Clinical trials
Anterior Cruciate Ligament Reconstruction clinical trials
Below are recruiting anterior cruciate ligament reconstruction clinical trials, each written for real people, not researchers. We’re tracking 125 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07041242Recruiting
ACL reconstruction outcomes in older vs. younger adults
This study compares how well a specific type of ACL knee surgery works in people over 50 versus those under 30. It looks at results and problems after surgery to see if the technique is safe and effective for older patients.
Bologna, BolognaAges 18 years+ - NCT07043569Recruiting
Strength training with blood flow restriction after ACL surgery
This trial tests a special type of strength training that uses a blood pressure cuff to limit blood flow during exercises. It aims to help people recover muscle strength and improve knee function after ACL surgery.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07023653Recruiting
ACL repair: comparing all-inside vs. standard tunnel surgery
This study compares two ways of repairing a torn ACL: a newer 'all-inside' method versus a standard tunnel method. It is designed for adults with a simple ACL tear, not for those with multiple ligament injuries, severe cartilage damage, or active infection.
DepokAges 18–65 - NCT07020312RecruitingPhase 2
Brain training to improve muscle recovery after joint surgery
This trial tests whether brain-computer interface training can help you regain muscle control more effectively after knee or hip surgery. It focuses on four common procedures and uses neurofeedback to optimize muscle activation during recovery.
Chicago, IllinoisAges 18 years+ - NCT06991192Recruiting
ACL surgery rehab with exercise and mental support
This study tests a rehab program that combines physical exercises with psychological support to help young athletes recover from ACL surgery and return to sports safely.
Bloomington, MinnesotaAges 15–25 - NCT06979804Recruiting
Comparing knee surgery outcomes with special fabric products
This study compares how well people do after anterior cruciate ligament (ACL) surgery, with or without also repairing the meniscus, using a special fabric product. It aims to see if the fabric helps improve recovery and outcomes for people with these common knee injuries.
Westmont, IllinoisAges 16–65 - NCT06972914Enrolling by invitation
Brace wearing time after ACL surgery recovery study
This trial tests how long patients should wear a brace after anterior cruciate ligament (ACL) reconstruction surgery. It aims to find the best duration for faster short-term recovery.
Chongli, HebeiAges 18 years+ - NCT06973642Recruiting
Home-based rehab after ACL surgery via phone
This trial tests whether a home-based rehab program using your phone can help people recover after anterior cruciate ligament (ACL) reconstruction. It aims to see if remote physical therapy is as effective as in-person sessions.
Jackson, MississippiAges 18 years+ - NCT06974526RecruitingPhase 2
Study of a dissolvable implant for recovery after ACL surgery
This study tests whether a dissolvable implant that releases a medication called oxandrolone can improve recovery after ACL surgery. Oxandrolone may help strengthen the new ligament and speed up healing.
Fortaleza, CearáAges 18–60 - NCT06955026Recruiting
Hockey slideboard and blood flow restriction for ACL rehab
This trial tests if using a hockey slideboard with blood flow restriction (a special band that limits blood flow during exercise) helps recovery after ACL surgery. It may improve muscle strength and function faster.
Odorheiu Secuiesc, RomaniaAges 18–45 - NCT06942754Recruiting
Bracing vs. surgery for ACL tears
This study compares two ways to treat a torn ACL: bracing alone or surgery using your own quadriceps tendon. It aims to find which option helps you return to sports best.
Winston-Salem, North CarolinaAges 14–39 - NCT06905691Recruiting
Eccentric training after ACL reconstruction
This study tests if a specific exercise (eccentric training) helps people recover better after ACL surgery. You may join if you are between 18 and 40 and are scheduled for this surgery.
Veranópolis, Rio Grande do SulAges 18–40 - NCT06910150Enrolling by invitation
Pain relief after knee surgery: electric stimulation study
This trial tests two types of mild electric stimulation (one with tiny needles, one without) applied to the thigh muscle to reduce pain in people who had ACL knee surgery in the last six weeks. The goal is to see if this can help you feel better and recover quicker.
