Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,015 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06329726Recruiting
Thinking and memory after brain stimulation for Parkinson's
This study looks at how deep brain stimulation (DBS) affects thinking and memory in people with Parkinson's disease over time. It compares results from people who have DBS and those who receive only medication.
Milan, LombardyAges 18–70 - NCT06335836Recruiting
Social connections and brain health in memory decline
This study looks at how being socially isolated or socially active affects memory and brain health in people who feel their thinking is getting worse. You may join if you notice a slow decline in memory or thinking, but otherwise have normal test results.
Nanjing, China, JiangsuAges 45–85 - NCT06231186Recruiting
Study of iHD-SRT for brain metastases
This study tests a new type of radiation therapy (iHD-SRT) for people with brain metastases. It aims to see if this approach is safe and effective for treating tumors that have spread to the brain.
Shanghai, Shanghai MunicipalityAges Any age - NCT05539677Recruiting
Research biobank and patient registry for aggressive solid tumors
This study builds a biobank and patient registry using tumor samples and blood. It helps researchers better understand aggressive cancers and may improve future treatments by testing immune (defense) responses.
Saint PetersburgAges 1 year+ - NCT05296980Recruiting
Testing a dementia risk-reduction program for older adults
This study checks whether a program called REMINDER can help reduce risk of developing dementia by improving risk factors over 12 weeks. It’s for older adults who have higher dementia risk but do not currently have dementia.
CoimbraAges 60–75 - NCT05727605Recruiting
Thinking changes after radiotherapy for brain and skull-base tumors
This trial studies how radiotherapy affects memory and thinking in adults with certain brain or skull-base tumors. It may help doctors understand who is most likely to have thinking changes and how to monitor or support patients.
GhentAges 18 years+ - NCT06048796Recruiting
Early stopping of sedation after cardiac arrest with normal EEG
This study is testing whether it is safe to stop sedation and temperature management early in cardiac arrest patients who have a normal-looking brain wave test (EEG). If you qualify, you would stop sedation sooner than usual, which may help you wake up faster.
Arnhem, GelderlandAges 18 years+ - NCT03418441Recruiting
Study infections of the brain and spinal fluid in Denmark
This trial focuses on people in Denmark who may have an infection in the brain or the fluid around the brain and spinal cord. Researchers aim to collect and compare diagnostic results for different infection types (viral meningitis, bacterial meningitis, encephalitis, and others) to help confirm the cause and guide care.
AalborgAges 18 years+ - NCT06418113RecruitingPhase 1
Radiation and chemo before surgery for glioblastoma
This trial tests giving radiation and chemotherapy before surgery for glioblastoma. It aims to see if this approach is safe and may help improve outcomes for patients whose tumor can be completely removed.
MadridAges 18–75 - NCT07852728RecruitingPhase 2
Oxygen therapy for first responders after head injuries
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and overall well-being in first responders who have had a traumatic brain injury and still have symptoms. If you are a first responder dealing with ongoing brain injury symptoms, this study could help you find new ways to feel better.
Boise, IdahoAges 18–75 - NCT07851636Recruiting
Fast genetic testing to guide treatment for rare brain tumors
This trial tests a new way to pick treatments for rare brain tumors that have come back. Doctors will quickly analyze your tumor's genes and test drugs in the lab to find the best option for you.
Washington D.C., District of ColumbiaAges Up to 45 years - NCT05584267RecruitingPhase 2
Immunotherapy plus targeted brain radiation for lung cancer
This Phase 2 trial studies whether giving immunotherapy along with a precise form of brain radiation can control brain metastases from non-small cell lung cancer. It may help by shrinking or stabilizing spots in the brain while your body’s immune system is also activated.
Changsha, HunanAges 18 years+ - NCT07848594Recruiting
Temperature-regulating bed cover for sleep and health
This study tests whether a special temperature-regulating bed cover can improve sleep quality and reduce body inflammation, and how it affects gut health and your body's internal clock. You will use the bed cover and other devices at home, and provide blood and stool samples to see how your body responds.
Newton Center, MassachusettsAges 45 years+ - NCT07849465RecruitingPhase 2
Oxygen therapy for veterans with brain injury and lasting symptoms
This study tests whether breathing high-pressure oxygen (hyperbaric oxygen therapy) can help veterans who have had a traumatic brain injury (TBI) and are dealing with ongoing issues like memory or concentration problems. It also looks at whether this treatment affects certain markers in the blood that may relate to brain health.
Boise, IdahoAges 18–75 - NCT05780905RecruitingPhase 4
Semaglutide study for brain blood flow in type 2 diabetes
This trial tests whether semaglutide changes blood flow in the brain and the brain’s “barrier” (how well the brain is protected) in people with type 2 diabetes. It may help researchers understand brain-related effects of diabetes treatment using scans and blood tests.
Seattle, WashingtonAges 40–65 - NCT06374433Recruiting
How the brain learns: a brain stimulation study
This study explores how the brain learns and adapts (called brain plasticity) using a non-invasive brain stimulation technique. It may help understand learning and perception in healthy young adults.
MilanAges 18–35 - NCT06456814Recruiting
Study on how brain aneurysms form, grow, and rupture
This study looks at medical records from multiple hospitals in China to understand how brain aneurysms develop and when they might rupture. It may help researchers find better ways to predict and treat them.
GuangzhouAges 18–80 - NCT07838636Recruiting
Exercise program for people with Parkinson's and a deep brain stimulator
This study tests whether a structured physical activity program can improve movement and quality of life for people with Parkinson's who have a deep brain stimulator (DBS) device. Half the participants will do the exercise program, and half will continue usual care, to see if exercise helps manage symptoms.
WarsawAges 50–70 - NCT07835308RecruitingEarly Phase 1
Smart tuning of brain stimulation for better walking
This study is testing a new way to adjust deep brain stimulation (DBS) settings to improve walking in people with Parkinson's disease. If you have DBS and can walk with stimulation off, this trial may help fine-tune your treatment to improve your gait.
Minneapolis, MinnesotaAges 18 years+ - NCT07834476Enrolling by invitation
Setting treatment targets for severe head injury in children
This study looks at information from children who had a serious head injury. It uses data from special brain monitors to help doctors decide how to best manage these injuries.
Cambridge, CambridgeshireAges 1 month–18 years - NCT07831772Recruiting
Maintenance radiotherapy for newly diagnosed glioblastoma
This study tests an extra course of radiation therapy after standard treatment for glioblastoma, a type of brain cancer. The goal is to see if it helps keep the cancer from coming back.
Minneapolis, MinnesotaAges 18 years+ - NCT04842812RecruitingPhase 1
Personalized immune cell therapy for advanced solid tumors
This Phase 1 study tests engineered immune cells (TILs/CAR-TILs) made from your tumor to treat advanced solid cancers that have not responded to standard treatments. It may help your immune system better recognize and attack the cancer, but it is mainly focused on safety and early results.
GuangzhouAges 18–85 - NCT07824297Recruiting
Cognitive outcomes after brain blood vessel malformation treatment
This trial tests whether a minimally invasive procedure to block a specific type of abnormal connection between brain blood vessels can help preserve or improve memory and thinking. It is being studied in people who have not yet had bleeding from this condition.
BolognaAges 18–99 - NCT07817706Recruiting
A new noninvasive test for small bowel sensation
This study is developing a new, noninvasive test to measure how the small intestine senses stimulation. It aims to create a 'small intestine stress test' that may help better understand and someday diagnose gut sensitivity issues.
Rochester, MinnesotaAges 18–75
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,015 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.