Clinical trials · Massachusetts
Blood Cancer clinical trials in Massachusetts
We’re tracking 22 recruiting blood cancer studies with a site in Massachusetts — including Early Phase 1, Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT07148180RecruitingPhase 1/Phase 2
Targeting leftover leukemia cells with a combination therapy
This trial tests a new drug combo (tagraxofusp, azacitidine, and venetoclax) for people with acute myeloid leukemia (AML) who have very small amounts of cancer cells still present after initial treatment. The goal is to see if it can clear these leftover cells and prevent the cancer from coming back.
Boston, MassachusettsAges 18 years+ - NCT06122077Recruiting
Blood test for early lung cancer detection in smokers
This trial tests a blood test that looks for multiple signals to find lung cancer early. If you are a smoker or former smoker over 50, this test might help detect cancer before you have symptoms.
Hyannis, MassachusettsAges 50 years+ - NCT07303816RecruitingPhase 4
Can statins prevent blood clots in cancer patients?
This trial tests whether a daily statin (rosuvastatin) can help prevent dangerous blood clots in people with advanced cancer who are starting new cancer therapy. It is for those at medium or high risk for clots, based on a simple risk score.
Boston, MassachusettsAges 18 years+ - NCT06469307Recruiting
Patient advisory board for inclusive cancer research
This study is about forming a community advisory board (a group of patients and researchers) to help make cancer research at Dana-Farber more inclusive and fair. It is not a treatment trial—instead, you would review study materials and give your perspective.
Boston, MassachusettsAges 18 years+ - NCT03779854RecruitingPhase 2
Preventing graft-versus-host disease in kids after stem cell transplant
This trial tests whether removing certain immune cells (T cells) from the donor transplant can lower the risk of chronic graft-versus-host disease (long-term immune attack after transplant) in children and young adults with blood cancers. If you qualify, it may help improve transplant outcomes while tracking safety and side effects.
Boston, MassachusettsAges 6 months–26 years - NCT05646576Recruiting
Palliative care support during blood cancer cell therapy
This trial studies whether adding palliative care (comfort-focused care to reduce stress and symptoms) helps people during adoptive cell therapy for blood cancers. It may help improve quality of life while you’re receiving the therapy.
Boston, MassachusettsAges 18 years+ - NCT06697184RecruitingPhase 1/Phase 2
Testing a slower start of sonrotoclax for blood cancers
This trial tests a new way to slowly increase the dose of the drug sonrotoclax when starting treatment for blood cancers like chronic lymphocytic leukemia (CLL) or mantle cell lymphoma (MCL). The goal is to see if this slower start is safer and better tolerated.
Boston, MassachusettsAges 18 years+ - NCT07226843RecruitingPhase 1
Study of a new drug for adults with certain blood cancers
This trial tests a new drug, LY4584180, for adults with several types of non-Hodgkin lymphoma who have already had at least two prior treatments. The goal is to see if the drug can help shrink tumors and stop the cancer from growing.
Boston, MassachusettsAges 18 years+ - NCT02474160Recruiting
Banking cancer tissue and blood for future research
This study collects and stores leftover or newly taken samples of tissue and blood from people with cancer. The goal is to build a research library that can help investigators study cancer and develop better tests or treatments.
Boston, MassachusettsAges 2 months+ - NCT03830320RecruitingPhase 1
PET scan to look for blood clots in the heart or lungs
This Phase 1 study uses a PET scan to detect blood clots (thrombosis) in specific groups of people. It’s testing how well the scan can find clots and how it should be timed with other heart or illness tests.
Boston, MassachusettsAges 18–85 - NCT00471978Recruiting
Analyzing DNA from blood and lung tumor tissue
This study looks at DNA from blood samples and lung tumor tissue in people newly diagnosed with primary lung cancer. The goal is to learn more about the cancer’s biology and possibly guide better future care.
Boston, MassachusettsAges 18–120 - NCT05334069Recruiting
Blood test study for early cancer detection in patients
This study collects blood from people with cancer and people without cancer (or with possible cancer) to test whether new blood tests can detect cancer earlier. Your blood samples help researchers evaluate how well these tests work.
