Clinical trials
Bipolar Affective Disorder clinical trials
Below are recruiting bipolar affective disorder clinical trials, each written for real people, not researchers. We’re tracking 59 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05480150Recruiting
Study of brain and mood in people with depression or bipolar disorder
This study is following and assessing people with major depression or bipolar disorder to better understand the condition and how the brain relates to symptoms. It may help researchers develop more targeted support by comparing brain and health information over time.
Hangzhou, ZhejiangAges 16–65 - NCT06197048Recruiting
Nutrition counseling for schizophrenia or bipolar disorder
This study tests whether nutritional counseling can improve body measurements and health markers in people with schizophrenia, psychosis, or bipolar disorder. It may help you manage weight and overall health.
Drammen, AkershusAges 18 years+ - NCT07858565Recruiting
Quality of life with quetiapine for schizophrenia or bipolar disorder
This study looks at how well patients feel and how safe it is when taking quetiapine alone or with other medicines for schizophrenia or bipolar disorder. It aims to help doctors understand the best ways to use this treatment.
SarajevoAges 18–65 - NCT07740694Recruiting
ECT study for older adults with depression
This study looks at how ECT affects brain activity and inflammation in older adults with depression. It may help researchers understand why ECT works and improve treatment.
Istanbul, BakırköyAges 55 years+ - NCT07472075RecruitingPhase 2
Melatonin vs placebo for bipolar disorder
This trial tests whether taking melatonin (a natural sleep hormone) helps stabilize mood in people with bipolar disorder compared to a placebo (a pill with no active ingredient). It may help improve sleep and mood stability.
FrederiksbergAges 18–70 - NCT07437833Recruiting
Self-regulation exercises for women with ADHD and stable bipolar disorder
This study tests how six different self-regulation techniques affect your body and brain during one session. It's designed for women with both ADHD and stabilized bipolar disorder who have been off psychiatric medications for at least two years.
PoznanAges 18–35 - NCT07412132RecruitingPhase 3
Testing lacosamide for hard-to-treat bipolar depression
This study tests if a medication called lacosamide can help people with bipolar depression that has not improved with at least two other treatments. It's for those with moderate to severe depression in bipolar I or II.
São Paulo, São PauloAges 18–65 - NCT07398365Recruiting
Medical study of psychiatry inpatients
This study looks at the medical and mental health patterns of adults admitted to general adult psychiatry wards. It aims to better understand their health needs.
Livingston, West LothianAges 18–65 - NCT07239778RecruitingPhase 2
PEDAL study: Reducing mood swings in bipolar disorder
This trial tests a smartphone-based program to help people with bipolar disorder manage rapid mood changes. It may help if you are interested in group support and using a mobile app.
DrammenAges 18–65 - NCT07221864Recruiting
Emotions and brain activity in bipolar disorder
This study uses brain scans to understand emotions in bipolar disorder. It compares people with bipolar who are currently depressed or in a mixed state to healthy volunteers, and involves up to two visits to the research center.
Tulsa, OklahomaAges 18–65 - NCT07213466RecruitingPhase 4
Personalized weight-loss medication for bipolar disorder
This study wants to see if a personalized approach with FDA-approved weight-loss medications can help people with bipolar disorder who are overweight or have obesity, while staying on their mood stabilizer treatment. It might be a good fit if you have bipolar disorder and struggle with your weight.
Rochester, MinnesotaAges 18–65 - NCT07151846Enrolling by invitation
Using phone data to predict depression
This study uses your smartphone and a Fitbit to track mood patterns and see if they can predict depression. You may join as someone with a mood disorder, as a healthy volunteer, or as someone at higher risk for mood problems.
Seoul, Seongbuk-guAges 19–75 - NCT06911931Recruiting
Visual perception study in schizophrenia and bipolar disorder
This study looks at how people with schizophrenia or bipolar disorder see the world. By comparing their visual perception to people without these conditions, researchers hope to learn more about how the brain processes what we see.
Rochester, New YorkAges 18–65 - NCT06904079Recruiting
AI-based rehab study for serious mental disorders
This study uses computer analysis and AI to predict how people with severe mental disorders might recover and to suggest better support. It may help improve rehabilitation plans tailored to each person.
ShanghaiAges 18–65 - NCT06831435Recruiting
Digital therapy for depression study
This study tests if a digital cognitive behavioral therapy program can help treat depression in real-world settings. It is designed for people aged 14 to 60 who have moderate to severe depression symptoms.
Beijing, Beijing MunicipalityAges 14–60 - NCT05802446Recruiting
Neurofeedback program for bipolar depression symptoms
This study tests whether “neurofeedback” can reduce leftover (residual) depressive symptoms in people with bipolar I or II. It may help calm mood by training brain activity, alongside stable medication.
Créteil, val-de-marneAges 18–65 - NCT06758414Recruiting
CBT for chronic pain in veterans with serious mental illness
This trial tests a type of talk therapy called Cognitive Behavioral Therapy for Chronic Pain, designed for veterans with serious mental illness. It aims to help you manage back pain and improve your quality of life.
Baltimore, MarylandAges 18 years+ - NCT06743711Recruiting
Heart fitness in severe mental illness study
This study checks how fit your heart and lungs are if you have a serious mental illness like schizophrenia or bipolar disorder. It aims to see if fitness can help improve health and well-being.
Glostrup MunicipalityAges 18–45 - NCT06740890RecruitingPhase 4
Exercise and a new medication for schizophrenia or bipolar disorder
This study tests whether a combination of a daily medication (olanzapine-samidorphan) and a structured exercise program can help people with schizophrenia, schizoaffective disorder, or bipolar disorder improve their health and well-being.
New York, New YorkAges 18–65 - NCT06706232RecruitingPhase 2
Psilocybin for Depression and Suicidal Thoughts in Bipolar II
This trial tests if two doses of psilocybin, given under medical supervision, are safe and acceptable for people with Bipolar II disorder who have mild to moderate depression and certain suicidal thoughts. The goal is to see if it may help improve mood and reduce suicidal thinking.
Houston, TexasAges 25–70 - NCT06560749Recruiting
Exercise to help thinking in bipolar disorder
This study tests whether a regular exercise program can help improve thinking and memory problems that often come with bipolar disorder. You must have stable mood and no recent changes to your medications.
São Paulo, São PauloAges 18–60 - NCT06529029RecruitingPhase 2/Phase 3
Comparing new low-pulse ECT to standard ECT for depression
This trial tests a new type of seizure therapy (low amplitude pulse seizure therapy) against the standard ultra-brief right unilateral ECT for people with severe depression, including those with suicidal thoughts. The goal is to see which treatment works better.
Grand Rapids, MichiganAges 18–90 - NCT06488573Recruiting
Nutrition program to improve heart health in bipolar disorder
This study tests if a nutrition program can help people with bipolar disorder improve their heart health. It is for adults aged 18 to 60 with bipolar I or II who are already on medication and are at moderate or high risk for heart problems.
São Paulo, São PauloAges 18–60 - NCT06229210RecruitingPhase 3
Lumateperone safety study for children with schizophrenia, bipolar, or autism
This trial tests a medication called lumateperone for children and teens with schizophrenia, bipolar disorder, or autism spectrum disorder. It aims to see if the medicine is safe and tolerable over time.
Phoenix, ArizonaAges 5–17
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Common questions
- Are there clinical trials for bipolar affective disorder?
- Yes. Clin2 currently lists 59 recruiting bipolar affective disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar affective disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar affective disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.