Clinical trials
Bipolar Disorder clinical trials
Below are recruiting bipolar disorder clinical trials, each written for real people, not researchers. We’re tracking 184 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06560957Recruiting
Timed eating for bipolar depression study
This study tests if a timed eating schedule (eating within a set window each day) can help improve depression symptoms in people with bipolar disorder. The goal is to see if this eating pattern can stabilize mood and energy.
Ottawa, OntarioAges 18–55 - NCT06229210RecruitingPhase 3
Lumateperone safety study for children with schizophrenia, bipolar, or autism
This trial tests a medication called lumateperone for children and teens with schizophrenia, bipolar disorder, or autism spectrum disorder. It aims to see if the medicine is safe and tolerable over time.
Phoenix, ArizonaAges 5–17 - NCT06696755RecruitingPhase 2
Study of icalcaprant for bipolar depression
This study tests an oral medication called icalcaprant for adults with bipolar I or II who are currently in a depressive episode. The goal is to see if it reduces symptoms and whether it's safe when taken alongside your usual mood stabilizer.
Huntsville, AlabamaAges 18–65 - NCT06740331Recruiting
Thinking and memory study for mood disorders
This study looks at how people with bipolar disorder or depression process social situations, memory, and thinking. It compares patients, their relatives, and healthy volunteers to better understand these conditions.
ReimsAges 18–65 - NCT06740890RecruitingPhase 4
Exercise and a new medication for schizophrenia or bipolar disorder
This study tests whether a combination of a daily medication (olanzapine-samidorphan) and a structured exercise program can help people with schizophrenia, schizoaffective disorder, or bipolar disorder improve their health and well-being.
New York, New YorkAges 18–65 - NCT06804525Recruiting
Adapting a mental health survey in Hong Kong
This study adapts a mental health survey for Hong Kong adults. It is open to adults aged 25 and older who live in randomly selected households and can speak Chinese or English.
Hong KongAges 25 years+ - NCT06920940Recruiting
Ketogenic diet for bipolar disorder in teens
This study tests whether a ketogenic diet (a very low-carb, high-fat diet) can help teens with bipolar disorder who are currently feeling depressed or have mixed symptoms. Participants will receive medical and dietitian support while trying the diet for up to 12 weeks.
Los Angeles, CaliforniaAges 12–21 - NCT07031817Recruiting
Using a blood test to better diagnose bipolar disorder
This trial tests a new medical device that uses a blood test to help doctors accurately diagnose bipolar disorder in people who were thought to have major depression. It aims to see if the device can tell the difference and improve treatment choices.
MontpellierAges 18–65 - NCT07127913Recruiting
Closed-loop brain stimulation for hard-to-treat bipolar depression
This trial tests a closed-loop deep brain stimulation system for people with bipolar II disorder whose depression has not responded to standard treatments. The device sends targeted electrical pulses to the brain based on real-time activity, aiming to reduce depression symptoms.
San Francisco, CaliforniaAges 22–70 - NCT07172516RecruitingPhase 3
Study of azetukalner vs placebo for bipolar depression
This trial tests whether the study drug azetukalner can help reduce depression symptoms in people with bipolar I or II disorder who are currently having a depressive episode. You would be randomly assigned to receive either the drug or a placebo (inactive pill) to see which works better.
Tucson, ArizonaAges 18–74 - NCT07211217Recruiting
Time-restricted eating for bipolar depression
This study tests if eating only during a specific daily window can help with weight loss and mood in people with bipolar disorder who are currently depressed and overweight.
Boston, MassachusettsAges 18–65 - NCT07213466RecruitingPhase 4
Personalized weight-loss medication for bipolar disorder
This study wants to see if a personalized approach with FDA-approved weight-loss medications can help people with bipolar disorder who are overweight or have obesity, while staying on their mood stabilizer treatment. It might be a good fit if you have bipolar disorder and struggle with your weight.
Rochester, MinnesotaAges 18–65 - NCT07213492Recruiting
Support program for young adults with bipolar disorder
This study tests a program to help young adults with a recent bipolar diagnosis move from hospital back to their community. You would get education sessions and support from peers to make the transition smoother.
Hamilton, OntarioAges 18–35 - NCT07221864Recruiting
Emotions and brain activity in bipolar disorder
This study uses brain scans to understand emotions in bipolar disorder. It compares people with bipolar who are currently depressed or in a mixed state to healthy volunteers, and involves up to two visits to the research center.
Tulsa, OklahomaAges 18–65 - NCT07263191Recruiting
Olanzapine study for bipolar disorder
This study looks at how well patients with bipolar disorder do while taking the medication olanzapine. You will continue your regular treatment, and answer questions about your experience.
SeongnamAges 19 years+ - NCT07286175RecruitingPhase 2
Study of brenipatide for bipolar disorder
This trial tests an experimental drug called brenipatide for people with bipolar I or II disorder. It aims to see if the drug can help manage mood episodes when added to your current stable medications.
Orange, CaliforniaAges 18–75 - NCT07679204Recruiting
Personality and life satisfaction in bipolar and depression
This study looks at how personality traits and life satisfaction affect people with bipolar II disorder or major depression. You will fill out questionnaires about your feelings and daily life.
ElâzığAges 18 years+ - NCT07589647Recruiting
Brain Stimulation for Bipolar Disorder and Weight Management
This study tests whether a small electrical stimulation device targeting a specific brain region (the suprachiasmatic nucleus) can help improve metabolic health and weight in people with stable bipolar disorder who also have obesity. The goal is to see if this approach is safe and effective.
Hangzhou, ZhejiangAges 18–45 - NCT07622927Recruiting
Family conversations about bipolar disorder risk in youth
This study helps families talk about bipolar disorder when a parent or caregiver has it. Researchers are creating and testing a new tool to help young people understand their risk and recognize early warning signs, with the goal of getting help sooner if needed.
Dallas, TexasAges 7 years+ - NCT07217860Enrolling by invitationPhase 3
Long-term safety study of azetukalner for bipolar depression
This study is looking at the long-term safety of azetukalner for people with bipolar I or II depression who have already completed a previous trial of this drug. It is an open-label study, meaning everyone will receive the active medication.
Little Rock, ArkansasAges 18–75 - NCT07151846Enrolling by invitation
Using phone data to predict depression
This study uses your smartphone and a Fitbit to track mood patterns and see if they can predict depression. You may join as someone with a mood disorder, as a healthy volunteer, or as someone at higher risk for mood problems.
Seoul, Seongbuk-guAges 19–75 - NCT06011460Enrolling by invitation
Observing clozapine safety for bipolar depression
This study is testing whether clozapine, a medication usually used for schizophrenia, is safe for treating hard-to-treat depression in people with bipolar disorder. It may help if you have not found relief from other treatments.
Gdansk, Pomeranian VoivodeshipAges 18–65 - NCT07437833Recruiting
Self-regulation exercises for women with ADHD and stable bipolar disorder
This study tests how six different self-regulation techniques affect your body and brain during one session. It's designed for women with both ADHD and stabilized bipolar disorder who have been off psychiatric medications for at least two years.
PoznanAges 18–35 - NCT06560749Recruiting
Exercise to help thinking in bipolar disorder
This study tests whether a regular exercise program can help improve thinking and memory problems that often come with bipolar disorder. You must have stable mood and no recent changes to your medications.
São Paulo, São PauloAges 18–60
Hear when a new Bipolar Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for bipolar disorder?
- Yes. Clin2 currently lists 184 recruiting bipolar disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.