Clinical trials · Maryland
Amyotrophic Lateral Sclerosis clinical trials in Maryland
We’re tracking 15 recruiting amyotrophic lateral sclerosis studies with a site in Maryland — including Early Phase 1, Phase 1 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Maryland
- NCT07491484Recruiting
Physical function and quality of life in ALS patients
This trial measures how physical function affects daily life and well-being in people with ALS. It aims to understand how movement abilities impact patient-reported outcomes.
Salisbury, MarylandAges 18 years+ - NCT07290062RecruitingPhase 1
Gene therapy injection for ALS safety study
This trial tests a single injection of a gene therapy called INS1202 into the spinal fluid. It is for people with ALS, including those with a specific genetic form (SOD1 mutation). The goal is to see if it is safe and how it affects the body.
Baltimore, MarylandAges 18–79 - NCT07221240RecruitingPhase 1
Amisodin safety study for healthy adults with ALS
This trial tests a new drug called Amisodin in healthy adults who also have ALS. It checks if the drug is safe and how the body processes it.
Baltimore, MarylandAges 18–55 - NCT07204977RecruitingPhase 1
Acamprosate for ALS with C9orf72 gene change
This trial tests a medication called acamprosate to see if it can slow down ALS in people who have a specific genetic change (C9orf72). If you have this gene change and ALS, this study might offer a new treatment option.
Bethesda, MarylandAges 18–99 - NCT06656702RecruitingEarly Phase 1
Psilocybin for depression in amyotrophic lateral sclerosis
This trial tests whether psilocybin, a psychedelic drug, can safely help with depression in people with ALS. It also looks at how the drug affects your symptoms and quality of life over six months.
Baltimore, MarylandAges 18 years+ - NCT04394871Recruiting
Study of ALS and related genetic nerve disorders using scans and fluid tests
This study looks at signs and biology (biomarkers) in people with certain inherited nerve conditions caused by RNA-processing gene changes. It may help researchers understand disease patterns and measure health changes using MRI scans and sometimes a spinal fluid test.
Bethesda, MarylandAges 5–120 - NCT04363684Recruiting
Study of frontotemporal dementia and related syndromes over time
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Baltimore, MarylandAges 18 years+ - NCT03225144Recruiting
Study of gene and disease changes in ALS and frontotemporal dementia
This study looks at complex brain and body changes in people with ALS and frontotemporal dementia (FTD), or related disorders. If you have one of these diagnoses—or a known gene mutation that can cause ALS/FTD—you may be able to help researchers learn how the conditions progress.
Bethesda, MarylandAges 18–110 - NCT07823101Recruiting
Imaging study of swallowing and speech muscles in muscle diseases
This study uses imaging to look at the muscles involved in swallowing and speaking in people with certain muscle diseases, like inclusion body myositis or ALS. The goal is to better understand these conditions, which might help improve care in the future.
Baltimore, MarylandAges 18 years+ - NCT07521930Recruiting
Brain implant to restore communication and movement control
This trial tests a surgically implanted brain device designed to help people with severe paralysis or movement disorders regain the ability to communicate and control their limbs. The device reads signals from your brain and translates them into commands that could help you interact with computers or assistive technology.
Baltimore, MarylandAges 18–80 - NCT07322003RecruitingPhase 3
Pridopidine for ALS: Phase 3 trial testing safety and effectiveness
This trial is testing if an oral medication called pridopidine can slow the progression of ALS. It is for people recently diagnosed with ALS who have mild to moderate breathing function and meet specific risk scores.
Baltimore, MarylandAges 18–80 - NCT06581861Recruiting
Family study to prevent ALS and FTD
This study is for adults who have a strong family history of ALS or FTD (like a parent or sibling with the disease) to help researchers understand how to prevent these conditions. It involves following you for about a year to track your health.
Baltimore, MarylandAges 18 years+ - NCT06578195Recruiting
Assess all ALS study
This study follows people with ALS and healthy volunteers over time to understand the disease better. You can join from home using a smartphone or computer.
Baltimore, MarylandAges 18 years+ - NCT03127267RecruitingPhase 3
Test of masitinib versus placebo for ALS
This Phase 3 study tests whether masitinib works better than an inactive pill (placebo) to slow ALS progression and keep it safe. It is meant for people recently diagnosed with ALS who meet specific breathing and function score requirements.
Baltimore, MarylandAges 18–81 - NCT03567213Recruiting
CortiCom brain signal system for communication in severe paralysis
This trial tests a system that records brain signals to help people with severe paralysis and little or no speech communicate. It involves a surgical implant and frequent study visits to see if the system can work safely and reliably for communication.
Baltimore, MarylandAges 22–70
Amyotrophic Lateral Sclerosis trials by city in Maryland
Where these studies are running in Maryland
Institutions with a site for the recruiting amyotrophic lateral sclerosis studies listed above.
- Johns Hopkins University · 5 studies
- National Institutes of Health Clinical Center · 3 studies
- Johns Hopkins Medicine · 2 studies
- Nih/Ninds · 2 studies
- Johns Hopkins Hospital
- Johns Hopkins Medicine Brain Science Institute
- National Institutes of Health
- Pharmaron, Inc.
What taking part in a amyotrophic lateral sclerosis study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Amyotrophic Lateral Sclerosis trials in other states
Common questions
- Are there amyotrophic lateral sclerosis clinical trials in Maryland?
- Yes. We're currently tracking 15 recruiting amyotrophic lateral sclerosis studies with a site in Maryland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a amyotrophic lateral sclerosis study in Maryland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Maryland to take part?
- Not necessarily. These studies have a site in Maryland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a amyotrophic lateral sclerosis trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New amyotrophic lateral sclerosis studies open in Maryland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.