Madrid, MadridAges 18–55 - NCT06875427RecruitingPhase 3
Nerve block vs no block for ACL surgery in kids
This trial tests whether a nerve block (a numbing shot) before ACL reconstruction helps young patients have less pain and better recovery compared to no block.
Hamilton, OntarioAges 10–18 - NCT06858930Recruiting
Navigation system for ACL reconstruction
This trial tests a special computer navigation system to help surgeons place the new ACL graft more precisely during knee reconstruction. If you have a torn ACL and are between 18 and 80, this study might help improve your surgery outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT06858293Recruiting
Imagining exercises to boost knee strength after ACL surgery
This study tests whether imagining yourself doing exercises can help you regain strength in your thigh muscle after ACL surgery, and if it's something people can stick with during physical therapy.
Milwaukee, WisconsinAges 18 years+ - NCT06868147Recruiting
Long-term results of a second ACL reconstruction using a tendon graft
This study looks at people who had a second surgery to fix a torn ACL in their knee. The surgery used a special technique with a tendon from the Achilles. Researchers want to see how well the knee works and looks on X-rays at least 2 years after that surgery.
BolognaAges 18–50 - NCT06819696Recruiting
Comparing two ACL reconstruction surgery methods
This trial compares two ways of doing anterior cruciate ligament (ACL) reconstruction surgery: using a tourniquet to control bleeding, or using a special sheath that allows fluid to flow in and out. The goal is to see which method works better during surgery.
Reims, MarneAges 18 years+ - NCT06818201Recruiting
Brain stimulation for ACL surgery recovery
This study tests if a gentle, noninvasive brain stimulation called tDCS can improve how your brain controls leg muscles and speeds up recovery after ACL surgery.
Valencia, ValenciaAges 16–40 - NCT06762392Recruiting
Blood flow restriction for ACL rehab: a pilot study
This study tests whether using a special band that slightly restricts blood flow (blood flow restriction) during rehabilitation can help people recover better after ACL knee surgery. It's a small early study to see if this method is safe and effective.
Valencia, ValenciaAges 18 years+ - NCT06688344Recruiting
Shock wave therapy after ACL surgery
This trial tests if adding focused shock wave therapy to standard rehab can improve recovery after ACL reconstruction using a hamstring graft. It may help reduce pain and speed up healing.
IstanbulAges 18–45 - NCT06662955Recruiting
Exercise with sound cues after ACL reconstruction
This study tests if adding sounds (like a metronome beat) to your rehab exercises helps your leg muscles work better after ACL reconstruction. It is for athletes who had their ACL surgery within the past 2 weeks and are ready to start moving.
Salaya, Changwat Nakhon PathomAges 18–35 - NCT07636278Recruiting
Augmented Reality guidance for ACL knee surgery
This trial tests whether using augmented reality (special computer graphics overlaid on surgical video) during ACL reconstruction surgery helps surgeons perform the procedure more accurately. You would undergo standard knee surgery, but the surgeon would have real-time computer guidance to assist with precision.
Milan, MichiganAges 18 years+ - NCT06636045Enrolling by invitation
Blood flow restriction after ACL surgery with quad graft
This study tests whether using a special blood flow restriction cuff after ACL surgery helps you recover faster and stronger. It is for people having ACL reconstruction using their own quadriceps tendon for the first time.
Kansas City, KansasAges 14–40
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Common questions
- Are there clinical trials for anterior cruciate ligament reconstruction?
- Yes. Clin2 currently lists 125 recruiting anterior cruciate ligament reconstruction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anterior cruciate ligament reconstruction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anterior cruciate ligament reconstruction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Anterior Cruciate Ligament Reconstruction Rehabilitation
- Anterior Cruciate Ligament (ACL) Reconstruction
- Anterior Cruciate Ligament Injuries
- Anterior Cruciate Ligament Rupture
- ACL - Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Tear
- Anterior Cruciate Ligament (ACL) Tear
- Anterior Cruciate Ligament
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.