Clinical trials
Brain Tumor clinical trials
Below are recruiting brain tumor clinical trials, each written for real people, not researchers. We’re tracking 270 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04427384Recruiting
Brain tumor patients treated with GammaTiles registry
This study is a patient registry for people with brain tumors who had surgery to remove as much as safely possible and then had GammaTiles placed. It mainly collects information and follow-up imaging to understand how patients do after the treatment.
Phoenix, ArizonaAges Any age - NCT04075305Recruiting
Study measuring radiation treatment outcomes with an MR-Linac
This study follows what happens when radiation treatment is guided using an MR-Linac (a special machine that combines MRI imaging with radiation). It may help improve how radiation therapy is planned and assessed, especially for people who can safely have MRI scans.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT03684109Recruiting
MRI scans to study brain tumors using molecular imaging
This study uses special MRI scans to better “characterize” (study) gliomas, a type of brain tumor, using information from your brain tissue. You may be eligible if you’re an adult with a suspected or confirmed glioma and you already need a biopsy or surgery.
Miami, FloridaAges 18 years+ - NCT03213002RecruitingPhase 1/Phase 2
CAPTEM pills after brain radiation for newly diagnosed glioblastoma
This trial studies whether taking two chemotherapy pills (capecitabine and temozolomide) after the initial 6-week radiation-and-chemo phase can help people with newly diagnosed glioblastoma. It aims to test safety and early effectiveness right before the usual maintenance temozolomide phase.
New York, New YorkAges 18–74 - NCT02800486RecruitingPhase 2
Targeted antibody plus repeat radiation for recurrent brain tumors
This trial studies giving cetuximab (a targeted antibody) directly into an artery along with repeat radiation to treat certain recurring or treatment-resistant brain tumors. It may help by delivering the drug more directly to tumor areas and testing whether this approach can control the disease after it comes back.
New York, New YorkAges 18 years+ - NCT05672043Recruiting
Study genetic risks in children with malignant brain tumors
This study looks at genetic (DNA/molecular) features of malignant brain tumors in children. It may help doctors better understand tumor risk patterns and guide future treatment planning.
Beijing, Beijing MunicipalityAges birth–18 years - NCT06640582RecruitingPhase 1/Phase 2
TIL therapy with pembrolizumab for advanced brain cancer
This trial tests a new treatment for advanced brain cancers like glioma and meningioma. It combines your own immune cells (tumor-infiltrating lymphocytes or TILs) with an immunotherapy drug (pembrolizumab) to help your body fight the tumor. It's for people who have tried other treatments without success or have no standard options left.
Beijing, Beijing MunicipalityAges 16–90 - NCT07530536Recruiting
Brain Stimulation to Help Movement After Brain Tumor Surgery
This trial tests whether repetitive transcranial magnetic stimulation (rTMS)—a non-invasive treatment that uses magnetic pulses to stimulate the brain—can help restore arm or leg movement in patients who have had weakness after brain tumor surgery. The goal is to see if this treatment is safe and effective for people recovering from surgery.
New York, New YorkAges 22–65 - NCT07413796Recruiting
Comparing skin closure methods in brain tumor surgery
This study compares two ways to close the skin after brain tumor surgery: a continuous stitch under the skin versus separate stitches through the skin. The goal is to see which method leads to better healing and appearance.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07338526Recruiting
Proton therapy for children with brain tumors
This trial tests if a precise type of radiation called proton therapy is safe and effective for children with certain brain tumors. It aims to reduce side effects by focusing radiation only on the tumor.
Mumbai, MaharashtraAges 6–16 - NCT07323966Recruiting
Mask-free radiation for brain tumor patients
This study tests whether brain tumor patients can safely receive radiation therapy without wearing a face mask. The goal is to see if it is a more comfortable and feasible option.
Woluwe-Saint-Lambert, Brussels CapitalAges 18 years+ - NCT06282562Recruiting
High-intensity interval training for brain tumor patients
This study tests whether a high-intensity interval training program can help brain tumor patients feel fitter and more energetic. It's for people with stable tumors who aren't currently on treatment.
