Clinical trials · Florida
Amyotrophic Lateral Sclerosis clinical trials in Florida
We’re tracking 26 recruiting amyotrophic lateral sclerosis studies with a site in Florida — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Florida
- NCT04363684Recruiting
Study of frontotemporal dementia and related syndromes over time
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Jacksonville, FloridaAges 18 years+ - NCT07023835RecruitingPhase 2
Testing usnoflast for ALS
This trial tests an experimental oral medication called usnoflast for people with ALS. It aims to see if the drug can slow the disease's progression.
Tampa, FloridaAges 18 years+ - NCT03489278Recruiting
Support procedures study for ALS using electronic health records
This study is about improving the research process for people with ALS by using electronic health records from participating clinics. If you have ALS and receive care at an Epic-using center, you may be asked to help with consent and study procedures.
Miami, FloridaAges 18 years+ - NCT05474235Recruiting
ALS and motor neuron disease studies for patients, family, and controls
This study looks at people with amyotrophic lateral sclerosis (ALS), people who might have ALS, and also people related to someone with ALS. It may help researchers better understand ALS and related “motor neuron” conditions, and it involves participation that may include blood tests.
Jacksonville, FloridaAges 18 years+ - NCT07187388Recruiting
Electrical stimulation for jaw pain in motor neuron disease
This study tests whether gentle electrical stimulation around the jaw can ease facial pain, improve jaw movement, and help oral health in people with certain motor neuron diseases like ALS or PLS. It may be a good fit if you have jaw pain and meet a few health conditions.
Davie, FloridaAges 18 years+ - NCT07295990Recruiting
Tongue exercises for people with ALS
This trial tests whether simple tongue-strengthening exercises can help people with ALS who have mild swallowing trouble. If you have ALS and notice your tongue getting weaker, this study may help you keep your swallowing strength.
Davie, FloridaAges 18–99 - NCT00317616Recruiting
Study for people at high risk of ALS before symptoms start
This study follows healthy people from families with a known ALS-causing gene mutation to look for early body or brain changes before symptoms begin. It may help researchers find ways to predict ALS risk earlier so future treatments can start sooner.
Miami, FloridaAges 18 years+ - NCT07543367Recruiting
Brain implant to restore arm movement in ALS
This study tests a surgically implanted brain-computer interface (BCI)—a device that reads signals directly from your brain to help control a computer cursor or robotic arm. It's designed for people with ALS whose arms are paralyzed and who haven't responded to standard treatments.
Jacksonville, FloridaAges 22 years+ - NCT05395624RecruitingPhase 1/Phase 2
Safety imaging study of a PET tracer in ALS, Alzheimer, MS, Parkinson
This early-phase study tests the safety of a radioactive tracer (“18F-OP-801”) and how the tracer moves through the body (biodistribution) in people with ALS, Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, and in healthy volunteers. It also measures how the body processes the tracer (“pharmacokinetics”) to support future studies.
Jacksonville, FloridaAges 18–80 - NCT05104710Recruiting
Testing brain–muscle coordination as a marker in ALS
This study measures how well your nerves and muscles work together to see if it can serve as an early sign (a “biomarker”) of ALS. It may help doctors track ALS more accurately, especially in people who already seem to have ALS based on nerve testing.
Miami, FloridaAges 20–90 - NCT07161999RecruitingPhase 2/Phase 3
COYA 302 treatment for ALS
This study tests an experimental treatment called COYA 302 for ALS. It aims to see if it can slow down the worsening of muscle weakness and improve daily function. It might be an option for people in the earlier stages of ALS.
Davie, FloridaAges 18–80 - NCT06609213Recruiting
Testing a nutrition drink before feeding tube placement in ALS
This trial tests if drinking a special nutrition formula for a few weeks before getting a feeding tube can help people with ALS tolerate tube feeding better. It aims to reduce side effects like bloating or discomfort.
Fort Lauderdale, FloridaAges 18 years+ - NCT06735014Recruiting
ALS imaging study to track disease progression
This study uses MRI brain scans to understand how ALS affects the brain over time. It may help researchers develop better ways to measure the disease.
