Clinical trials
Alcohol clinical trials
Below are recruiting alcohol clinical trials, each written for real people, not researchers. We’re tracking 527 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05490589Recruiting
Parenting program for parents affected by alcohol use
This trial tests a structured parenting program for parents of children ages 4 to 12 when the parent (or spouse) has an alcohol use disorder. It may help families by supporting parenting skills and improving day-to-day family functioning.
BrestAges 18 years+ - NCT05463796Recruiting
Prevention and early detection for people at high cancer risk
This study looks at surveillance (watching closely), prevention, and early “interception” steps to lower the chance that cancer will develop or be found later. It is for people with genetic risk, past cancer treatment exposures, strong family history, or certain early pre-cancer or high-risk conditions.
Boston, MassachusettsAges Any age - NCT05486234Recruiting
Study to reduce cannabis and alcohol use with teen and caregiver
This study looks at ways to help teens cut down on cannabis and alcohol use. You may qualify if you’ve been using both in the last three months and your caregiver is able to join and consent.
Charleston, South CarolinaAges 13–17 - NCT05418244RecruitingPhase 2/Phase 3
Inhaled isopropyl alcohol for nausea and vomiting relief
This trial tests whether breathing in a small amount of isopropyl alcohol through the nose can reduce nausea or vomiting. It may help people who still have bothersome nausea even with usual care, by using a non-oral approach to start feeling better.
Buffalo, New YorkAges 7–17 - NCT05288790RecruitingPhase 2
Study how gut chemicals and alcohol affect heart risk in HIV
This Phase 2 study looks at how “microbiome metabolites” (chemicals from gut bacteria) and alcohol may affect heart and blood vessel risk in people living with HIV. If you qualify, you may be asked to follow a study plan to see how these factors change health markers related to cardiovascular disease.
Nashville, TennesseeAges 18–89 - NCT05163301Recruiting
Alcohol relapse prevention for adults living with HIV
This study looks at ways to help people with HIV reduce the chance of heavy drinking coming back after a period of lower-risk drinking. It will use regular patient-reported check-ins about alcohol use to understand relapse patterns and test the approach’s impact.
Baltimore, MarylandAges 18 years+ - NCT05181891RecruitingPhase 2
Trial uses enhanced cues to reduce alcohol and smoking
This Phase 2 study tests a program designed to help people cut down or stop heavy alcohol use and daily smoking at the same time. It will check your alcohol level at the start and uses urine tests during a short induction phase to confirm recent alcohol and ongoing smoking.
Spokane, WashingtonAges 18 years+ - NCT05093881Recruiting
Long-term follow-up for alcoholic liver cirrhosis treatment
This study checks on patients with alcoholic liver cirrhosis who previously received an experimental treatment called Cellgram-LC. It aims to track their health over time to learn more about the treatment's long-term effects.
AnsanAges 19–70 - NCT05090267Recruiting
Gut-brain treatments for alcohol use and memory changes
This study tests whether gut-brain–targeted treatments (including probiotics and stimulation of a nerve) can improve thinking and inflammation-related health in people who use alcohol. You may be able to join if you have memory/thinking problems and meet specific medical limits, including HIV immune system levels.
Coral Gables, FloridaAges 35–70 - NCT05042102RecruitingPhase 2
Donepezil plus brain training for alcohol use disorder
This Phase 2 study tests whether donepezil, along with structured cognitive (brain) training, can improve outcomes for people with alcohol use disorder. It will measure whether this combination helps after recent heavy drinking, while tracking safety over about 13 weeks.
West Haven, ConnecticutAges 18–80 - NCT05028062RecruitingPhase 4
Naltrexone injections for people who want to cut alcohol drinking
This Phase 4 study tests whether naltrexone injections can help people with alcohol use disorder (AUD) reduce or stop heavy drinking. You may get two injections over 8 weeks, and you can join if you meet specific drinking pattern and eligibility rules.
Philadelphia, PennsylvaniaAges 18–65 - NCT05018481RecruitingEarly Phase 1
Study for moderate alcoholic hepatitis after heavy drinking
This early-phase study is testing a treatment approach for people with alcoholic hepatitis (liver inflammation caused by heavy alcohol use). It may help by improving liver function and outcomes in people who meet specific lab and health criteria.
