Clinical trials
Atherosclerotic Cardiovascular Disease clinical trials
Below are recruiting atherosclerotic cardiovascular disease clinical trials, each written for real people, not researchers. We’re tracking 68 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06112327Enrolling by invitation
Long-term follow-up for a gene editing heart therapy
This study follows people who already received an experimental gene editing treatment for cardiovascular disease in a prior Verve trial. The goal is to monitor their health and any long-term effects over time.
AucklandAges 18 years+ - NCT06919302Recruiting
Digital heart health app for heart disease patients
This study tests a digital heart health app combined with lifestyle coaching to help people with heart disease or diabetes manage their cholesterol and overall heart health. It aims to see if the app can improve outcomes for people already taking a statin.
Toronto, OntarioAges 45 years+ - NCT07157774RecruitingPhase 3
Muvalaplin for heart disease in people with high lipoprotein(a)
This study tests a new medicine called muvalaplin that lowers a specific type of cholesterol linked to heart disease. It aims to see if muvalaplin can reduce the risk of future heart attacks, strokes, or related procedures in people with high levels of this cholesterol.
Apache Junction, ArizonaAges 18 years+ - NCT06211868Recruiting
Early heart disease risk study for adults 40-70
This study looks at whether changing your immune system, fats, and metabolism can lower your risk of early heart disease. It is for people with an intermediate to high risk score but who have not yet had a heart attack or stroke.
SingaporeAges 40–70 - NCT06126367Recruiting
Study on lipoprotein(a) and clot breakdown in heart disease
This trial looks at how a type of fat in the blood called lipoprotein(a) and your body's ability to break down clots affect heart disease or heart valve disease. It is for people who are already taking certain cholesterol-lowering medicines or have severe aortic valve narrowing from calcium buildup.
StevenageAges 18 years+ - NCT06932874RecruitingPhase 4
Metformin for diabetes with heart disease
This trial tests a long-acting metformin pill in people with both type 2 diabetes and coronary heart disease. It aims to see if metformin can safely help control blood sugar in this specific group.
Beijing, Beijing MunicipalityAges 30–75 - NCT06784557RecruitingPhase 4
Study of ezetimibe's effect on gut bacteria
This trial tests whether ezetimibe, a cholesterol-lowering drug, changes the bacteria in your gut. It may help people with heart disease or high cholesterol who are already on a statin.
SeoulAges 19–80 - NCT07315997Recruiting
Heart health study for people with rheumatoid arthritis
This study looks at whether calcium in the heart arteries and a blood test (troponin) can help predict heart disease risk in people with rheumatoid arthritis. It may help doctors better prevent heart attacks and strokes.
Boston, MassachusettsAges 35–79 - NCT06793930Recruiting
A personalized program to improve health in metabolic syndrome
This study tests a personalized program that helps people with metabolic syndrome make healthy changes to their diet and activity. It is designed for Chinese adults who live at home and can use a digital device.
Hong KongAges 18 years+ - NCT06813911RecruitingPhase 3
Testing pelacarsen for high Lp(a) in heart disease patients
This trial tests a new medicine called pelacarsen for people with very high Lp(a) (a type of cholesterol) and existing heart or blood vessel disease. It aims to see if adding pelacarsen to your current cholesterol treatment can lower your Lp(a) levels further.
Birmingham, AlabamaAges 18–80 - NCT06875973RecruitingPhase 3
Pelacarsen long-term extension study
This trial is for people who have already finished taking pelacarsen in a previous study. It offers continued access to the drug and checks long-term safety.
Birmingham, AlabamaAges 18–100 - NCT06960902Recruiting
Study of Heart Artery Plaque in Familial Hypercholesterolemia
This study uses a heart CT scan to look for plaque buildup in the arteries of people with familial hypercholesterolemia (a genetic high-cholesterol condition). It aims to understand why some people with FH develop heart disease while others don't.
