Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,015 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06688162Enrolling by invitation
Minimally invasive surgery for small brain bleeds
This trial tests a less invasive surgery to remove small blood clots (20–30 ml) in the basal ganglia, a deep part of the brain. It may help people who are awake but have a reduced level of consciousness after a recent brain bleed.
BeijingAges 18–80 - NCT06667726RecruitingPhase 2
New PET scan for better brain tumor care
This trial studies a special PET scan called 18F-DOPA PET/CT to see if it can help doctors better manage brain tumors. It may be used before surgery, for radiation planning, or when MRI results are unclear.
Rochester, MinnesotaAges 18 years+ - NCT06018363RecruitingPhase 1/Phase 2
Cell therapy for recurrent high-grade glioma
This trial tests a new cell therapy (QH104) for people with an aggressive brain tumor called high-grade glioma that has come back or worsened after standard treatment. The therapy targets a specific protein (B7-H3) on tumor cells to try to fight the cancer.
Suzhou, JiangsuAges 18–70 - NCT06642519Enrolling by invitation
Brain-computer interface for freezing of gait in Parkinson's
This study tests a brain-computer interface device to help people with Parkinson's disease who experience freezing of gait. The goal is to see if the device can reduce freezing episodes when medication isn't enough.
Toronto, OntarioAges Any age - NCT06503484Recruiting
Brain training with light for stroke arm recovery
This trial tests whether a brain-computer interface (BCI) using near-infrared light can help stroke survivors improve hand and arm movement. You'll receive a type of brain training called neurofeedback during the study.
Hong Kong, Hong KongAges 18–75 - NCT06607523Recruiting
Prebiotic treatment for brain injury recovery
This study tests whether a prebiotic (a type of fiber that feeds healthy gut bacteria) can improve recovery from a brain injury by helping the connection between the gut and the brain. Participants include people with a recent brain injury and their family members or staff, all of whom are part of the Moody Neurorehabilitation Institute community.
Galveston, TexasAges 18 years+ - NCT06617208Recruiting
Brain wave monitoring during brain tumor surgery
This study tests a new way to monitor brain activity during surgery to remove brain tumors. It may help doctors better protect important brain functions during the operation.
Rotterdam, South HollandAges 18 years+ - NCT06604000Recruiting
Goal management training for cognitive control after brain injury
This trial tests a training program called Goal Management Training (GMT) to help people who have had a brain injury improve their ability to plan, focus, and stay organized. If you have trouble with these skills and your injury happened at least a year ago, this training might help you get better at everyday tasks.
TrondheimAges 18–65 - NCT06611306Recruiting
Targeted whole-brain radiation for breast cancer that spread to the brain
This trial tests a newer, more targeted way to give whole-brain radiation for breast cancer that has spread to the brain. It aims to see if this approach can be as effective while causing fewer side effects compared to the standard whole-brain radiation.
London, LondonAges 16–100 - NCT06617377Recruiting
Can MRI predict brain recovery after cardiac arrest?
This study uses brain scans (MRI) to try to predict whether people who are still unconscious after a cardiac arrest will recover. It is looking for adults who are in a coma and have not woken up after being taken off sedation medicines for at least three days.
ToulouseAges 18 years+ - NCT06585618Recruiting
Pediatric Deep Brain Stimulation Registry
This study creates a list of children who already have or plan to get Deep Brain Stimulation (DBS) to see how it helps with movement problems. Joining helps doctors learn more about how DBS works in kids.
Boston, MassachusettsAges birth–18 years - NCT06595914Enrolling by invitation
Improving education for mild traumatic brain injury
This trial is working to improve how doctors and nurses teach patients about mild traumatic brain injury (mTBI) in the emergency room and after they go home. It may help you get clearer information and support during recovery.
Milwaukee, WisconsinAges 18 years+ - NCT06581003RecruitingPhase 3
Hyperbaric oxygen for veterans with lasting brain injury symptoms
This trial tests whether breathing pure oxygen inside a pressurized chamber (hyperbaric oxygen therapy) can help reduce long-term symptoms after a mild or moderate traumatic brain injury. It is for veterans and service members who have had a TBI at least one year ago and are still struggling with symptoms.
Tampa, FloridaAges 18–75 - NCT06573658Recruiting
Brain changes after balance training in older adults
This study looks at how the brain changes after balance exercises that challenge your stability. It may help find better ways to prevent falls in older adults.
Hong KongAges 60 years+ - NCT06582940RecruitingPhase 2
MRI-guided radiation for lung cancer with brain metastases
This trial tests a new way to deliver radiation to brain metastases from non-small cell lung cancer, using MRI scans to guide the treatment and reduce the area exposed. The goal is to see if this approach is safe and effective while possibly lowering side effects.
Guangzhou, GuangdongAges 18–75 - NCT06058351Recruiting
Brain injury aftercare at home
This trial tests a home-based aftercare program for people with acquired brain injury (ABI). It aims to improve recovery by offering multidisciplinary support in your own home.
RotterdamAges 18 years+ - NCT06551987Recruiting
Insomnia treatment for military members with mild brain injury
This study tests a behavioral insomnia therapy for active-duty service members who have had a mild traumatic brain injury and continue to have sleep problems and other symptoms. It aims to help improve sleep and recovery.
Fort Cavazos, TexasAges 18–45 - NCT06533176Recruiting
Personalized brain stimulation after stroke
This study tests a new way to apply brain stimulation called TMS while watching your brain activity in real time, tailored to your personal brain state. It is for people who still have arm or hand weakness at least 6 months after a stroke.
Iowa City, IowaAges 18 years+ - NCT06544408Recruiting
Brain stimulation for fast relief of PTSD
This study tests a rapid, non-invasive brain stimulation treatment to reduce PTSD symptoms. It aims to offer a faster way to help adults with PTSD feel better.
Tallahassee, FloridaAges 18–65 - NCT05716048RecruitingPhase 1
Rehab program study for adults with lasting brain injury symptoms
This Phase 1 trial tests a combined rehabilitation program to improve function in people living with moderate-to-severe traumatic brain injury (TBI) for at least a year. It may help people who still have new problems with learning and memory and who are not very physically active.
West Orange, New JerseyAges 18–65 - NCT06496971RecruitingPhase 3
Testing focused ultrasound plus Avastin for recurrent glioblastoma
This study tests whether adding focused ultrasound to the standard drug Avastin (bevacizumab) can help treat recurrent glioblastoma. The ultrasound may help more of the drug reach the tumor.
TaipeiAges 18–80 - NCT06504238Recruiting
Non-invasive monitoring for acute brain injury
This trial tests special cameras and sensors that check your brain without surgery. It may help doctors watch for brain swelling and other problems more safely.
Boston, MassachusettsAges 18 years+ - NCT05236946RecruitingPhase 3
Brain radiation timing study for gene-mutated lung cancer
This study compares giving brain radiation right away versus waiting, in people with lung cancer that has an EGFR or ALK gene change and has spread to the brain but causes no symptoms. It aims to see which approach helps control the brain cancer better and keeps quality of life stable.
Mumbai, MaharashtraAges 18–99 - NCT06469801Recruiting
Checking for brain injury in children on ecmo with a portable mri
This study uses a small, portable MRI machine to look for brain injury in children on ECMO (a life-support machine for the heart and lungs). The hope is to spot problems early so they can be treated sooner.
Kansas City, MissouriAges birth–17 years
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,015 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.