Gainesville, FloridaAges 18 years+ - NCT06578195Recruiting
Assess all ALS study
This study follows people with ALS and healthy volunteers over time to understand the disease better. You can join from home using a smartphone or computer.
Davie, FloridaAges 18 years+ - NCT07322003RecruitingPhase 3
Pridopidine for ALS: Phase 3 trial testing safety and effectiveness
This trial is testing if an oral medication called pridopidine can slow the progression of ALS. It is for people recently diagnosed with ALS who have mild to moderate breathing function and meet specific risk scores.
Jacksonville, FloridaAges 18–80 - NCT07142291RecruitingPhase 2
Cromolyn inhaler for early ALS
This trial tests if an inhaled drug called cromolyn can help people with early-stage ALS. It is for people who can still breathe well and are not yet using a ventilator.
Jacksonville, FloridaAges 18–75 - NCT05116943Recruiting
ALS and related brain disease biospecimen biobank
This study builds a blood and spinal fluid (lumbar puncture) sample library from people with ALS, ALS-FTD, or similar neurodegenerative diseases. Your samples help researchers study these conditions, even if you are not receiving a new treatment.
Jacksonville, FloridaAges 18 years+ - NCT05137665Recruiting
Study tracks ALS and health markers over time at home
This study follows people with ALS and healthy volunteers to measure how specific body fluids, symptoms, and at-home tracking change over time. It may help researchers find early signs of disease changes and better ways to measure treatment effects.
Jacksonville, FloridaAges 18 years+ - NCT06429735Recruiting
Robot-implanted brain-computer interface for severe paralysis
This trial tests a brain-computer interface (a device that lets you control a computer with your thoughts) that is implanted by a robot. It is for people with severe paralysis who may benefit from a new way to communicate or control devices.
Miami, FloridaAges 22–75 - NCT06527222RecruitingPhase 2
Ranolazine for muscle cramps in ALS
This trial tests if a heart medication called ranolazine can reduce painful muscle cramps in people with ALS. If you experience frequent cramps and meet the other criteria, this study may be an option for you.
Jacksonville, FloridaAges 18 years+ - NCT06581861Recruiting
Family study to prevent ALS and FTD
This study is for adults who have a strong family history of ALS or FTD (like a parent or sibling with the disease) to help researchers understand how to prevent these conditions. It involves following you for about a year to track your health.
Jacksonville, FloridaAges 18 years+ - NCT06665165RecruitingPhase 1
Study of AMX0114 for people with ALS
This study tests an experimental drug called AMX0114 for people recently diagnosed with ALS. It is an early-phase trial to see if the drug is safe and how it affects the body.
Orlando, FloridaAges 18 years+ - NCT07287397RecruitingPhase 1/Phase 2
Testing VTx-002 for safety in ALS patients
This trial tests a new drug called VTx-002 to see if it is safe and tolerable for people with ALS. You may be able to join if you have had symptoms for less than 18 months and have a caregiver who can help.
Jacksonville, FloridaAges 18 years+ - NCT00136500Recruiting
Research study for people with ALS and family risk
This study looks at people affected by ALS (a nerve disease) and, in some cases, family members who may be at genetic risk. It may help researchers better understand ALS and related conditions and improve how they’re studied.
Miami, FloridaAges 18 years+
Amyotrophic Lateral Sclerosis trials by city in Florida
Where these studies are running in Florida
Institutions with a site for the recruiting amyotrophic lateral sclerosis studies listed above.
- Mayo Clinic · 13 studies
- University of Miami · 7 studies
- Nova Southeastern University · 5 studies
- University of Florida · 3 studies
- University of South Florida · 2 studies
- Orlando Health
- Zydus US012
What taking part in a amyotrophic lateral sclerosis study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Amyotrophic Lateral Sclerosis trials in other states
Common questions
- Are there amyotrophic lateral sclerosis clinical trials in Florida?
- Yes. We're currently tracking 26 recruiting amyotrophic lateral sclerosis studies with a site in Florida, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a amyotrophic lateral sclerosis study in Florida?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Florida to take part?
- Not necessarily. These studies have a site in Florida, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a amyotrophic lateral sclerosis trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New amyotrophic lateral sclerosis studies open in Florida regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.