DijonAges 40 years+ - NCT06962488Recruiting
Personalized blood pressure care using genetic risk
This study uses your genetic information (a polygenic risk score) to guide personalized blood pressure management. It aims to help people with high blood pressure and overall poor heart health improve their levels through tailored advice.
Birmingham, AlabamaAges 18–55 - NCT07034690RecruitingPhase 4
Better cholesterol control for high-risk patients
This study tests whether an educational program can help people with high cholesterol and heart disease get their LDL cholesterol levels lower. It involves watching online videos and working with your doctor to adjust treatments.
Abu DhabiAges 18–100 - NCT07334834Recruiting
Better cholesterol management for people with artery disease
This study tests a team-based approach to help people with artery disease (like heart attacks or leg blockages) get their cholesterol to a healthier level. If your LDL is above 70, you may benefit from extra support to manage your medications.
Aurora, ColoradoAges 18 years+ - NCT06813339RecruitingEarly Phase 1
Testing a new drug in healthy people and those with heart condition
This trial tests a new medicine called UDP-003 in two groups: healthy volunteers and people who had a heart event (acute coronary syndrome) at least a year ago. The goal is to see if the drug is safe and how the body handles it, which could lead to better treatments for heart disease.
Adelaide, South AustraliaAges 18–79 - NCT07581808RecruitingPhase 4
Two cholesterol drugs for heart disease prevention
This study tests two newer cholesterol-lowering medications (inclisiran and alirocumab) together in people who've had heart problems or strokes and cannot tolerate standard cholesterol drugs. The goal is to see if this combination safely lowers cholesterol further and reduces future cardiovascular events.
LjubljanaAges 18 years+ - NCT07237685Recruiting
Diabetes and heart artery plaque progression study
This study uses a follow-up CT scan of your heart arteries to see how diabetes-related plaque buildup changes over time. It may help researchers understand how well current diabetes treatments are protecting your heart.
AmsterdamAges 18 years+ - NCT07151183Recruiting
Panvascular disease: diagnosis, prognosis and causes study
This trial studies people with panvascular disease, which means having cholesterol plaque buildup in at least two different blood vessel areas (like heart, brain, or legs). It aims to understand how to diagnose and predict the outcome of this condition, and what causes it.
Harbin, HeilongjiangAges 18–80 - NCT05677386Enrolling by invitation
CT heart scan trial to prevent first heart problems
This trial uses a special CT scan of the heart’s arteries to better predict who is at risk of future heart problems. It may help your care team decide how best to lower risk early.
CopenhagenAges 40 years+ - NCT05943821RecruitingPhase 3
Allopurinol to lower heart and stroke risks in high-risk people
This trial studies whether allopurinol can reduce the chance of cardiovascular events like heart attack, stroke, or related problems in people who are at higher risk. It targets people with higher uric acid and other risk factors, to see if lowering uric acid helps protect the heart.
Poznan, WielkopolskaAges 40–70 - NCT06595784Recruiting
COPD and heart disease study
This study looks at people who have both COPD (a long-term lung condition) and a heart problem. The goal is to learn more about how these two conditions affect each other and to help doctors provide better care.
AlexandroupoliAges 35–99 - NCT06927739RecruitingPhase 2
Orticumab for heart artery inflammation after a heart attack
This trial tests a drug called orticumab to see if it can reduce inflammation in the arteries of the heart after a heart attack. It may help prevent future heart problems.
Los Angeles, CaliforniaAges 18 years+ - NCT06040073Recruiting
Study of heart artery blockages after heart attack
This study is for people who recently had a heart attack and need an angiogram. It looks at blockages that are not completely blocking blood flow to learn how they change over time.
BeijingAges 18 years+
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Common questions
- Are there clinical trials for atherosclerotic cardiovascular disease?
- Yes. Clin2 currently lists 68 recruiting atherosclerotic cardiovascular disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atherosclerotic cardiovascular disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atherosclerotic cardiovascular disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.