Clinical trials
Brain Tumor clinical trials
Below are recruiting brain tumor clinical trials, each written for real people, not researchers. We’re tracking 269 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03861299Recruiting
Awake brain surgery versus sleep surgery for glioblastoma
This study compares two ways of doing brain surgery for glioblastoma: doing parts of the operation while you are awake, versus doing it fully under general anesthesia (sleep). It aims to see which approach is safer and better for protecting brain functions like speech and movement while removing the tumor.
GhentAges 18–90 - NCT07810673Recruiting
Physical function and quality of life in children with brain tumors
This study looks at how physical abilities and quality of life are affected in children with brain tumors. It involves physical testing and questionnaires, and aims to understand the impact of the tumor and its treatment.
CairoAges 7–10 - NCT05976490Recruiting
Support program for people newly diagnosed with brain cancer
This study tests a “NeuroPathways” support intervention for adults who are within 6 weeks of being diagnosed with a malignant (cancerous) brain tumor. It may help patients cope and navigate care during the early, stressful period after diagnosis.
Boston, MassachusettsAges 18 years+ - NCT02914067Recruiting
Testing brain scan and computer measures in young brain tumor patients
This study looks at “brain biomarkers,” meaning brain signals measured on MRI and thinking/learning tests on a computer. It may help researchers understand how brain tumors affect the brain and track changes over time.
St Louis, MissouriAges 4–18 - NCT04692337Recruiting
Ommaya device for easier testing of brain tumor fluid
This study places a small device in the brain area (called an Ommaya reservoir) so doctors can collect brain fluid to test tumor markers over time. It may help researchers learn more about brain tumors, while also fitting alongside your planned brain surgery at Mayo Clinic.
Rochester, MinnesotaAges 18 years+ - NCT02861898RecruitingPhase 1/Phase 2
Cetuximab delivered into the brain tumor artery for new glioblastoma
This Phase 1/2 study tests whether giving cetuximab directly into the artery that feeds the brain tumor can help people with newly diagnosed glioblastoma. It aims to target the tumor more precisely while checking safety and early signs of benefit.
New York, New YorkAges 18 years+ - NCT06136884RecruitingPhase 1
Study of AO-252 for advanced solid tumors with or without brain metastases
This trial tests an experimental oral pill (AO-252) that targets a protein called TACC3 in advanced solid tumors, including those that have spread to the brain. It is for people whose cancer has a specific genetic change (TP53 mutation) or who have prostate cancer, and who have already tried other treatments.
Detroit, MichiganAges 18 years+ - NCT07132190RecruitingPhase 2
Radiation for growing brain tumors with same-day planning
This study tests whether a precise, one-day radiation treatment for brain tumors that are growing or in tricky spots can be effective with a smaller safety margin. It's designed for people whose brain tumors are changing quickly or sitting near areas of swelling or recent surgery.
Boston, MassachusettsAges 18 years+ - NCT05254197Recruiting
Brain tumor monitoring study with follow-up brain scans
This study follows people with lower-grade (WHO grade 2 or less) brain tumors using repeat MRI scans over time. It helps doctors understand how these tumors change and which patients may safely delay treatment at first.
SeoulAges 18 years+ - NCT02824731Recruiting
Proton vs photon radiation for certain brain tumors
This study compares two types of radiation—protons and photons (X-rays)—for specific brain tumors or tumor returns. It aims to see which approach works best and is safest for you, based on how much and where the radiation is delivered.
DresdenAges 18 years+ - NCT06381531Recruiting
Tracing brain tumors through imaging over time
This study looks at CT or MRI scans of people with primary brain tumors to understand how these tumors change over time. It may help you if you have imaging before and after surgery or before radiation.
Mumbai, MaharashtraAges Any age - NCT05474573Recruiting
Laser-guided removal of brain tumors using special light
This study tests a method to help surgeons find and remove brain tumors that show up on MRI with contrast dye (often high-grade gliomas and brain metastases). If you newly have one of these tumors, the trial may help improve how completely tumors can be removed while protecting important brain areas.
