Clinical trials
Arthritis clinical trials
Below are recruiting arthritis clinical trials, each written for real people, not researchers. We’re tracking 550 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07564154RecruitingPhase 1
Testing KT502 injections for active rheumatoid arthritis
This is an early-stage study testing a new injectable treatment called KT502 for people with moderate-to-severe rheumatoid arthritis (RA) that hasn't responded well to standard treatments. The study will check if the medication is safe and how the body responds to it.
Bayswater, VictoriaAges 18–75 - NCT07207954RecruitingPhase 1
Testing LFD-200 in healthy adults and adults with rheumatoid arthritis
This study tests a new drug, LFD-200, in healthy adults and in adults with moderate to severe rheumatoid arthritis who have active symptoms despite methotrexate. The goal is to see if it's safe and how it affects the disease.
MelbourneAges 18–75 - NCT07137598RecruitingPhase 2
A study of RO7790121 for moderate to severe rheumatoid arthritis
This study tests a new drug, RO7790121, for people with rheumatoid arthritis (RA) who have not gotten better with or could not tolerate common treatments like TNF inhibitors or JAK inhibitors. It aims to see if the drug is safe and can help reduce joint pain and swelling.
Peoria, ArizonaAges 18 years+ - NCT07620392RecruitingPhase 2
Long-Term Safety Study of Afimkibart for Rheumatoid Arthritis
This is a follow-up study for people who already completed a previous trial testing afimkibart (an experimental drug) for rheumatoid arthritis. It checks whether the drug continues to work safely and effectively over a longer period.
Tamarac, FloridaAges 18 years+ - NCT07406035RecruitingPhase 2
Testing TQH3906 for active psoriatic arthritis
This trial tests a new capsule, TQH3906, for people with active psoriatic arthritis who haven't had success with other treatments. It aims to see if the drug is safe and works well for joint and skin symptoms.
Bozhou, AnhuiAges 18–70 - NCT07721142RecruitingPhase 4
Chinese medicine and Western medicine for hard-to-treat rheumatoid arthritis
This trial combines traditional Chinese herbal medicine with standard Western treatments for people with rheumatoid arthritis that hasn't responded well to at least two prior medications. It aims to see if the combination is more effective and safe.
ShanghaiAges 18–70 - NCT07718815Recruiting
HLA B leader study in psoriatic arthritis
This study looks at a specific genetic marker (HLA B leader) in people with psoriatic arthritis compared to healthy individuals. It may help researchers understand how this gene affects the disease.
Amiens, PicardieAges 18 years+ - NCT07180537Recruiting
Health course for joint and mood conditions
This study tests an online health course that helps improve diet and self-care to support cell health and wellbeing. It is for people with certain rheumatological conditions like rheumatoid arthritis, lupus, or psoriatic arthritis, who also have mood concerns.
Iowa City, IowaAges 18–100 - NCT05609630RecruitingPhase 3
Testing two medicines for active systemic juvenile arthritis
This Phase 3 trial studies how well upadacitinib (a pill) and tocilizumab (a shot/IV medicine) improve symptoms and inflammation in children with active systemic juvenile idiopathic arthritis (sJIA). It also looks at side effects and how these medicines move through the body.
Phoenix, ArizonaAges 1–17 - NCT07276958RecruitingPhase 1
Study of LY4298445 for Lupus and Rheumatoid Arthritis
This trial tests a new drug called LY4298445 in healthy people and those with lupus or rheumatoid arthritis. It aims to see if the drug is safe and how the body processes it.
BrisbaneAges 18–55 - NCT06917742RecruitingPhase 1
Study of CPTX2309 for rheumatoid arthritis and lupus
This trial tests an investigational drug called CPTX2309, given intravenously, for people with moderate to severe rheumatoid arthritis or systemic lupus erythematosus. It aims to see if the drug is safe and effective.
Herston, QueenslandAges 18–65 - NCT02991469RecruitingPhase 2
Testing sarilumab for children with systemic juvenile arthritis
This trial studies sarilumab, a targeted medicine, to help reduce symptoms in children and teens with systemic juvenile idiopathic arthritis (sJIA) who have not responded enough to current treatments. You may be considered because the study looks at how well and safely repeated doses work in pediatric patients.
