Clinical trials
Lower Back Pain clinical trials
Below are recruiting lower back pain clinical trials, each written for real people, not researchers. We’re tracking 126 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04704297RecruitingPhase 4
Trigger point shots for low back muscle pain
This trial tests whether injecting sore “trigger points” in low back muscles helps improve chronic low back pain. It compares treatments in people with specific low back muscle pain patterns and excludes several other causes of pain.
Tacoma, WashingtonAges 18 years+ - NCT07766200Recruiting
Pain types in people with long-term low back pain
This study looks at different types of chronic low back pain. It aims to understand how pain affects people differently, which might help improve future treatments.
Kütahya, TürkiyeAges 18–70 - NCT07762170RecruitingPhase 4
Steroid injections for back and pelvic pain
This study is testing how well and how safely steroid injections work for different types of back pain. If you join, you'll receive the injection as part of your care and fill out surveys about your pain and ability to do daily activities before and after.
Thornhill, OntarioAges 18 years+ - NCT07652944Recruiting
Magnetic field therapy for chronic lower back pain
This trial tests whether magnetic fields applied to your back can relieve chronic lower back pain that has lasted at least 12 weeks. It's for people aged 18 to 64 who are willing to attend all study visits.
Edwards Air Force Base, CaliforniaAges 18–64 - NCT07641504RecruitingPhase 2
Testing LY4065967 for chronic low back pain relief
This study tests whether a new medication called LY4065967 can reduce chronic low back pain. Researchers want to see if it works better than current treatments for people who have had lower back pain for at least 3 months.
Birmingham, AlabamaAges 18 years+ - NCT07615816Recruiting
Medical massage therapy for active-duty service members with recent lower back pain
This study tests whether massage therapy can help active-duty service members who have had lower back pain for 1–3 months. Researchers want to see if massage reduces pain and improves function.
Joint Base Lewis McChord, WashingtonAges 18–64 - NCT07587047RecruitingPhase 1
Stem cell study for chronic lower back pain
This study tests a stem cell treatment for people with ongoing lower back pain. It aims to see if the therapy can help reduce pain and improve your quality of life.
Winter Park, FloridaAges 18–85 - NCT07579182RecruitingPhase 1
How Exercise and Hormones Affect Pain in Women
This study looks at how exercise affects pain and hormone levels in women. Researchers will ask you about your activity level, do some physical tests, and measure how your body responds to exercise over several visits.
Houston, TexasAges 18–60 - NCT07567300Recruiting
Understanding Pain Patterns in Migraine and Neck or Back Pain
This study explores how migraine headaches, neck pain, and lower back pain may share similar pain mechanisms in the body. Researchers will ask you questions to understand your pain patterns and help identify connections between these conditions.
Gaziantep, MerkezAges 18–65 - NCT07555496Recruiting
Back Pain Treatment After Spine Surgery: Injection vs. Needling
This study compares two ways to treat long-lasting back pain in people who have had spine surgery: injections into the back muscles versus dry needling (inserting thin needles into tight muscles). Both are combined with physical therapy to see which helps reduce pain better.
St-MaloAges 18 years+ - NCT07543835Recruiting
Yoga and Yoga Nidra for Chronic Low Back Pain
This study compares two types of yoga practices—traditional yoga and a deep relaxation technique called Yoga Nidra—to see which works best for chronic low back pain. You'll attend sessions over several weeks and track how your pain changes.
Orlando, FloridaAges 18–65 - NCT07535047Recruiting
How Placebo and TENS Work Together for Lower Back Pain
This study tests whether the expectation of pain relief (the placebo effect) can make a device called TENS (transcutaneous electrical nerve stimulation) work better for acute lower back pain. TENS uses gentle electrical pulses on your skin to reduce pain.
