Clinical trials
Brain Diseases clinical trials
Below are recruiting brain diseases clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03664609Recruiting
Study of outcomes for people with deep brain stimulation
This study looks back at results for people who have already had deep brain stimulation (DBS) or could get it. It aims to understand how DBS is used and what outcomes people experience.
Phoenix, ArizonaAges Any age - NCT05847985Recruiting
Noninvasive brain stimulation for thinking and language issues
This study tests whether a noninvasive brain stimulation treatment can improve sentence understanding in people with Parkinson’s disease–related mild cognitive impairment or mild cognitive impairment from Lewy body disease. It also compares results with healthy volunteers who do not have Lewy body or other memory/brain disorders.
BrnoAges 60–80 - NCT06837272Recruiting
Gut health and brain health in Alzheimer's disease
This study looks at how the bacteria in your gut might be connected to memory and thinking problems in Alzheimer's disease. It may help us understand if changes in the gut can affect brain health.
Jining, ShandongAges 60–80 - NCT07127510Recruiting
Brain NAD in Alzheimer's disease study
This study tests whether a natural substance called NAD can improve brain health in people with early Alzheimer's. You may be eligible if you have a firm Alzheimer's diagnosis, are between 65 and 80, and can walk and talk without help.
Boca Raton, FloridaAges 65–80 - NCT07157345RecruitingPhase 1
Testing PDR-001 for Parkinson's Disease
This trial tests a new drug, PDR-001, to see if it can safely remove harmful proteins from the brain in people with early Parkinson's disease. It may help slow down the disease.
Shanghai, Shanghai MunicipalityAges 40–65 - NCT07434089Recruiting
Walking therapy and gut health in Parkinson's
This trial tests how a special treadmill (C-Mill) training affects the connection between your brain and gut in Parkinson's disease. It may help improve walking and gut symptoms.
Messina, MessinaAges 40–70 - NCT07567664Enrolling by invitation
Brain Changes in Neurodegenerative Diseases: A Tracking Study
This research study tracks how brain damage progresses in rare neurodegenerative diseases like frontotemporal dementia, primary progressive aphasia, PSP, CBS, and ALS. Researchers use brain imaging and tests to understand how these diseases spread in the brain, which could help develop better treatments.
Milan, LombardyAges 20–85 - NCT06860828Enrolling by invitation
Football players and brain health study: DIAGNOSE CTE
This study looks at brain changes in former college and professional football players, people with memory problems, and healthy controls. It aims to learn more about chronic traumatic encephalopathy (CTE) and Alzheimer's disease.
Phoenix, ArizonaAges 50 years+ - NCT05070013Recruiting
Brain stimulation to improve sleep in people with Parkinson’s disease
This study tests an adaptive brain stimulation device to help restore better sleep in people with Parkinson’s disease. You may be eligible if your Parkinson’s motor symptoms are severe despite best medical treatment and you are already being considered for a specific deep brain stimulation surgery.
Omaha, NebraskaAges 18–80 - NCT06041659Recruiting
Brain network changes during moyamoya bypass surgery
This study uses MRI scans to watch how brain networks work while you are asleep during moyamoya bypass surgery. It may help doctors understand how the brain adjusts after the procedure.
Beijing, Beijing MunicipalityAges 18–65 - NCT06792877Recruiting
Mindfulness for thinking in early Alzheimer's
This study tests if mindfulness training can help protect thinking and memory in early-stage Alzheimer's disease. It compares mindfulness to other activities to see if it slows down memory loss.
Boston, MassachusettsAges 50–100 - NCT07374913Recruiting
Study of COL4A1 and COL4A2 gene mutations
This study looks at people with a mutation in the COL4A1 or COL4A2 genes, which can cause problems in small blood vessels throughout the body. It aims to learn more about the condition and may also include family members who carry the mutation or who can serve as healthy controls.
