Clinical trials
Brain Diseases clinical trials
Below are recruiting brain diseases clinical trials, each written for real people, not researchers. We’re tracking 328 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02402426Enrolling by invitation
Online brain health registry for adults
This study is building an online registry where adults can share information to help researchers find people for future brain research. Joining may help future studies get the people they need.
San Francisco, CaliforniaAges 18 years+ - NCT05885295Recruiting
Testing thinking and memory after stroke using cognitive exams
This study looks at how thinking and memory change after a stroke using short cognitive tests. It may help researchers better understand which brain changes affect thinking, and how to measure them accurately.
LondonAges 18 years+ - NCT07319078Recruiting
Online treatment for kids with stomach pain
This study tests an internet-based program to help children and teens with certain long-term stomach conditions, like irritable bowel syndrome (IBS) or ongoing stomach pain. It aims to see if online tools can reduce symptoms and improve daily life.
StockholmAges 8–17 - NCT07115394Recruiting
Brain wave tracking during DBS for movement disorders
This study uses EEG (a non-invasive scalp recording) to measure brain signals while deep brain stimulation (DBS) is active. It aims to better understand how DBS affects brain activity in people with Parkinson's disease, essential tremor, or dystonia.
HamburgAges 35–85 - NCT07087951Recruiting
Sound therapy for memory loss in older adults
This study tests whether listening to a special sound (gamma-frequency tones) can help slow down memory loss in older adults. It's for people who have mild memory problems but not dementia or other brain disorders.
Taoyuan, GuishanAges 60 years+ - NCT07049094RecruitingPhase 4
Scalp nerve block for pain after brain surgery
This trial tests if a long-lasting numbing medicine (bupivacaine liposomes) injected into scalp nerves can reduce pain after brain surgery. It may help you need less pain medicine and feel better after your operation.
Hangzhou, ZhejiangAges 18 years+ - NCT06984757Enrolling by invitation
Brain waves and thinking in Parkinson's disease
This study looks at how brain activity relates to thinking and memory in people with Parkinson's disease, including those with and without cognitive issues, and those with deep brain stimulation. It uses EEG (a non-invasive brain wave recording) and sometimes mild brain stimulation (TMS or tACS) to understand these connections better.
Iowa City, IowaAges 18–99 - NCT07636720Recruiting
Sleep monitoring with Parkinson's deep brain stimulation device
This study uses a special sensing device in your existing Parkinson's deep brain stimulation implant to monitor your sleep patterns. Researchers want to understand how sleep and the stimulation device interact, which could help improve treatment for Parkinson's patients.
San Antonio, TexasAges 40–80 - NCT06207591Recruiting
Brain implant study for locked-in communication
This study tests a new brain implant (CortiCom) that may help people who are locked-in or nearly locked-in communicate again. It involves surgery to place the device in the brain and requires a caregiver and commitment to follow-up visits.
UtrechtAges 18–70 - NCT06111898Recruiting
Understanding movement in infants at risk
This study looks at how the brain and body work together to control movement in infants who are at high risk for developmental issues. It may help find early signs of motor problems.
GenevaAges 8 months–1 year - NCT07700862Recruiting
Deep brain stimulation for tremor-dominant Parkinson's disease
This trial compares two ways to place electrodes in the brain to reduce tremors. It may help people with Parkinson's disease whose main symptom is shaking.
ShanghaiAges 18–80 - NCT05423860Recruiting
HALO prostate study for men with early prostate cancer
This trial studies HALO, a new “human analytics” approach, in men with early-stage prostate cancer. It may help doctors better assess or guide care using MRI and biopsy findings, before or around initial treatment.
Indian Wells, CaliforniaAges 45–90 - NCT05336695RecruitingPhase 1/Phase 2
Brain scan study to measure fibrin in Alzheimer’s
This early study (Phase 1/2) uses brain imaging to look for “fibrin” (a blood-clot–related protein) in people with Alzheimer’s disease and related conditions. The goal is to understand whether fibrin changes can be seen on scans and what it might mean for Alzheimer’s.