Giza, Giza GovernorateAges 18–65 - NCT07536672Enrolling by invitation
Understanding Pain and Sexual Health in Chronic Pain
This study helps develop a questionnaire (survey) that measures how chronic pain affects sexual health and relationships. If you have long-term pain and a stable relationship, your feedback could help doctors better understand and support patients like you.
Kütahya, KütahyaAges 18 years+ - NCT06696300Recruiting
Breathing muscle training for chronic low back pain
This study tests whether training the muscles you use to breathe can help reduce chronic low back pain. You will practice specific breathing exercises and see if they improve your pain and function.
Kırşehir, CenterAges 18–65 - NCT07496099Recruiting
Comparing two muscle-release therapies for low back pain
This study compares two types of gentle muscle-release techniques—post-isometric relaxation and myofascial release—to see which better relieves low back pain caused by lower cross syndrome, a common muscle imbalance. If you have ongoing back pain and tight hamstrings, this trial may offer a drug-free treatment option.
Karachi, SindhAges 18–45 - NCT07463729Recruiting
Back pain study using biofeedback training
This trial tests a stabilization training program using biofeedback (a device that shows you how your muscles are working) to treat chronic low back pain. It may help you strengthen the muscles supporting your spine and reduce your pain.
Tarnów, MałopolskaAges 30–65 - NCT07392333Recruiting
Nerve ablation for chronic low back pain
This study tests a treatment that uses radiofrequency energy to target specific nerves in the spine that may be causing your low back pain. If you qualify, you would receive the OptaBlate BVN procedure and be followed over time to see how well it works.
Fort Lauderdale, FloridaAges 22 years+ - NCT07334288Recruiting
Numbing injection for pain relief after lower back surgery
This study tests a numbing injection near the spine (retrolaminar block) to reduce pain after lower back surgery with hardware. It could help you use less pain medicine and recover more comfortably.
Santiago, Santiago MetropolitanAges 18–80 - NCT07339631RecruitingPhase 1
Sodium Aescinate for Chronic Low Back Pain in Adults
This study tests an injectable medication called sodium aescinate (derived from horse chestnut) for people with chronic low back pain. It aims to see if it helps reduce pain and is safe to use.
Xi'an, ShaanxiAges 18–65 - NCT07309731Recruiting
Hot vs. cold radiofrequency for chronic low back pain from facet joints
This trial compares two types of radiofrequency treatment (cooled vs. thermal) to see which works better for chronic pain coming from the small joints in your lower back. It is for people who have had back pain for at least 3 months and haven't gotten enough relief from usual treatments like pain medicine or physical therapy.
Zagazig, ElsharqyaAges 30–70 - NCT07278570Recruiting
Tracking muscle stiffness with MRI during hands-on therapy for low back pain
This study uses a special MRI scan to see if hands-on therapy (manual therapy) helps reduce muscle stiffness and pain in people with chronic low back pain. It aims to find a better way to measure how well this treatment works.
Rochester, MinnesotaAges 18 years+ - NCT07197879Recruiting
Does dynamic sitting prevent pain in office workers?
This study tests if a special swivel mechanism for office chairs can reduce or prevent back pain in people who sit a lot at work. It is for office workers who already develop pain during prolonged sitting.
Linz, Upper AustriaAges 18–65 - NCT07198412Recruiting
Study on sedation's effect on back pain after spinal anesthesia
This study looks at whether giving sedation (medicine to help you relax) during spinal anesthesia can reduce back pain after surgery. It's for people having certain types of surgery on their lower abdomen or legs.
Banhā, Qalyubia GovernorateAges 18–65 - NCT07178561Recruiting
Exercise for older adults with chronic back pain and anxiety
This study tests whether a supervised exercise program can reduce disability and improve mental health in older adults with chronic low back pain, poor sleep, and mild to moderate anxiety or depression.
Gaza, Gaza StripAges 55–70
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Common questions
- Are there clinical trials for lower back pain?
- Yes. Clin2 currently lists 126 recruiting lower back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lower back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lower back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.