Clinical trials
Brain Diseases clinical trials
Below are recruiting brain diseases clinical trials, each written for real people, not researchers. We’re tracking 328 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06860828Enrolling by invitation
Football players and brain health study: DIAGNOSE CTE
This study looks at brain changes in former college and professional football players, people with memory problems, and healthy controls. It aims to learn more about chronic traumatic encephalopathy (CTE) and Alzheimer's disease.
Phoenix, ArizonaAges 50 years+ - NCT05847985Recruiting
Noninvasive brain stimulation for thinking and language issues
This study tests whether a noninvasive brain stimulation treatment can improve sentence understanding in people with Parkinson’s disease–related mild cognitive impairment or mild cognitive impairment from Lewy body disease. It also compares results with healthy volunteers who do not have Lewy body or other memory/brain disorders.
BrnoAges 60–80 - NCT03664609Recruiting
Study of outcomes for people with deep brain stimulation
This study looks back at results for people who have already had deep brain stimulation (DBS) or could get it. It aims to understand how DBS is used and what outcomes people experience.
Phoenix, ArizonaAges Any age - NCT06041659Recruiting
Brain network changes during moyamoya bypass surgery
This study uses MRI scans to watch how brain networks work while you are asleep during moyamoya bypass surgery. It may help doctors understand how the brain adjusts after the procedure.
Beijing, Beijing MunicipalityAges 18–65 - NCT05070013Recruiting
Brain stimulation to improve sleep in people with Parkinson’s disease
This study tests an adaptive brain stimulation device to help restore better sleep in people with Parkinson’s disease. You may be eligible if your Parkinson’s motor symptoms are severe despite best medical treatment and you are already being considered for a specific deep brain stimulation surgery.
Omaha, NebraskaAges 18–80 - NCT06792877Recruiting
Mindfulness for thinking in early Alzheimer's
This study tests if mindfulness training can help protect thinking and memory in early-stage Alzheimer's disease. It compares mindfulness to other activities to see if it slows down memory loss.
Boston, MassachusettsAges 50–100 - NCT07835308RecruitingEarly Phase 1
Smart tuning of brain stimulation for better walking
This study is testing a new way to adjust deep brain stimulation (DBS) settings to improve walking in people with Parkinson's disease. If you have DBS and can walk with stimulation off, this trial may help fine-tune your treatment to improve your gait.
Minneapolis, MinnesotaAges 18 years+ - NCT07813559Recruiting
Using a special PET/CT scan to find blood clots
This study uses a special PET/CT scan to see blood clots in the body. The scan uses a tracer that sticks to a protein on blood clots, which might help doctors find clots that other scans miss.
Hefei, AnhuiAges 18–90 - NCT06197698Recruiting
Parkinson's and gut-brain connection study
This study is looking at how the bacteria in your gut might affect your brain in Parkinson's disease. It involves two types of brain scans to see differences between people with Parkinson's and healthy volunteers.
DouliuAges 20 years+ - NCT07476781Recruiting
Liquid biopsy study for solid tumours and brain tumours
This study collects samples of spinal fluid and blood from people with solid tumours that have spread to the brain or spine, or who have primary brain tumours. The goal is see if these samples can help doctors detect and monitor these cancers more easily.
Toronto, OntarioAges 18 years+ - NCT07374913Recruiting
Study of COL4A1 and COL4A2 gene mutations
This study looks at people with a mutation in the COL4A1 or COL4A2 genes, which can cause problems in small blood vessels throughout the body. It aims to learn more about the condition and may also include family members who carry the mutation or who can serve as healthy controls.
Florence, FIAges Any age - NCT06241482Recruiting
Enhanced recovery after brain surgery in intensive care
This study tests a special recovery program for people with serious brain injuries or strokes who need intensive care. The program focuses on helping you heal faster after surgery.
ShanghaiAges 18–75 - NCT07284784RecruitingPhase 2/Phase 3
Buntanetap for Parkinson's disease study
This trial tests an investigational drug called buntanetap in people with Parkinson's disease. It aims to see if the drug can improve symptoms. There are two groups: those who've taken buntanetap before (Cohort 1) and those with a deep brain stimulator (DBS) implant for at least a year (Cohort 2).
Birmingham, AlabamaAges 40–85 - NCT06953232Recruiting
Protein drink for heart and brain in midlife women
This study tests a special protein drink (whey with milk fat globule membrane) to see if it helps your heart and brain after a high-fat breakfast. It might help you if you are a postmenopausal woman at moderate risk for heart disease.
Loughborough, LeicestershireAges 50–75 - NCT06689410Recruiting
Brain aneurysm research registry and biobank
This study is collecting medical information and samples from people with brain aneurysms to learn more about the condition. If you have a recently found aneurysm, you may be able to help researchers understand how aneurysms form and how to better treat them in the future.
Nantes, Loire-AtlantiqueAges 18 years+ - NCT06352710Recruiting
Tracking recovery after brain or spine surgery
This study uses a smartphone app to track how you recover after brain or spine surgery. It helps doctors understand how side effects affect your daily life, so they can improve care.
Sankt Gallen, St.GallenAges 18 years+ - NCT06090201Recruiting
Brain health study for severe bleeding disorders
This study uses brain scans and thinking tests to understand how severe hemophilia or von Willebrand disease affects the brain and memory over time.
LilleAges 18 years+ - NCT02553525Enrolling by invitation
Testing different stimulation patterns in Parkinson’s, tremor, and MS
This study tests whether changing the “stimulation pattern” in a deep brain stimulator can improve how well symptoms are controlled. If you are already getting (or replacing) a deep brain stimulator, this may help fine-tune the settings for you.
Gainesville, FloridaAges 21–80 - NCT06618157Enrolling by invitation
Brain stimulation study for Parkinson's tremor
This study tests a new way to adjust deep brain stimulation (DBS) for Parkinson's disease. It focuses on people who still have at least mild tremor after their DBS device has been in place for three months or more, to see if targeting specific brain connections can help improve tremor control.
Durham, North CarolinaAges 18 years+ - NCT07682311Recruiting
Adjusting brain stimulation automatically for Parkinson's
This study tests a new way to adjust deep brain stimulation (DBS) automatically during the day to better control Parkinson's symptoms. It is for people who already have a Percept DBS device but still have motor fluctuations.
San Francisco, CaliforniaAges 25–75 - NCT06742450Recruiting
Comparing two ways to stimulate the brain for Parkinson's
This trial compares two methods of deep brain stimulation (constant current vs constant voltage) for people with Parkinson's who already have the device placed but haven't turned it on yet. The goal is to see which method works better.
BeijingAges 18–75 - NCT07573982Recruiting
Ultrasound brain treatment for early memory loss
This study tests a special ultrasound treatment that may help clear harmful brain waste linked to Alzheimer's. You would receive the treatment in six short sessions, and the researchers will check your memory and brain health to see if it helps.
Stanford, CaliforniaAges 18 years+ - NCT05662111RecruitingPhase 2
Etidronate treatment for brain calcifications in Fahr disease
This Phase 2 study tests whether etidronate (a medicine that affects bone-calcium handling) can help people with Fahr disease or a similar condition marked by calcium deposits in the brain. It will also check safety and whether certain tests can track changes over time.
Utrecht, UtrechtAges 18 years+ - NCT00575081Recruiting
Brain mapping during stereotactic procedures
This study builds a “brain atlas” by collecting information during stereotactic brain procedures. It may help doctors better plan and understand these brain procedures in the future.
Nashville, TennesseeAges 6–90
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Common questions
- Are there clinical trials for brain diseases?
- Yes. Clin2 currently lists 328 recruiting brain diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.