Boston, MassachusettsAges 55–90 - NCT05241262RecruitingPhase 1
N-acetylcysteine for people with m.3243A>G and low brain glutathione
This trial tests whether the supplement N-acetylcysteine (NAC) can help people who have the m.3243A>G mitochondrial genetic change and low levels of a brain chemical called glutathione. The study aims to see if raising glutathione in the brain is safe and potentially beneficial for these patients.
New York, New YorkAges 18–80 - NCT05101161Recruiting
Neurofeedback delivered through implanted brain stimulation
This study tests a brain “feedback” approach using electrodes already placed as part of standard medical care. It aims to see whether this method is safe and helpful for people undergoing deep brain stimulation after surgery.
Zurich, Canton of ZurichAges 18 years+ - NCT05658302Recruiting
Deep brain stimulation for Parkinson’s, using targeted stimulation
This study is testing a specific approach to deep brain stimulation (DBS) for people with Parkinson’s disease who are getting DBS surgery as part of routine care. It may help doctors learn whether circuit-based, more targeted stimulation is safe and useful for Parkinson’s symptoms.
Minneapolis, MinnesotaAges 21 years+ - NCT03021031Enrolling by invitation
Deep brain stimulation for Parkinson’s patients
This trial studies a type of brain stimulation to help reduce symptoms in people with Parkinson’s disease. You may be able to join if you have Parkinson’s and are being considered for this treatment.
Minneapolis, MinnesotaAges 21 years+ - NCT06874231Recruiting
Brain connectivity marker for Alzheimer's disease
This study uses brain scans to find a marker for Alzheimer's disease. It is looking for people with normal memory, mild memory problems, or mild Alzheimer's, and who can undergo a spinal tap and MRI.
Stockholm, SolnaAges 40–85 - NCT05443906Recruiting
Home exercise program for people with neurodegenerative conditions
This trial studies whether a home exercise program is safe and helpful for people with certain neurodegenerative conditions, including X-linked adrenoleukodystrophy and DARS2-related disease, as well as some other similar diagnoses. You would be asked to do exercises at home and be assessed on your walking and strength/safety.
Baltimore, MarylandAges 5–75 - NCT05182892Recruiting
Reducing speech side effects from DBS using speech recordings
This study tests whether automated analysis of your speech can help reduce speech problems caused by deep brain stimulation (DBS) in Parkinson’s disease. It may help your team adjust DBS settings to improve how you speak while keeping Parkinson symptoms controlled.
PragueAges 18 years+ - NCT06939465Recruiting
Cognitive therapy for throat and chest symptoms
This trial tests if a cognitive-behavioral therapy (a type of talk therapy that helps change thoughts and habits) can improve chronic throat and chest symptoms like heartburn, reflux, lump in throat, or trouble swallowing. It is for people who have these symptoms without a known structural problem in the esophagus.
Hualien CityAges 18–75 - NCT06778824Recruiting
Brain-gut medicine trial for chronic esophagus issues
This trial tests a type of brain-gut medicine to see if it helps with ongoing esophagus problems like heartburn, acid reflux, a lump in the throat, trouble swallowing, or chest pain. It might help if other treatments haven't worked well.
Hualien CityAges 18–75 - NCT06339398Recruiting
Exercise dose and brain health in Parkinson's
This study looks at how different amounts of physical exercise affect brain chemicals, movement symptoms, and brain connections in people with Parkinson's disease. You would walk and do exercises while researchers track changes over time.
Cassino, FrosinoneAges 30–80 - NCT07553338RecruitingPhase 2
Leronlimab Safety and Brain Inflammation in Alzheimer's
This study tests whether a drug called leronlimab is safe and can reduce inflammation in the brains of people with mild-to-moderate Alzheimer's disease or memory problems. Researchers will use special brain scans to see if the drug affects inflammation.
New York, New YorkAges 50 years+
Hear when a new Brain Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for brain diseases?
- Yes. Clin2 currently lists 328 recruiting brain diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.