Clinical trials
Bowel Disease clinical trials
Below are recruiting bowel disease clinical trials, each written for real people, not researchers. We’re tracking 275 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03571373Recruiting
Study of new childhood IBD and tracking safety
This trial collects information from children who are newly diagnosed with inflammatory bowel disease (IBD) and follows them to understand safety in real life. It may help doctors improve early diagnosis and treatment planning for kids with IBD.
RotterdamAges birth–19 years - NCT06871267Recruiting
Dietary changes for mild to moderate Crohn's disease
This study looks at how changing your diet might help people with Crohn's disease feel better. It is for adults with mild to moderate Crohn's who are not using a liquid-only diet and have not had recent surgery.
Kuala Lumpur, Petaling JayaAges 18–50 - NCT07242248Recruiting
Real-world study of guselkumab for Crohn's and colitis
This study looks at how well guselkumab works in real life for people with moderate-to-severe Crohn's disease or ulcerative colitis. It tracks patients in the UK who start guselkumab as part of their normal care.
HarrowAges 18 years+ - NCT02421705Recruiting
Brain-gut sensitivity study in IBS and inflammatory bowel disease
This study checks how sensitive your gut is to normal stimuli in people with IBS, ulcerative colitis, Crohn’s disease, and in healthy volunteers. Results may help researchers understand why some people feel more abdominal discomfort and how that connects to inflammatory bowel conditions.
Leuven, Vlaams-BrabantAges 18–65 - NCT04617184Recruiting
Join an inflammatory bowel disease registry and sample bank
This study asks people with known or suspected inflammatory bowel disease to enroll in a registry and biorepository. It helps researchers better understand the condition using health information and stored biological samples.
Austin, TexasAges 18–100 - NCT01140789Recruiting
Study comparing people with and without bowel inflammation
This study looks at people with inflammatory bowel disease (Crohn’s disease or ulcerative colitis) and compares them with people without it. Researchers want to understand differences that may help explain or better detect the disease.
Hong KongAges 18 years+ - NCT07300553RecruitingPhase 2
Gut bacteria and energy metabolism in health and IBD
This study looks at how the bacteria living in your gut affect your body's energy use. It includes both healthy volunteers and people with inactive Crohn's disease or ulcerative colitis.
ParisAges 18–50 - NCT07245394Recruiting
Switching to guselkumab for inflammatory bowel disease after ustekinumab
This trial tests whether switching from the drug ustekinumab to another drug called guselkumab can help people with active inflammatory bowel disease (IBD) who didn't get enough benefit from ustekinumab. It focuses on people with Crohn's disease or ulcerative colitis who still have signs of inflammation in their gut.
Calgary, AlbertaAges 18 years+ - NCT05733845Recruiting
Study of why some bowel inflammation treatments don’t work
This study looks at blood and/or tissue “molecular” (cell-level) reasons why treatments don’t fully work in adults with Crohn’s disease or ulcerative colitis. If you are starting a biologic or small-molecule medicine and still have moderate to severe symptoms, you may be able to contribute to research that helps improve future care.
Vandœuvre-lès-Nancy, CHRU de NancyAges 18 years+ - NCT07132333Recruiting
Personalized inflammation study for chronic conditions
This study uses advanced testing to understand inflammation in people with certain chronic inflammatory diseases, such as psoriasis, psoriatic arthritis, other types of arthritis, or inflammatory bowel disease. The goal is to tailor treatment to your specific needs.
TübingenAges 18 years+ - NCT06956703Recruiting
Nottingham IBD study testing new treatments
This study looks at people with active Crohn's disease or ulcerative colitis starting a new type of medication (anti-TNF, ustekinumab, upadacitinib, or vedolizumab), as well as people without IBD having a routine colonoscopy. It aims to collect information to better understand how these treatments work.
Nottingham, NottinghamshireAges 16 years+ - NCT04280510Recruiting
Study of immune-related gut illnesses in adults
This study looks at adults with immune-related stomach and intestine problems to better understand what may cause them. If you qualify, you can share information and consent to help researchers learn how these conditions work.