Jamaica Plain, MassachusettsAges 40–75 - NCT04678401RecruitingPhase 1
Trial tests transplant using a half-matched donor for high-risk leukemia
This Phase 1 trial tests a special bone marrow transplant using a related “half-matched” donor (haploidentical), without a specific immune-suppressing medicine (“IS-free”). It’s for adults with certain high-risk AML or MDS to see if this approach can improve control of the disease while tracking safety.
Boston, MassachusettsAges 18–75 - NCT05410977Recruiting
Testing blood and stool for colon cancer in Lynch syndrome
This study collects blood and stool samples to see how well they can detect colorectal cancer or advanced growths in people with Lynch syndrome (an inherited colon cancer risk) or suspected Lynch syndrome. It may help find cancer or precancer earlier, which can improve next-step decisions.
Boston, MassachusettsAges 18 years+ - NCT05978141Recruiting
T-cell lymphoma registry study
This study creates a registry for people with certain T-cell or NK-cell lymphomas. It collects health information and tumor samples to learn more about these diseases and improve future treatments.
Boston, MassachusettsAges Any age - NCT06122896RecruitingEarly Phase 1
Screening for pancreatic cancer in high-risk people
This trial uses MRI and endoscopic ultrasound to look for early signs of pancreatic cancer in people who have a high risk due to their genes or family history. Finding it early may lead to better treatment options.
Boston, MassachusettsAges 18 years+ - NCT04794322Recruiting
Testing uterine fluid to help detect ovarian cancer
This study checks whether a sample of fluid from the uterus (uterine lavage) can help detect ovarian or fallopian tube cancer. You may join if you are having certain gynecologic surgeries or, in a smaller group, you have a BRCA1/2 mutation.
Boston, MassachusettsAges 30 years+ - NCT04712877Recruiting
Blood and tumor testing to choose the right lung cancer treatment
This trial tests tumor tissue and a blood sample to help doctors pick the most personalized treatment for people with suspected lung cancer. It may help ensure you get therapy matched to your specific tumor characteristics, especially when the cancer might be surgically removed.
Boston, MassachusettsAges Any age - NCT03689595Enrolling by invitation
PROMISE study: Predicting myeloma risk in high-risk groups
This study uses a blood test to find early signs of myeloma in people at higher risk, such as those with a family history or African ancestry. It aims to predict who might develop myeloma before symptoms appear.
Boston, MassachusettsAges 30 years+ - NCT04165798Recruiting
Pembrolizumab with or without chemotherapy for stage IV lung cancer
This trial tests whether pembrolizumab alone, or pembrolizumab plus chemotherapy, can treat stage IV non-small cell lung cancer. It may help shrink tumors and improve outcomes by boosting the immune system, with or without added chemotherapy.
Boston, MassachusettsAges 18 years+ - NCT03848962Recruiting
Share leftover or collected samples for research
This study helps collect and share human samples (like blood or other specimens) so researchers can do new studies. It’s mainly about providing samples for research use, not testing a treatment on you.
Lexington, MassachusettsAges 1 month–89 years - NCT05987241RecruitingPhase 2/Phase 3
Using a blood test to guide immunotherapy after bladder/kidney cancer surgery
This study tests whether a blood test that detects tumor DNA can help guide the use of immunotherapy (nivolumab with or without relatlimab) after surgery for urothelial cancer. The goal is to see if starting immunotherapy based on the blood test results can prevent the cancer from coming back.
Beverly, MassachusettsAges 18 years+
Blood Cancer trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting blood cancer studies listed above.
- Dana-Farber Cancer Institute · 14 studies
- Massachusetts General Hospital · 8 studies
- Brigham and Women's Hospital · 4 studies
- Beth Israel Deaconess Medical Center · 2 studies
- Addison Gilbert Hospital
- Beth Israel Deaconess Medical Center/Winchester Center for Cancer Care
- Beverly Hospital
- Boston Medical Center
What taking part in a blood cancer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Blood Cancer trials in other states
Common questions
- Are there blood cancer clinical trials in Massachusetts?
- Yes. We're currently tracking 22 recruiting blood cancer studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a blood cancer study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a blood cancer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New blood cancer studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.