Cleveland, OhioAges 21–65 - NCT04929288Recruiting
Study how hormones affect alcohol risk in men and women
This study looks at how brain activity and hormone-related factors may help explain differences in alcohol risk between men and women. It may help researchers understand why alcohol use differs by sex and how risk develops.
Columbus, OhioAges 21–26 - NCT04858412Recruiting
Amino acid supplement to help people with COVID-19 and alcohol liver disease
This study tests whether an HMB-enriched amino acid supplement can improve outcomes in adults who have COVID-19 pneumonia, especially those with alcohol-related liver disease. The trial compares results in people with alcohol liver disease versus those without, to see if the supplement helps during recovery.
Cleveland, OhioAges 21 years+ - NCT04786587Recruiting
Study of alcohol reporting during pregnancy
This study looks at how alcohol use is reported during pregnancy. It may help improve how pregnant people share this information during prenatal care.
LilleAges 18 years+ - NCT04690972Recruiting
Collection of blood and tissue samples for liver disease research
This study builds a research library of biological samples (like tissue and blood) from people with chronic liver disease. It aims to create better lab and preclinical models of tumors and long-term liver problems, which may help future treatments.
StrasbourgAges 18 years+ - NCT04714892Recruiting
Taste and smell differences in obesity
This study looks at how taste and smell may differ in people with obesity compared to healthy-weight individuals. It aims to understand why some people perceive flavors differently, which could help develop better treatments for weight management.
Bethesda, MarylandAges 18–65 - NCT04689152RecruitingPhase 3
Cell treatment via liver artery catheter for alcoholic cirrhosis
This Phase 3 trial tests whether a cell medicine called Cellgram-LC, delivered through a catheter into the liver artery, is safer and works better for people with alcoholic cirrhosis. It may help improve outcomes in people with more advanced liver scarring.
AnsanAges 20–71 - NCT04400604Recruiting
Study of liver disease risk from heavy alcohol use
This study looks at people with heavy alcohol use who may have alcohol-related liver damage. It aims to better understand liver disease risk and how it changes over time, using blood tests, some scans, and possibly stored tissue.
LilleAges 18–75 - NCT04365855Recruiting
Study of fatty liver risk in local adults
This study looks at how common fatty liver disease is and what factors may be linked to it in adults in Olmsted County. You may be asked about health history, alcohol use, and possibly to undergo MRI scans.
Rochester, MinnesotaAges 18 years+ - NCT04351958Enrolling by invitation
AR videogame to prevent alcohol use in teens
This trial tests whether an augmented-reality (AR) videogame can help teens avoid drinking and reduce harm from alcohol. If you’re 16–18 and in high school, you may be asked to play the AR game during short sessions to see how well it works.
New Haven, ConnecticutAges 16–18 - NCT04250259RecruitingPhase 2
SAMe treatment study for alcoholic cirrhosis
This Phase 2 study tests whether SAMe can help people with alcoholic cirrhosis (scarred liver) who are in early to mid stages. It may also include healthy volunteers to compare safety and blood/body measurements.
Los Angeles, CaliforniaAges 18–70 - NCT04066192RecruitingPhase 2
Brexpiprazole trial for alcohol use disorder in adults
This study tests whether brexpiprazole can help adults with alcohol use disorder. You must currently not be taking alcohol-focused treatment or alcohol medicines, and you’ll likely complete questionnaires and brain scans.
Aurora, ColoradoAges 21–65 - NCT04141592Recruiting
Study immune and disease changes in fatty liver
This study looks at what drives non-alcoholic fatty liver disease and how it affects the body, including immune-related changes. You may be invited if you have confirmed fatty liver disease or, alternatively, if you are a healthy person with no liver disease.
London, Greater LondonAges 18 years+
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Common questions
- Are there clinical trials for alcohol?
- Yes. Clin2 currently lists 527 recruiting alcohol studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alcohol trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alcohol trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.