Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,015 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06469801Recruiting
Checking for brain injury in children on ecmo with a portable mri
This study uses a small, portable MRI machine to look for brain injury in children on ECMO (a life-support machine for the heart and lungs). The hope is to spot problems early so they can be treated sooner.
Kansas City, MissouriAges birth–17 years - NCT06469983Recruiting
Robotic vs. traditional standing therapy for severe brain injury
This trial compares using a robotic device versus standard therapy to help people with severe brain injury practice standing. It tests whether the robotic approach leads to better recovery of standing ability.
Sant'Angelo dei Lombardi, AvellinoAges 18–75 - NCT06442748RecruitingPhase 3
Short vs long seizure medicine in brain tumor patients
This study compares stopping seizure medicine (levetiracetam) after 6 months versus continuing it longer for people with primary brain tumors. It aims to find out if it is safe to stop the medication sooner and may help you avoid long-term side effects.
Udupi, KarnatakaAges 18 years+ - NCT06449989Recruiting
Comparing genetics of colorectal cancer and its brain spread
This study compares the genetics of the original colorectal cancer with the cancer that has spread to the brain. It aims to understand how the tumor changes when it metastasizes, which may help guide future treatments.
Moscow, MoscowAges 18 years+ - NCT06431685RecruitingPhase 1
Brain radiation, immunotherapy, and chemo for lung cancer spread
This trial tests a combination of low-dose radiation to the whole brain, immunotherapy, and chemotherapy given through a lumbar puncture. It is for people with lung cancer that has spread to the lining of the brain and has not responded to standard treatments.
Chengdu, SichuanAges 18–75 - NCT05340881Recruiting
Light exposure program for young survivors of childhood brain tumors
This trial studies whether a structured light-exposure routine can improve symptoms like fatigue and how survivors feel day to day. It is aimed at children and teens who have recovered from a non–high-risk type of brain tumor and have mild to moderate fatigue.
Houston, TexasAges 10–18 - NCT05327387Recruiting
Brain stimulation study using implanted electrodes
This study tests a model-based way of using electrical brain stimulation in people who are having surgery for drug-resistant epilepsy or brain tumors. It uses implanted electrodes to measure brain activity and may help improve how stimulation is planned during surgical care.
Los Angeles, CaliforniaAges 18 years+ - NCT06319027RecruitingPhase 2
Can brain scans help predict glioblastoma progression?
This trial is testing whether certain details on brain scans can help doctors better predict how brain cancer (glioblastoma) will progress. You may be eligible if you are newly diagnosed with this type of cancer and plan to receive standard treatment.
Birmingham, AlabamaAges 18 years+ - NCT06322602Recruiting
Brain tumor biopsy with Ommaya reservoir for fluid collection
This study places a small reservoir under your scalp during a brain tumor biopsy to collect fluid samples over time. It may help doctors learn more about your tumor and how it responds to treatment.
Rochester, MinnesotaAges 18 years+ - NCT04080440Recruiting
Checking readiness to remove the breathing tube after brain injury
This study looks at how to judge when it is safe to remove the breathing tube in people in the ICU after a brain injury. It may help improve timing and safety of extubation, when supported by a breathing trial and clinical stability.
AngersAges 18–75 - NCT06298474Recruiting
BRAIN App for dementia support
This study is testing a new app (BRAIN App) designed to help people with dementia stay connected and engaged. Researchers want to see if the app can be useful for older adults who can still communicate and have not had a recent fast decline in health.
Winchester, MassachusettsAges 65 years+ - NCT06303921RecruitingEarly Phase 1
Study of a new brain imaging agent for Parkinson's disease
This trial uses a special PET scan to see how a new imaging agent (called 11C-M503) travels through the body and brain. It may help researchers better understand brain conditions like Parkinson's disease.
New Haven, ConnecticutAges 40–85 - NCT06315010RecruitingPhase 2
Repotrectinib for lung cancer with brain metastasis
This trial tests a targeted pill called repotrectinib for people with a specific type of lung cancer (ROS1-positive non-small cell lung cancer) that has spread to the brain. The drug aims to shrink brain tumors and control the cancer, especially when brain-focused treatments like surgery or radiation are not needed right away.
GrazAges 18 years+ - NCT06293638Recruiting
Brain changes during deep brain stimulation for essential tremor
This study looks at how deep brain stimulation (DBS) affects brain networks in people with essential tremor (ET). The goal is to understand the brain changes that happen during DBS treatment, which may help improve the therapy.
Cleveland, OhioAges 30–80 - NCT06282965RecruitingPhase 1/Phase 2
Angiotensin (1-7) for moderate to severe brain injury
This study tests a drug called Angiotensin (1-7) to see if it helps people recover from moderate to severe traumatic brain injury. It may reduce damage and improve healing when given shortly after the injury.
Tucson, ArizonaAges 18 years+ - NCT06279975Recruiting
Pupil test in patients being checked for brain death
This study uses a special camera to measure pupil reactions in patients being evaluated for brain death. The aim is to see if this test can help confirm the diagnosis of brain death more accurately.
Basel, Canton of Basel-CityAges 18 years+ - NCT06293300RecruitingPhase 2
Botulinum toxin for light sensitivity after brain injury
This study tests if botulinum toxin type A (Botox) can reduce long-term light sensitivity in people who have had a traumatic brain injury at least a year ago. You must have had light sensitivity for 6 months or more and not have had Botox for face or mouth conditions before.
Miami, FloridaAges 18 years+ - NCT06280300Recruiting
Better care planning for people with brain metastases
This study looks at whether a team-based approach to care can improve quality of life for people newly diagnosed with brain metastases from solid tumors. It aims to help coordinate your medical and support needs.
Burlington, VermontAges 18 years+ - NCT06263660RecruitingPhase 2
Keto supplement for depression with inflammation
This study tests a keto-like supplement to see if it helps change how the brain responds to emotional situations in people with depression and higher inflammation. It involves MRI brain scans and blood tests.
Tulsa, OklahomaAges 18–65 - NCT06257056Recruiting
Deep brain stimulation for hard-to-treat schizophrenia
This trial tests whether deep brain stimulation (a device that sends electrical pulses to specific areas of the brain) can help people with schizophrenia whose symptoms have not improved with standard treatments. If you have ongoing psychosis and have tried several medications without success, this study may be an option for you.
Dallas, TexasAges 22–70 - NCT06253871RecruitingPhase 1
Study of IAM1363 for HER2 Cancers
This trial tests a new oral drug called IAM1363 for people with HER2-altered cancers that have stopped responding to previous treatments. The goal is to see if the drug is safe and how well it works against these cancers.
La Jolla, CaliforniaAges 18 years+ - NCT06247449Recruiting
MRI screening for brain metastases in aggressive breast cancer
This trial uses an MRI scan to look for early signs of breast cancer spreading to the brain in people with certain aggressive breast cancer types (triple-negative or HER2-positive) that are stage IIb or III. The goal is to find and treat brain metastases earlier, before they cause symptoms.
Toronto, OntarioAges 18 years+ - NCT06244472Recruiting
New brain scanner for fast brain imaging
This study uses a new type of brain scanner (MEG) to take very fast pictures of brain activity. It's for healthy people or those who've had a mild concussion recently.
BronAges 18–70 - NCT06193759RecruitingPhase 1
Immune cell therapy for malignant pediatric brain tumors
This trial tests a new immune therapy using your child's own specially trained white blood cells to fight brain tumors. The treatment is given directly into the fluid around the brain, and it is for children with specific types of brain cancer.
Washington D.C., District of ColumbiaAges 1–30
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,015 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.