Florence, FIAges Any age - NCT07476781Recruiting
Liquid biopsy study for solid tumours and brain tumours
This study collects samples of spinal fluid and blood from people with solid tumours that have spread to the brain or spine, or who have primary brain tumours. The goal is see if these samples can help doctors detect and monitor these cancers more easily.
Toronto, OntarioAges 18 years+ - NCT04681534Recruiting
Testing safer adaptive deep brain stimulation for Parkinson’s
This trial studies an “adaptive” form of deep brain stimulation (DBS) that adjusts based on brain signals, and is mainly done when the DBS battery (IPG) needs replacement or when people are getting DBS for the first time. It aims to improve safety and effectiveness for Parkinson’s symptoms by using recorded brain activity during treatment.
MilanAges Any age - NCT06090201Recruiting
Brain health study for severe bleeding disorders
This study uses brain scans and thinking tests to understand how severe hemophilia or von Willebrand disease affects the brain and memory over time.
LilleAges 18 years+ - NCT06197698Recruiting
Parkinson's and gut-brain connection study
This study is looking at how the bacteria in your gut might affect your brain in Parkinson's disease. It involves two types of brain scans to see differences between people with Parkinson's and healthy volunteers.
DouliuAges 20 years+ - NCT06241482Recruiting
Enhanced recovery after brain surgery in intensive care
This study tests a special recovery program for people with serious brain injuries or strokes who need intensive care. The program focuses on helping you heal faster after surgery.
ShanghaiAges 18–75 - NCT06352710Recruiting
Tracking recovery after brain or spine surgery
This study uses a smartphone app to track how you recover after brain or spine surgery. It helps doctors understand how side effects affect your daily life, so they can improve care.
Sankt Gallen, St.GallenAges 18 years+ - NCT06689410Recruiting
Brain aneurysm research registry and biobank
This study is collecting medical information and samples from people with brain aneurysms to learn more about the condition. If you have a recently found aneurysm, you may be able to help researchers understand how aneurysms form and how to better treat them in the future.
Nantes, Loire-AtlantiqueAges 18 years+ - NCT06953232Recruiting
Protein drink for heart and brain in midlife women
This study tests a special protein drink (whey with milk fat globule membrane) to see if it helps your heart and brain after a high-fat breakfast. It might help you if you are a postmenopausal woman at moderate risk for heart disease.
Loughborough, LeicestershireAges 50–75 - NCT07284784RecruitingPhase 2/Phase 3
Buntanetap for Parkinson's disease study
This trial tests an investigational drug called buntanetap in people with Parkinson's disease. It aims to see if the drug can improve symptoms. There are two groups: those who've taken buntanetap before (Cohort 1) and those with a deep brain stimulator (DBS) implant for at least a year (Cohort 2).
Birmingham, AlabamaAges 40–85 - NCT02553525Enrolling by invitation
Testing different stimulation patterns in Parkinson’s, tremor, and MS
This study tests whether changing the “stimulation pattern” in a deep brain stimulator can improve how well symptoms are controlled. If you are already getting (or replacing) a deep brain stimulator, this may help fine-tune the settings for you.
Gainesville, FloridaAges 21–80 - NCT06618157Enrolling by invitation
Brain stimulation study for Parkinson's tremor
This study tests a new way to adjust deep brain stimulation (DBS) for Parkinson's disease. It focuses on people who still have at least mild tremor after their DBS device has been in place for three months or more, to see if targeting specific brain connections can help improve tremor control.
Durham, North CarolinaAges 18 years+ - NCT07682311Recruiting
Adjusting brain stimulation automatically for Parkinson's
This study tests a new way to adjust deep brain stimulation (DBS) automatically during the day to better control Parkinson's symptoms. It is for people who already have a Percept DBS device but still have motor fluctuations.
San Francisco, CaliforniaAges 25–75
Hear when a new Brain Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for brain diseases?
- Yes. Clin2 currently lists 336 recruiting brain diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.