San Miguel de Tucumán, Tucumán ProvinceAges 1–17 - NCT03048201Recruiting
Total Knee Replacement Registry Study for a Specific Knee Implant
This study tracks outcomes for people getting a total knee replacement using a specific knee implant system. It may help doctors understand which patients do best and how the implant performs over time.
Rancho Mirage, CaliforniaAges 22 years+ - NCT03248284Recruiting
Study of inflammation in Achilles tendons in psoriatic arthritis
This trial studies people with psoriatic arthritis who have painful Achilles tendon insertion with signs of inflammation on ultrasound. It may help researchers better understand what drives tendon inflammation and how it can be treated.
OdenseAges 18–70 - NCT03245801Recruiting
Juvenile arthritis registry for newly diagnosed children
This study collects information about children with juvenile idiopathic arthritis (JIA) soon after diagnosis. The information helps researchers understand how the condition and treatments change over time, and it may guide future care.
Calgary, AlbertaAges Up to 18 years - NCT03297775Recruiting
Studying rheumatoid arthritis treatment risks for lung scarring
This trial is for people with rheumatoid arthritis (RA) who are at risk for developing interstitial lung disease, which is scarring in the lungs. It aims to better understand why this happens and how to help prevent or manage it.
Aurora, ColoradoAges 45–90 - NCT03414502RecruitingPhase 3
Predictors of Response to DMARDs in Rheumatoid Arthritis
This trial studies rheumatoid arthritis (RA) patients starting or adjusting DMARD medicines and looks for signs that predict who responds best. It may help doctors choose more effective treatment sooner.
Omaha, NebraskaAges 19 years+ - NCT03722537Recruiting
Test of cartilage graft surgery for thumb arthritis pain
This trial looks at using a donated cartilage-and-bone graft during surgery for thumb “basal joint” arthritis. It may help reduce pain and improve thumb function if you are planning surgery for this condition.
New York, New YorkAges 18 years+ - NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune conditions
This Phase 1 study tests nivolumab, an immunotherapy “anti-cancer accelerator,” in people with advanced cancer who also have an autoimmune disorder. It aims to see if nivolumab can be given safely and whether it may help shrink or control cancer.
Birmingham, AlabamaAges 18 years+ - NCT03976245RecruitingPhase 4
Tested new advanced treatment options for rheumatoid arthritis
This trial studies advanced medicines for rheumatoid arthritis (RA) in people whose RA is still active despite several standard treatments. It may help by testing whether a different advanced option can better control symptoms and joint inflammation.
London, OntarioAges 18 years+ - NCT07401732Recruiting
Dysphagia in rheumatoid arthritis study
This study looks at swallowing problems (dysphagia) in people with rheumatoid arthritis to understand how common they are and what might cause them. It uses a flexible scope through the nose to examine swallowing function.
Tanta, ElgharbiaAges 18 years+ - NCT07315997Recruiting
Heart health study for people with rheumatoid arthritis
This study looks at whether calcium in the heart arteries and a blood test (troponin) can help predict heart disease risk in people with rheumatoid arthritis. It may help doctors better prevent heart attacks and strokes.
Boston, MassachusettsAges 35–79 - NCT04191395Recruiting
Study of treatments for long-term inflammatory diseases
This study looks at how chronic inflammatory illnesses progress over time and how treatments affect symptoms and disease markers. You may be invited if you’re receiving care for certain bowel, joint, or skin inflammatory conditions at the hospital.
BesançonAges 18 years+ - NCT04238143Recruiting
Knee and other joint arthritis tissue therapy
This trial tests a regenerative therapy made from a patient’s own fat tissue (a “cellular” treatment) to reduce pain and improve function in arthritis-related problems. It may help people with inflammatory or degenerative arthritis changes, if they meet safety and tissue-donation requirements.
Valencia, CaliforniaAges 18–90
Hear when a new Arthritis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for arthritis?
- Yes. Clin2 currently lists 550 recruiting arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.