AmsterdamAges 18 years+ - NCT06943742Recruiting
Brain scan without helium for children with brain tumors
This study uses a special type of brain scan (magnetoencephalography, or MEG) that doesn't need helium gas to see brain activity in children with brain tumors. The goal is to see if this scan can help doctors plan surgery or treatment better.
Guangzhou, GuangdongAges 3–18 - NCT07003139RecruitingPhase 1/Phase 2
BNCT for High-Grade Malignant Brain Tumors
This trial tests a special type of radiation therapy called boron neutron capture therapy (BNCT) for people with high-grade malignant brain tumors. It aims to see if BNCT is safe and effective for tumors that have not been treated or have come back after standard treatments.
HsinchuAges 18 years+ - NCT06831461Recruiting
Proton vs photon radiation for brain tumors
This study compares two types of radiation therapy for adults with primary brain tumors that have a good outlook (expected survival longer than 5 years). You will receive either standard photon radiation or the more targeted proton radiation, to see if one works better or causes fewer side effects.
MumbaiAges 18–70 - NCT06804655RecruitingPhase 2
Personalized drug testing for stubborn brain tumors
This study tests a new way to choose treatment for people with brain tumors that have not responded to standard therapies. Your tumor sample is analyzed in the lab to find which drugs might work best for you, and then you receive a personalized treatment plan.
Basel, Basel-LandschaftAges 18 years+ - NCT06442748RecruitingPhase 3
Short vs long seizure medicine in brain tumor patients
This study compares stopping seizure medicine (levetiracetam) after 6 months versus continuing it longer for people with primary brain tumors. It aims to find out if it is safe to stop the medication sooner and may help you avoid long-term side effects.
Udupi, KarnatakaAges 18 years+ - NCT05340881Recruiting
Light exposure program for young survivors of childhood brain tumors
This trial studies whether a structured light-exposure routine can improve symptoms like fatigue and how survivors feel day to day. It is aimed at children and teens who have recovered from a non–high-risk type of brain tumor and have mild to moderate fatigue.
Houston, TexasAges 10–18 - NCT05629702RecruitingPhase 2
Temozolomide with or without cannabinoids for recurrent brain tumor
This trial tests whether adding cannabinoid medicine to temozolomide helps people whose glioblastoma (GBM) has returned. It compares temozolomide plus cannabinoids versus temozolomide alone, using blinded treatment so neither you nor the team knows which option you get.
Bodelwyddan, DenbighshireAges 16 years+ - NCT05298995RecruitingPhase 1
GD2 CAR T-cell treatment for pediatric brain tumors
This trial tests a special immune-cell therapy (GD2 CAR T cells) made for pediatric brain tumor patients. It uses a planned treatment plan and monitoring to see if the therapy is safe and can work against the tumor.
Roma, ItalyAges 6 months–30 years - NCT05293197RecruitingPhase 1
Safety study of repeated blood-brain barrier opening for pediatric brain tumors
This Phase 1 study tests whether a device can safely and repeatedly open the blood-brain barrier (a protective shield in the brain) in children with malignant brain tumors. It aims to help the tumor treatment work better while watching for safety issues.
ParisAges 5–17 - NCT00811148Recruiting
Study for people having brain tumor surgery
This study is for people (children or adults) who are planning brain surgery to remove tumor tissue. It may help researchers learn about care for brain tumors and how outcomes can be improved.
Gainesville, FloridaAges Any age - NCT05521984RecruitingPhase 1
Dapagliflozin trial for children with hard-to-treat brain tumors
This Phase 1 trial tests whether dapagliflozin (an SGLT2 medicine) can help shrink or control certain pediatric brain tumors or other solid tumors that have come back or won’t respond. It’s designed mainly to check safety and early signs of effect in children and young adults who have limited treatment options.
St Louis, MissouriAges 6–21 - NCT03911388RecruitingPhase 1
HSV G207 for Children with Recurrent Cerebellar Brain Tumors
This trial is testing a virus called HSV G207, which is injected directly into the tumor, to treat children and young adults with a type of brain tumor in the cerebellum that has come back or not responded to standard treatments.
Birmingham, AlabamaAges 3–22
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Common questions
- Are there clinical trials for brain tumor?
- Yes. Clin2 currently lists 270 recruiting brain tumor studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain tumor trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain tumor trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.