Clinical trials
Brain Diseases clinical trials
Below are recruiting brain diseases clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06778824Recruiting
Brain-gut medicine trial for chronic esophagus issues
This trial tests a type of brain-gut medicine to see if it helps with ongoing esophagus problems like heartburn, acid reflux, a lump in the throat, trouble swallowing, or chest pain. It might help if other treatments haven't worked well.
Hualien CityAges 18–75 - NCT06939465Recruiting
Cognitive therapy for throat and chest symptoms
This trial tests if a cognitive-behavioral therapy (a type of talk therapy that helps change thoughts and habits) can improve chronic throat and chest symptoms like heartburn, reflux, lump in throat, or trouble swallowing. It is for people who have these symptoms without a known structural problem in the esophagus.
Hualien CityAges 18–75 - NCT05993364Recruiting
EFA treatment for brain injury recovery
This trial tests a treatment called EFA for people recovering from a brain injury (from trauma or stroke). It aims to help patients who are still in the early stages of recovery and can breathe on their own during the day.
Rovato, BSAges 18 years+ - NCT06339398Recruiting
Exercise dose and brain health in Parkinson's
This study looks at how different amounts of physical exercise affect brain chemicals, movement symptoms, and brain connections in people with Parkinson's disease. You would walk and do exercises while researchers track changes over time.
Cassino, FrosinoneAges 30–80 - NCT07553338RecruitingPhase 2
Leronlimab Safety and Brain Inflammation in Alzheimer's
This study tests whether a drug called leronlimab is safe and can reduce inflammation in the brains of people with mild-to-moderate Alzheimer's disease or memory problems. Researchers will use special brain scans to see if the drug affects inflammation.
New York, New YorkAges 50 years+ - NCT06715995Recruiting
Light stimulation's effect on brain waves in healthy older adults
This trial tests if a special light (gamma light) can change brain wave patterns in healthy adults over 55. It aims to understand how light might help keep the brain sharp.
Taoyuan, GuishanAges 55 years+ - NCT06906276Recruiting
Brain activity during walking in atypical Parkinson's
This study looks at brain activity while walking in people with atypical Parkinsonian syndromes like PSP or MSA. It may help understand how these conditions affect walking and balance.
Solna, SolnaAges Any age - NCT03418441Recruiting
Study infections of the brain and spinal fluid in Denmark
This trial focuses on people in Denmark who may have an infection in the brain or the fluid around the brain and spinal cord. Researchers aim to collect and compare diagnostic results for different infection types (viral meningitis, bacterial meningitis, encephalitis, and others) to help confirm the cause and guide care.
AalborgAges 18 years+ - NCT04061135Recruiting
Study brain and movement patterns in Parkinson’s or tremor
This study looks at brain signals, thinking, and movement behaviors in people who have Parkinson’s disease or essential tremor and are being considered for deep brain stimulation (DBS) surgery. It may help researchers better understand how DBS affects the brain and day-to-day function.
Birmingham, AlabamaAges 18 years+ - NCT04322734Recruiting
Blood tests study immune and metabolism markers in neurodevelopment
This study looks for biological “signals” in blood—related to the immune system and metabolism—to better understand conditions like autism and other brain or development-related disorders. It may help researchers find markers that could guide future diagnosis or treatment.
Phoenix, ArizonaAges Up to 18 years - NCT04426786Recruiting
Exercise study to improve brain energy in Parkinson’s
This trial tests whether a structured exercise program can change how your brain uses energy in Parkinson’s disease. It may help improve symptoms or brain-related measures, especially in people who currently exercise very little.
Vancouver, British ColumbiaAges 40–80 - NCT05292794Recruiting
CereGate therapy for freezing of gait in Parkinson’s
This trial tests whether CereGate therapy can reduce “freezing of gait,” a walking problem, in people with Parkinson’s disease who already have deep brain stimulation (DBS). If you meet the device and medication stability requirements, the study may help your walking and movement symptoms measured during testing.
