Clinical trials
Alcohol Dependence clinical trials
Below are recruiting alcohol dependence clinical trials, each written for real people, not researchers. We’re tracking 19 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07388693Recruiting
Virtual reality with scents for alcohol craving
This study tests if adding scents to virtual reality scenes helps people with alcohol dependence manage cravings. You may be eligible if you often feel strong urges to drink and have been sober for at least a week.
Berlin, State of BerlinAges 18–65 - NCT07216872Recruiting
Deep TMS to reduce heavy drinking in alcohol use disorder
This trial tests a non-invasive brain stimulation device (Deep TMS) to help people with alcohol use disorder reduce or stop heavy drinking. It uses magnetic pulses to target brain areas linked to addiction.
Tuscaloosa, AlabamaAges 18–86 - NCT06939088RecruitingPhase 2
Tirzepatide for alcohol reduction in schizophrenia
This trial tests if tirzepatide, a once-weekly injection, can help reduce heavy drinking in people who have both schizophrenia and alcohol use disorder. If you struggle with alcohol and have stable schizophrenia, this study may offer a new treatment option.
Aalborg, DenmarkAges 18–70 - NCT06845124RecruitingPhase 2
Testing CBD and naltrexone for alcohol craving
This trial is testing if taking cannabidiol (CBD) plus naltrexone can reduce alcohol craving in people with alcohol dependence. Naltrexone is already used to help with alcohol cravings, and CBD may add extra benefit.
Wiesloch, Baden-WurttembergAges 18–70 - NCT06675539Recruiting
Testing a tool to predict alcohol withdrawal severity in French speakers
This study tests a French version of a questionnaire (PAWSS) that helps doctors predict how severe alcohol withdrawal might be. It is for people aged 18 to 60 who are dependent on alcohol and planning a supervised detox or being hospitalized for another reason.
ÉtampesAges 18–60 - NCT06405607RecruitingPhase 2
Psilocybin vs Ketamine for Alcohol Use Disorder Trial
This trial tests two psychedelic-assisted therapies, psilocybin and ketamine, to see which works better for reducing heavy drinking in people with alcohol use disorder (AUD). You'll receive either drug along with counseling, and the study monitors safety closely.
Iowa City, IowaAges 21–65 - NCT06265506Recruiting
Virtual Reward Program for Cutting Back on Heavy Drinking
This study tests a virtual program that rewards you for reducing heavy drinking. You'd use a phone app, check in via Zoom, and get a glimpse into your drinking patterns through a blood test. It might be a good fit if you want to cut back on heavy drinking without going to an in-person clinic.
Spokane, WashingtonAges 18 years+ - NCT06262958Recruiting
Early help for teen alcohol and substance issues
This study looks at early help for alcohol and substance use in teenagers. The goal is to see if early support can improve outcomes for young people who have been treated at a psychiatric clinic.
KuopioAges 14–19 - NCT04164940Recruiting
Tracking how hospital care affects alcohol risk in older adults
This study looks at how adults aged 21+ change over time after being admitted to the hospital for alcohol-related problems. It may help researchers understand which hospital approaches work best for reducing future alcohol-related harm—especially for people who have not had alcohol or drug use disorders before.
StavangerAges 21 years+ - NCT06173973Enrolling by invitationPhase 2/Phase 3
Ketone supplement for alcohol withdrawal symptoms
This study tests whether a special supplement (ketones) can help people feel better during alcohol withdrawal. It is for adults who are already in a treatment program for alcohol withdrawal.
Philadelphia, PennsylvaniaAges 18–75 - NCT06850428Recruiting
Alcohol recovery, sleep patterns, and activity levels
This study looks at how physical activity and your natural sleep-wake patterns (chronotype) relate to recovery from alcohol dependence. If you’re in remission and not currently drinking, researchers want to see how these factors affect your well-being.
Ankara, KeçiörenAges 18–65 - NCT05620940RecruitingPhase 1
IV drug safety and absorption study in healthy men
This Phase 1 study tests two experimental medicines given by IV to healthy men. It checks safety and how the body absorbs and processes the drugs (their “pharmacokinetic” profile).
Herston, QueenslandAges 18–55 - NCT05738174Recruiting
High-dose brain stimulation to help treat alcohol addiction
This trial studies a type of noninvasive brain stimulation to reduce alcohol dependence and help people drink less or stop. You may be offered an accelerated treatment schedule, with regular check-ins and questionnaires to track progress.
RegensburgAges 18–65 - NCT06684483Recruiting
Heavy alcohol use and your mouth health
This study looks at how heavy alcohol use affects your saliva and mouth health. It compares people with alcohol use disorder to healthy volunteers to see if the heavy drinking changes the mouth's natural defenses.
Bethesda, MarylandAges 18–100 - NCT07824089Recruiting
Exercise training to reduce alcohol use and liver damage
This study tests whether a supervised exercise program can help people with alcohol-related liver disease drink less and reduce liver injury. It may work by boosting a natural hormone called FGF21, which helps regulate alcohol intake.
Cleveland, OhioAges 18 years+ - NCT04014413Recruiting
Fecal transplant for gut and immune-related conditions
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
Hong Kong, ShatinAges Any age - NCT06308484Recruiting
Mindfulness and brain stimulation for alcohol recovery
This trial tests if combining a non-invasive brain stimulation technique (like a mild electrical current) with mindfulness training can help people with alcohol dependence stay sober. If you recently stopped drinking and meet the health requirements, you may be able to join.
Berlin, State of BerlinAges 18–70 - NCT01730781Recruiting
PET scan study to image cannabinoid receptors in the brain
This study uses a special brain scan (PET) to measure cannabinoid receptors—areas in the brain that interact with cannabis-like chemicals. It may help researchers better understand how these receptors relate to conditions such as schizophrenia, PTSD, opioid use disorder, or early psychosis risk.
New Haven, ConnecticutAges 18–55 - NCT06701487Recruiting
Brain learning mechanisms and substance use control
This study looks at how certain learning mechanisms in the brain (called Pavlovian conditioning) influence your ability to control alcohol or drug use. It may help explain why some people have trouble stopping, and could lead to better treatments. You'll fill out questionnaires and likely have a brain scan (MRI).
DresdenAges 18–65
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Alcohol Dependence trials by city
Studies with a site in or near these metro areas.
Alcohol Dependence trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for alcohol dependence?
- Yes. Clin2 currently lists 19 recruiting alcohol dependence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alcohol dependence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alcohol dependence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.