MoscowAges 18–79 - NCT06962215Recruiting
Simulation training for paramedics caring for brain tumor patients
This study tests whether training paramedics with realistic simulations can improve the hospital experience for patients with malignant brain tumors. If you are staying in neurosurgery before your diagnosis is confirmed, you may be able to join.
Brest, Brittany RegionAges 18 years+ - NCT06878469Recruiting
Simplifying care for rare brain tumors with AI
This study uses artificial intelligence to improve care for adults with rare brain tumors who are scheduled for surgery. It aims to make treatment pathways simpler and better tailored to each patient.
Milan, PAAges 18 years+ - NCT06099743Recruiting
Support program for people with brain tumors
This study tests a support program that helps people with brain tumors cope with their diagnosis and treatment. The program uses acceptance and commitment therapy, which focuses on accepting difficult emotions and committing to actions that improve well-being.
Boston, MassachusettsAges 18 years+ - NCT07417072Recruiting
Brain tumor drug testing using 3D models in children
This study creates 3D models from brain tumor tissue of children aged 3-18 to test how different drugs might work against their specific tumor. The goal is to find more personalized treatments.
Florence, FirenzeAges 3–18 - NCT07239115RecruitingPhase 3
Levetiracetam to prevent seizures after brain tumor surgery
This trial tests whether the drug levetiracetam can prevent seizures in people who have brain tumor surgery. If you are having surgery to remove a brain tumor and have never had a seizure, this study may help keep you from having one after the operation.
BeijingAges 18–75 - NCT06501521Recruiting
Non-invasive brain tumor testing and monitoring
This study is testing a new, non-invasive way to diagnose and monitor brain tumors. It may offer a less risky option compared to traditional biopsies.
OlomoucAges 18–99 - NCT05064280RecruitingPhase 2
Pembrolizumab plus lenvatinib for brain metastases from solid tumors
This Phase 2 trial studies whether combining pembrolizumab with lenvatinib can shrink or control brain metastases in people with triple-negative breast cancer, lung cancer, or other solid tumors. It focuses on patients who have measurable brain lesions that can be followed on MRI.
Houston, TexasAges 18 years+ - NCT03286335Recruiting
Proton radiation for slow-growing or benign brain tumors
This trial studies proton radiation therapy for adults with certain benign or slow-growing brain tumors. It aims to see how well tumors can be controlled, and how treatment affects quality of life and side effects.
Boston, MassachusettsAges 18 years+ - NCT06193759RecruitingPhase 1
Immune cell therapy for malignant pediatric brain tumors
This trial tests a new immune therapy using your child's own specially trained white blood cells to fight brain tumors. The treatment is given directly into the fluid around the brain, and it is for children with specific types of brain cancer.
Washington D.C., District of ColumbiaAges 1–30 - NCT01668082Recruiting
Study brain tumor metabolism during planned brain surgery
This study looks at how brain tumors use energy (“metabolism”) during planned surgical removal. It may help researchers learn what makes tumors grow and how to improve future brain tumor treatments.
Dallas, TexasAges 18 years+ - NCT05397873Recruiting
Biofeedback training to improve vision in hemianopia
This trial tests whether guided “biofeedback” training can help people with hemianopia (a vision field loss) improve how they use their remaining vision. You may be asked to complete vision testing and practice exercises while receiving feedback based on your responses.
Toronto, OntarioAges 18–90 - NCT07158710RecruitingPhase 1
Study of HSK42360 for brain tumors with BRAF V600 mutation in children
This trial tests a new drug, HSK42360, for children with recurrent brain tumors that have a specific gene change called BRAF V600. The goal is to see if the drug can help when standard treatments have stopped working.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for brain tumor?
- Yes. Clin2 currently lists 269 recruiting brain tumor studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain tumor trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain tumor trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.