stay in recovery. It is for people who have already been on buprenorphine but are still using other opioids.
Baltimore, MarylandAges 21–70 - NCT05452772RecruitingPhase 2
Psilocybin plus niacin to help quit smoking
This Phase 2 study tests whether a psilocybin “session” with niacin can help people quit smoking. It’s for adults who smoke daily and want to quit but have tried and struggled before.
Birmingham, AlabamaAges 21 years+ - NCT05450718RecruitingPhase 4
Low-dose buprenorphine start for opioid use disorder
This trial tests whether starting buprenorphine using a low-dose plan is a safe and workable way to treat opioid use disorder. You may be able to join if you are 18+, have opioid use disorder, and can follow the study medication and visits.
The Bronx, New YorkAges 18 years+ - NCT05011760RecruitingEarly Phase 1
PET brain scan with a cocaine-use disorder medicine test
This early-phase study uses a PET brain scan (a special imaging test) to see how the brain responds in people with cocaine use disorder. It aims to better understand brain activity and whether this scan approach could help research or future treatments.
Pittsburgh, PennsylvaniaAges 18–55 - NCT05860699RecruitingPhase 2
Cannabidiol added during inpatient alcohol withdrawal
This trial tests whether cannabidiol (CBD) given during an inpatient alcohol detox helps people stay off alcohol afterward. You would be compared with standard care to see if CBD improves recovery during and after withdrawal.
Créteil, Albert ChenevierAges 18–75 - NCT03470480Recruiting
Brain stimulation for methamphetamine cravings
This study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can help reduce cravings for methamphetamine in people who have stopped using it for at least 4 weeks. If you are trying to stay off methamphetamine and struggling with cravings, this treatment might help.
Portland, OregonAges 18–65 - NCT07684976Recruiting
Safety of a helmet device using ultrasound for substance use disorder
This study tests a special helmet that uses focused ultrasound to stimulate parts of the brain involved in addiction. It aims to see if the treatment is safe and works for people with moderate to severe substance use disorder who have not gotten enough help from standard medication treatments.
Toronto, OntarioAges 18–70 - NCT06796062RecruitingPhase 2
Psilocybin for opioid use disorder
This study tests whether psilocybin can help people who want to stop using opioids and are already in treatment. Eligible participants receive a single dose of psilocybin in a supervised setting and are followed to see if it reduces opioid use.
Albuquerque, New MexicoAges 18–65 - NCT06286774Recruiting
Sleep and alcohol treatment study
This study tests whether improving sleep through cognitive behavioral therapy (CBT-I) can help reduce heavy drinking in people with both alcohol use disorder and insomnia. It might be a good fit if you have trouble sleeping and drink heavily.
Columbia, MissouriAges 18–49 - NCT06160284RecruitingPhase 1
Psilocybin for brain healing in opioid recovery
This study tests whether psilocybin, a psychedelic substance, can help change brain connections in people recovering from opioid use disorder. It involves brain scans and careful medical monitoring to explore new treatment options.
New Haven, ConnecticutAges 25–55 - NCT05934305Recruiting
Help for shame and stigma in HIV and substance use
This study tests whether a program can reduce shame and stigma for people living with HIV who also have a substance use disorder. It may help you feel less judged and cope better, while supporting HIV care.
Miami, FloridaAges 18 years+ - NCT05163301Recruiting
Alcohol relapse prevention for adults living with HIV
This study looks at ways to help people with HIV reduce the chance of heavy drinking coming back after a period of lower-risk drinking. It will use regular patient-reported check-ins about alcohol use to understand relapse patterns and test the approach’s impact.
Baltimore, MarylandAges 18 years+ - NCT05011266RecruitingPhase 2/Phase 3
Buprenorphine plus naltrexone shot to prevent opioid relapse
This trial tests whether a combination of buprenorphine (through your care plan) and a monthly extended-release naltrexone (XR-NTX) shot can help prevent opioid relapse. It may help people who are ready to move toward a naltrexone-based relapse-prevention treatment after detox.
Rockville, MarylandAges 18–65 - NCT06486688Recruiting
Virtual program to help teens with substance use risk
This trial tests a virtual program integrated into pediatric check-ups to help teens at risk for alcohol or drug problems. It aims to identify teens who may need extra support and connect them with helpful resources.
Pleasanton, CaliforniaAges 12–17 - NCT06323837RecruitingPhase 2
Testing mirtazapine for methamphetamine use in people on opioid treatment
This trial tests whether the antidepressant mirtazapine can help reduce methamphetamine use in people who are already receiving medication for opioid use disorder. It aims to see if adding this medication improves outcomes for those struggling with both conditions.
Spokane, WashingtonAges 18 years+ - NCT07713251Recruiting
Computer skills training for teens seeking alcohol help
This study tests a computer-based program called Path180 to help teenagers ages 13-19 reduce their alcohol use. If you are already seeing a counselor or in treatment for alcohol or mental health, this program might add extra support.
Providence, Rhode IslandAges 13–19 - NCT07079826Recruiting
Sparrow Link device for opioid withdrawal in hospital
This trial tests a device placed on the ear to help manage opioid withdrawal symptoms in hospitalized adults. It's for people still having withdrawal despite standard medications or those who've chosen not to take methadone or buprenorphine.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07059078Recruiting
Talk therapy with or without mindfulness for teen drinking
This study tests whether a brief talk therapy session, sometimes combined with mindfulness exercises, can help teens reduce alcohol use. It is designed for teens who get care at Johns Hopkins and already drink alcohol at least once a month.
Baltimore, MarylandAges 12–17 - NCT07027839RecruitingPhase 1
Alcohol effects on brain imaging for phosphodiesterase
This study uses PET scans to see how alcohol affects a protein in the brain called PDE4B. It may help explain how alcohol works in the body.
Bethesda, MarylandAges 21–70 - NCT05800899Recruiting
Brief counseling program for alcohol-related injuries in Latinxs
This trial tests a culturally tailored, short counseling session for people who are Latinx and have alcohol-related injuries. It aims to reduce health disparities by helping improve treatment access and outcomes after an injury.
El Paso, TexasAges 18 years+ - NCT06585709Recruiting
Brain stimulation for opioid use disorder treatment
This trial tests if brain stimulation can help people starting buprenorphine for opioid use disorder. It aims to improve treatment outcomes and support recovery.
Durham, North CarolinaAges 18 years+ - NCT06838468Enrolling by invitation
Study on liver health in alcohol detox patients
This study is looking at liver health in people staying in a detox unit for alcohol use disorder. Researchers want to see how common liver problems are in this group. Participating involves extra tests like blood work, an ultrasound, and a special liver scan (FibroScan).
Sabadell, BarcelonaAges 18–75
Hear when a new Alcohol Use Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for alcohol use disorder?
- Yes. Clin2 currently lists 356 recruiting alcohol use disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alcohol use disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alcohol use disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.