CréteilAges 18 years+ - NCT02636517Enrolling by invitationPhase 1
Fecal microbiome transplant for repeat C. difficile infection
This Phase 1 study tests whether transferring healthy gut bacteria (a fecal microbiome transplant) can help children with repeated or moderate-to-severe C. difficile infection. It focuses on changing gut bacteria to reduce ongoing infection and symptoms.
Philadelphia, PennsylvaniaAges 3–21 - NCT04751396Recruiting
Melanoma education for people with autoimmune conditions
This trial tests an educational tool to help people with melanoma and pre-existing autoimmune disease understand immune checkpoint inhibitor treatment. It aims to support you and your care team with information that can help you make decisions and feel more prepared.
Houston, TexasAges 18 years+ - NCT05387031Recruiting
Ustekinumab for painful Crohn’s bowel narrowing
This trial tests ustekinumab, a medicine that calms immune inflammation, to see if it can improve symptoms in people with Crohn’s disease that causes bowel narrowing. It may help if your Crohn’s symptoms come from strictures (narrowed areas) seen on scans or endoscopy.
Beijing, Beijing MunicipalityAges 18–65 - NCT06573723Recruiting
Rare disease registry at Hospital Italiano
This study collects information from patients with certain rare diseases to better understand them. If you have one of these conditions and receive care at Hospital Italiano de Buenos Aires, you may be able to join.
Buenos Aires, Buenos AiresAges Any age - NCT07632573RecruitingPhase 1
Safety Study of BDHK-2009 Tablets in Healthy Adults
This is an early-stage safety study testing a new experimental tablet called BDHK-2009 in healthy volunteers with no major illnesses. Researchers want to make sure the drug is safe and well-tolerated before testing it in people with medical conditions.
Hangzhou, ZhejiangAges 18–55 - NCT03953768Recruiting
Testing a new vagus nerve stimulator for gut and immune health
This study looks at what happens to your immune system and stomach/gut function after getting a vagus nerve stimulator (VNS) for the first time for epilepsy. It may help doctors understand whether the device benefits more than seizures.
Louisville, KentuckyAges birth–60 years - NCT07532213Recruiting
Real-world outcomes of guselkumab for ulcerative colitis or Crohn's disease
This study tracks how well guselkumab (a biologic medication that blocks IL-23, a protein that drives inflammation) works for moderate-to-severe ulcerative colitis or Crohn's disease in everyday clinical practice. Researchers want to understand long-term benefits and safety in real patients.
BernAges 18 years+ - NCT07377188Recruiting
Pregnancy and Inflammatory Bowel Disease Study
This trial looks at how pregnancy affects and is affected by inflammatory bowel disease. It aims to learn more to help women with IBD who are or want to become pregnant.
AmiensAges 18–50 - NCT07237516Recruiting
Study of Zymfentra for people with Crohn's or colitis
This study follows adults with inflammatory bowel disease who are starting or switching to Zymfentra. Researchers will track your health over the next year to see how the medicine works in real life.
New Haven, ConnecticutAges 18 years+ - NCT06774079RecruitingPhase 4
GLP-1 drug and diet study for Crohn's disease patients
This study tests a drug that helps with weight loss and blood sugar (called a GLP-1 receptor agonist) combined with a special diet to see if it can improve symptoms in people with mild Crohn's disease. You may join if you have Crohn's, a BMI of 27 or higher, and are already on a stable dose of a TNF blocker.
Miami, FloridaAges 18 years+ - NCT06065228Recruiting
Tracking treatment progress in children with IBD
This study looks at a new way to measure how well treatment is working in children with inflammatory bowel disease (IBD). It uses a special eye test called pupillometry, which is painless and non-invasive, to see if it can help doctors adjust treatment earlier.
Washington D.C., District of ColumbiaAges 6–21 - NCT05722236Recruiting
Peer support program to help people manage stress from IBD
This trial tests a “peer-to-peer” support program to help adults with inflammatory bowel disease (IBD) manage psychological distress (stress and emotional strain). It may help you cope better during major life or treatment changes related to IBD.
Halifax, N.S.Ages 18–99
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Common questions
- Are there clinical trials for bowel disease?
- Yes. Clin2 currently lists 275 recruiting bowel disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bowel disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bowel disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.