Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06324786Recruiting
Brain training to reduce alcohol, cannabis, and tobacco use
This study tests whether a type of brain training called neurofeedback can help people reduce their use of alcohol, cannabis, and cigarettes. If you're an adult who uses all three heavily and have no other mental health conditions, you may be eligible.
Phoenix, ArizonaAges 18 years+ - NCT05417542Recruiting
Study how young brains hear rhythms
This study looks at how babies’ brains process rhythm and sound. It may help researchers understand early brain development, especially from premature birth through infancy.
AmiensAges birth–18 years - NCT06902298RecruitingPhase 1/Phase 2
Ultrasound brain stimulation for depression
This trial tests a new, non-invasive ultrasound treatment for people with depression who haven't gotten enough relief from at least two prior treatments. It uses sound waves to gently stimulate areas of the brain linked to mood.
Salt Lake City, UtahAges 18–65 - NCT06881147Enrolling by invitation
Physiotherapy and Botox for Neck Dystonia
This study tests whether combining physiotherapy with Botox injections can improve neck control in people with cervical dystonia. It also looks at how 'sensory tricks' (like touching your face) help the brain control symptoms, using brain scans to understand why.
Milan, ItaliaAges Any age - NCT06779188RecruitingEarly Phase 1
Brain stimulation to improve balance in older adults
This trial tests whether a non-invasive brain stimulation technique called theta burst TMS can improve balance and brain connectivity in adults over 65 who have had recent falls. It involves MRI scans, 4 weeks of treatment, and follow-up tests.
Houston, TexasAges 65 years+ - NCT06945705RecruitingPhase 2
Targeted therapy for EGFR-mutant lung cancer with brain spread
This trial tests a combination of two targeted pills (furmonertinib and anlotinib) as a first treatment for people with advanced EGFR-mutant non-small cell lung cancer that has spread to the brain. It aims to see if this combination works better than the standard approach for controlling the cancer.
ZhengzhouAges 18 years+ - NCT06771531Recruiting
Brain stimulation for foot sensation in older adults
This trial tests whether a gentle brain stimulation technique can improve feeling and steadiness in the feet of older adults who have numbness or reduced sensation. It aims to help with balance and walking.
Roslindale, MassachusettsAges 65 years+ - NCT07249801Recruiting
Brain stimulation study for hand grip and vision coordination
This trial uses a technique called closed-loop rTMS-EEG, which combines brain stimulation with brain-wave monitoring, to study how the brain controls hand grip based on visual cues. It may help researchers understand movement and vision integration.
Charleston, South CarolinaAges 18 years+ - NCT06243016Recruiting
Breaking sitting with high-intensity exercise for brain health
This study tests whether breaking up long periods of sitting with short bursts of high-intensity exercise can improve brain health. It is for people who are sedentary and not very active but otherwise generally healthy.
Urbana, IllinoisAges 40–75 - NCT07220265Recruiting
PKU carriers: How high phenylalanine affects the brain
This study looks at how carrying one copy of the PKU gene might affect thinking and brain health in adults. It will help researchers understand if mild changes in a substance called phenylalanine can impact memory, focus, and brain scans.
Columbia, MissouriAges 18–60 - NCT05265546RecruitingPhase 1
Psilocybin study of changes in how you see
This Phase 1 study tests whether psilocybin affects visual perception and how visual information is represented in the brain. It also studies safety and what brain/vision changes happen after the dose.
Berkeley, CaliforniaAges 21 years+ - NCT06379971RecruitingPhase 1
Choline for cannabis use in pregnancy
This trial tests whether taking choline (a vitamin-like nutrient) during pregnancy can help protect the baby's brain development in women who use cannabis. It aims to understand if choline supplementation can reduce potential risks linked to cannabis use.
Aurora, ColoradoAges 18–45 - NCT06922500Recruiting
Brain-Wave Monitoring During Brain Tumor Surgery
This study tests a special brain-wave monitor (called processed EEG) during surgery to remove a brain tumor. The monitor helps the anesthesiologist keep you at the right level of sleep, which may improve safety and recovery.
LundAges 18 years+ - NCT07063732Recruiting
Ketone drink, high altitude, and brain blood flow during exercise
This trial tests whether a ketone monoester supplement affects brain blood flow and exercise performance at high altitude. It may help us understand how to support brain function during altitude exposure.
Bishop, CaliforniaAges 18–35 - NCT05449106Recruiting
Medical-only care study for unruptured brain AVMs
This study looks at outcomes for people with an unruptured brain arteriovenous malformation (AVM) using medical care only, without procedures. It may help doctors understand which medical approach and monitoring works best for different AVM locations seen on CT scans.
Beijing, Beijing MunicipalityAges 3–80 - NCT07115394Recruiting
Brain wave tracking during DBS for movement disorders
This study uses EEG (a non-invasive scalp recording) to measure brain signals while deep brain stimulation (DBS) is active. It aims to better understand how DBS affects brain activity in people with Parkinson's disease, essential tremor, or dystonia.
HamburgAges 35–85 - NCT06629090RecruitingPhase 2
Brain blood vessel responses to blood flow changes: younger adults
This study looks at how the brain's blood vessels respond to changes in blood flow in healthy younger adults. It helps researchers understand normal brain aging.
Madison, WisconsinAges 20–40 - NCT07127224Recruiting
Predicting recovery with smell tests in coma
This study tests whether a simple smell test can help predict recovery of consciousness in patients who remain in a coma or minimally conscious state after a severe brain injury. If you or your loved one has been unresponsive for several days after sedation is stopped, this trial may provide useful information about prognosis.
Paris, GHU Psychiatrie Et NeurosciencesAges 18 years+ - NCT05909618RecruitingPhase 2
Crizanlizumab with nivolumab for brain-spread melanoma or glioblastoma
This Phase 2 study tests crizanlizumab alone or with nivolumab to treat people with certain brain tumors that have spread to the brain (melanoma) or glioblastoma. The goal is to see whether this approach can control the disease and improve outcomes.
Ramat Gan, IsraelAges 18 years+ - NCT07075523Recruiting
Brain scans and markers after CAR T-cell therapy
This study uses brain scans and blood markers to understand how CAR T-cell therapy affects the brain. It may help researchers predict or manage potential side effects.
La Jolla, CaliforniaAges 18 years+ - NCT04290130Enrolling by invitation
Study brain signals during audiovisual speech in neurosurgery patients
This study measures brain activity to understand how your brain combines what you see and hear during speech. It may help scientists build better ways to understand and treat problems with speech processing.
Philadelphia, PennsylvaniaAges 21–65 - NCT06721468Recruiting
Trout eating and brain health in kids and families
This study looks at how eating trout may affect brain health in children and their families. It has three parts for different age groups, and you may be asked to eat trout or answer questions online.
Moscow, IdahoAges 3 years+ - NCT06971549Recruiting
Faster TMS for depression with brain monitoring
This study tests a faster version of TMS (called iTBS) to treat depression, while using a special headband to monitor brain blood flow in real time. It's for people whose depression hasn't gotten better with at least one antidepressant medication.
Hong KongAges 18–65 - NCT05913297Recruiting
Checking how Chiari malformation affects airways and sleep in children
This study looks at how Chiari malformation (types 1 and 2) may affect a child’s breathing/airways, the base of the skull, and sleep. The results may help doctors better understand which problems to watch for and how to evaluate them.
Rome, ItalyAges 3–18
Hear when a new Brain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.