Redwood City, CaliforniaAges 21–80 - NCT05892510RecruitingPhase 2/Phase 3
Tenecteplase after clot removal for no-reflow stroke
This trial tests whether giving tenecteplase directly into the brain artery after a thrombectomy can improve outcomes when blood flow doesn’t fully return (“no-reflow”) in an emergency stroke. It may help some people by reducing ongoing clot-related blockage after the main clot is removed.
Gold Coast, QueenslandAges 18 years+ - NCT06183658Recruiting
Healthy Brain Aging Study for Adults 55–90
This study looks at healthy brain aging in older adults. It involves brain scans, blood tests, and regular check-ins to understand how memory and thinking change over time.
Shenzhen, OtherAges 55–90 - NCT06320132Recruiting
Study on brain bleed recovery in the ICU
This study looks at how patients recover after a sudden, non-traumatic brain bleed. It aims to learn more about their brain function and daily living skills over time.
Milan, MIAges 18 years+ - NCT06716489Recruiting
Exercise study for women with migraine
This study tests whether aerobic exercise can help reduce migraine symptoms and improve how your body senses and responds to pain. It is specifically for women aged 18–48 who have migraine headaches 3–8 days per month.
Ribeirão Preto, São PauloAges 18–48 - NCT07071350RecruitingPhase 2/Phase 3
Optimizing heart rate for persistent concussion symptoms in military veterans
This trial tests a treatment designed to improve heart rate variability, which may help reduce long-term concussion symptoms like headaches, dizziness, and trouble sleeping. It is for military veterans who have had a mild concussion more than a year ago and still have ongoing symptoms.
Richmond, VirginiaAges 18 years+ - NCT00585572Enrolling by invitation
Wisconsin Brain Donor Program for research after death
This program collects donated brain tissue and related samples after death to help researchers study brain diseases. You may be eligible if you’re an approved family member of a specific study participant, or you meet certain health and consent requirements.
Madison, WisconsinAges 18 years+ - NCT07455760Recruiting
Deep brain stimulation and speech sequencing study
This study looks at how deep brain stimulation affects speech in people with Parkinson's disease or essential tremor. It tests whether the stimulation changes the way you say sequences of sounds.
Boston, MassachusettsAges 18 years+ - NCT07099859RecruitingPhase 4
Losartan after aortic valve surgery for severe leakage
This trial tests if the drug losartan can help the heart recover better after surgery to replace a leaky aortic valve. It may reduce strain on the heart and improve long-term outcomes.
São Paulo, São PauloAges 18–85 - NCT04740580RecruitingEarly Phase 1
Test glutathione for brain inflammation in Alzheimer’s
This early-stage study tests whether taking glutathione can affect brain “inflammation” and metabolism in people with Alzheimer’s disease. You might benefit from a new treatment approach, while helping researchers understand what works best for early Alzheimer’s-related brain changes.
Houston, TexasAges 55–85 - NCT05667649RecruitingPhase 1
Stem cells injected in brain for mild to moderate Alzheimer’s
This Phase 1 study tests whether injecting your own (autologous) activated fat-derived stem cells into the brain is safe and potentially helpful for mild to moderate Alzheimer’s disease. The goal is to see how the treatment affects the brain and symptoms, using cells made from your own donated fat tissue.
Newport Beach, CaliforniaAges 45–80 - NCT06329726Recruiting
Thinking and memory after brain stimulation for Parkinson's
This study looks at how deep brain stimulation (DBS) affects thinking and memory in people with Parkinson's disease over time. It compares results from people who have DBS and those who receive only medication.
Milan, LombardyAges 18–70 - NCT07299279Recruiting
Exercise for Brain Health in Parkinson's
This trial studies whether a physical activity program can improve brain health and thinking skills in people with Parkinson's disease who also have mild cognitive impairment. It is designed for those who are not already very active.
Roma, RomeAges 30–80
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Common questions
- Are there clinical trials for brain diseases?
- Yes. Clin2 currently lists 336 recruiting brain diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.