Clinical trials
Azoospermia clinical trials
Below are recruiting azoospermia clinical trials, each written for real people, not researchers. We’re tracking 15 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02641769RecruitingPhase 1/Phase 2
Stem cell injection into testicles for infertility
This trial tests whether injecting your own stem cells into your testicles can help your body start producing sperm. It is for men whose infertility is caused by a sperm-making problem rather than a blockage.
Amman, Amman GovernorateAges 21–50 - NCT07008495Recruiting
Fertility surgery for men with varicocele and no sperm in ejaculate
This trial tests if fixing a varicocele (an enlarged vein in the scrotum) helps men who have no sperm in their ejaculate. The goal is to see if sperm can then be retrieved directly from the testicle for use in fertility treatments.
Qina, South ValleyAges 20–60 - NCT05479474Recruiting
PRP treatment study for men with testicular infertility
This trial studies whether platelet-rich plasma (PRP) can improve fertility in men with a specific cause of infertility called NOA who have not had success with prior procedures. It may help improve the chance of getting usable sperm for conception.
Stanford, CaliforniaAges 18 years+ - NCT06941922Recruiting
Testicular ultrasound study for men with no sperm
This study uses a special ultrasound to look at the testicles of men who have no sperm in their semen. It helps doctors understand how well this ultrasound can find sperm, which may help men with fertility problems.
Rockville, MarylandAges 18 years+ - NCT07357701Recruiting
Genetic study for unexplained infertility in men and women
This study aims to find genetic causes of certain types of infertility in men and women. If you have been diagnosed with very low sperm count, no sperm, or early ovarian failure, researchers will look at your DNA to discover new genes that might be responsible.
Bethesda, MarylandAges 18–100 - NCT02418832Recruiting
Sperm aspiration test for men with no sperm in semen
This study looks at a procedure that removes sperm directly from the testicles to help with IVF when a man has no sperm in his ejaculate. It may help couples try for pregnancy when standard semen samples don’t contain sperm.
JerusalemAges 16–80 - NCT03991663Recruiting
Study of treatment options for men with no sperm
This trial is for men who have repeatedly tested with no sperm found in their semen under a microscope. The study aims to understand or test options that may help people with this condition.
Zhengzhou, HenanAges 18–40 - NCT05628987Recruiting
Gut bacteria study in men with sperm production problems
This trial looks at whether gut bacteria (microbiome) and lifestyle factors are linked to poor sperm production or sperm quality. You may be asked for stool, urine, and blood samples and to complete questionnaires about diet and habits to help researchers understand possible connections.
Guangzhou, GuangdongAges 18–45 - NCT07691827Recruiting
Study of sperm problems linked to inherited genetic mutation
This study is investigating a specific genetic mutation in the MT-ND1 gene that can be passed from mother to son and may cause sperm production problems. It compares men with severe sperm issues to those with normal sperm production to understand the genetic cause.
Guangzhou, GuangdongAges Any age - NCT06841328Recruiting
Stem cell therapy for fertility in ovaries and testes
This study tests a regenerative stem cell therapy to improve fertility in men with testicular failure or low sperm count and women with early ovarian failure. It is for people who have already tried standard treatments without success.
Dubai, DubaiAges 20–50 - NCT06869863RecruitingPhase 1/Phase 2
Study of MediReg® for severe male infertility
This study tests an experimental medicine called MediReg® for men with severe infertility who have not been able to conceive. It aims to see if the drug is safe and can improve sperm quality, possibly offering a new option for men who have not had success with other treatments.
Moscow, MoscowAges 21–60 - NCT07074015Recruiting
AI tool to find sperm in surgery samples for male infertility
This study tests an artificial intelligence tool that helps doctors find very rare sperm in tissue removed during sperm retrieval surgery. If you have non-obstructive azoospermia (no sperm in your semen) and are having micro-TESE surgery, the AI might help find sperm that standard methods miss.
Boston, MassachusettsAges 18 years+ - NCT07542626Recruiting
Restoring Fertility by Transplanting Frozen Testicular Tissue
This trial tests whether transplanting frozen testicular tissue that was saved before cancer treatment can help men who cannot produce sperm have biological children. The tissue is thawed and put back into the testicles to restore natural sperm production.
BrusselsAges 18–40 - NCT07669584RecruitingPhase 2/Phase 3
Testing PKB171 for mild male infertility in couples
This study tests a new oral medication (PKB171) compared to a placebo for couples who have mild male infertility and have not tried IVF/ICSI before. The goal is to see if PKB171 can help them conceive naturally.
Pamplona, NavarreAges 18–38 - NCT07481370Enrolling by invitationPhase 2
Comparing Two Medicines for Male Infertility
This study tests two medicines—isotretinoin and human chorionic gonadotropin (hCG)—to see if they can improve sperm production in men with low sperm counts or no sperm due to certain causes. It might help if you haven't responded to other treatments before.
Omaha, NebraskaAges 19–50
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Common questions
- Are there clinical trials for azoospermia?
- Yes. Clin2 currently lists 15 recruiting azoospermia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a azoospermia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a azoospermia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.