Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05151718Recruiting
Study of ependymoma treatment resistance in children
This trial looks at why ependymoma can resist (be harder to treat) after radiation or treatment. It studies children who are already being followed in specific existing programs, which may help researchers find better treatment approaches in the future.
ToulouseAges Up to 25 years - NCT04648124Recruiting
MRI brain scan study in hereditary retinal vision loss
This study uses functional MRI (a type of brain scan) to understand how the brain processes vision in people with inherited retinal disorders. You might be included if you are an adult with hereditary retinal degeneration and are planning certain vision-related treatments soon.
Paris, PARISAges 18 years+ - NCT05124132Enrolling by invitation
Study of resilience and brain health after an earlier parent study
This trial looks at how resilience (how well people cope with stress) and brain health change over time in older adults who already joined an earlier study. You may be eligible if you participated in that “parent study.”
St Louis, MissouriAges 65 years+ - NCT04874220Recruiting
Brain study of real-world navigation in people with RNS
This study looks at how the brain works while people navigate in everyday life. It includes people who already have an RNS device placed in their brain and helps researchers understand the brain activity tied to spatial navigation.
Los Angeles, CaliforniaAges 12–70 - NCT05079516Recruiting
Study how the brain learns using arm testing and brain stimulation
This study uses a reaching task and a brain stimulation method (TMS) to see which brain areas help sensory learning. It may help researchers understand how learning works in the brain and how to design better therapies, if needed.
Bloomington, IndianaAges 18–45 - NCT04577911Recruiting
Brain study of social connection using MRI scans
This study looks at how social connection shows up in the brain using MRI, a type of scan. You may be able to take part if you can safely have an MRI and you’re not currently taking psychiatric medications.
New York, New YorkAges 18–65 - NCT04070040RecruitingPhase 2
Camrelizumab for returning brain lymphoma after prior treatment
This trial studies camrelizumab (an immune medicine) for primary CNS lymphoma that has come back after standard treatment. It aims to shrink the lymphoma seen on MRI and help control the disease with a new immune-based approach.
BeijingAges 18 years+ - NCT05589831Recruiting
Test breathing support and brain health in premature babies
This study checks how a type of breathing machine support affects brain health in very premature infants. It may help doctors choose safer breathing support strategies to protect the brain.
Toronto, OntarioAges 3 days+ - NCT05322239Recruiting
Brain stimulation study measuring resting brain activity
This trial tests how a specific brain stimulation method (theta burst stimulation) changes brain activity when you are resting. It may help researchers understand brain function changes, especially in people without certain mental or health risks.
Philadelphia, PennsylvaniaAges 18–60 - NCT05483465RecruitingPhase 4
NAD supplement trial for brain blood vessel health in aging
This trial studies whether taking an NAD supplement can support brain blood vessel health as people age. Participants will be tested for brain and health changes and may help researchers understand how to keep the brain’s blood vessels healthier over time.
Oklahoma City, OklahomaAges 60–85 - NCT04577677Recruiting
Study brain effects of mild electrical stimulation
This study looks at how mild electrical stimulation to the brain affects brain activity. You might be eligible if you’re generally healthy and can safely receive this stimulation, with no conditions that increase risk.
Leuven, Vlaams-BrabantAges 18–40 - NCT04165746Recruiting
Early care program for very young children in foster systems
This study looks at how an early support program affects the development of infants who are newly entering institutional care or foster care in the São Paulo area. It may help families and caregivers support healthy growth during a critical first period.
São Paulo, São PauloAges Up to 2 years - NCT04658628Recruiting
Brain scan study to learn who responds to spinal cord stimulation
This trial uses brain imaging to understand which people with long-lasting low back pain are more likely to benefit from spinal cord stimulation (SCS). If you’re being considered for an SCS trial, the scans may help researchers predict response and improve future care.
Los Angeles, CaliforniaAges 21 years+ - NCT04629469Recruiting
Two types of MRI scans in children
This study compares two MRI scan settings (a lower and higher magnetic field) in children to see how well they work for pediatric patients. It may help doctors choose the best MRI approach for kids without changing any care beyond the scan itself.
Kansas City, MissouriAges birth–22 years - NCT04085406Recruiting
Deep brain stimulation for hard-to-treat low back pain
This trial studies deep brain stimulation (DBS) to reduce severe low back pain that hasn’t improved after many standard treatments and procedures. It may help people whose pain is long-lasting and not fixable with another surgery.
Los Angeles, CaliforniaAges 40–75 - NCT04449523Recruiting
Check for hidden heart rhythm problems after silent brain strokes
This study looks at how often “silent” atrial fibrillation—an irregular heart rhythm that can be symptom-free—happens in people who have silent brain stroke spots on MRI. If it finds a link, it may help identify which patients might benefit from closer heart monitoring or prevention steps.
GrazAges 50 years+ - NCT04099056Recruiting
Brain scanning and stimulation to study decision-making
This trial uses brain scans and noninvasive brain stimulation to study how people make decisions. It may help researchers understand brain signals involved in choices and potentially improve future treatments.
Atlanta, GeorgiaAges 18–50 - NCT01617408Recruiting
Brain stimulation and vision testing in healthy adults
This study uses brain stimulation and brain imaging (MRI) along with vision tests to understand how the brain supports seeing. You might be eligible if you are a healthy adult and can safely complete MRI and stimulation tasks.
Bethesda, MarylandAges 18–50 - NCT03153670Recruiting
Brain scan study for people with deep brain stimulators
This study uses a 3‑tesla MRI (a type of detailed brain scan) in people who have deep brain stimulation (DBS) electrodes. The goal is to improve understanding of how the brain works; the scan is not meant to provide direct treatment benefit.
Toronto, OntarioAges 18–85 - NCT02509442Recruiting
Testing brain responses during awake brain surgery
This trial measures how the brain reacts to small electrical stimulation during an awake surgery for a specific type of brain tumor. It may help surgeons better plan and improve care for people having their first surgery for this tumor type.
MontpellierAges 30–50 - NCT03705715RecruitingPhase 1
Study brain immune-cell activity in different mental and brain conditions
This Phase 1 study looks for patterns (correlates) in how “microglial” brain immune cells become activated across different neuropsychiatric conditions and in healthy volunteers. It uses brain imaging to help researchers understand what might drive symptoms and differences between people.
Houston, TexasAges 18–80 - NCT07179848RecruitingPhase 1
Temporal interference brain stimulation safety study in healthy adults
This trial tests a new type of non-invasive brain stimulation that uses a weak electrical field to gently influence brain activity. It is designed for healthy adults to see if the procedure is safe and comfortable, and to gather information that could help develop future treatments for mental health conditions.
TaipeiAges 20–65 - NCT06517706Recruiting
Studying brain health after COVID-19
This study looks at how COVID-19 affects thinking and memory. It aims to understand and help people who still have brain fog or other cognitive issues after their infection.
Nicosia, CyprusAges 25–60 - NCT05843396Recruiting
Study of newborn brain development and response to care
This study looks at how newborns’ brains develop and how they respond to an intervention. It helps researchers understand brain organization in individual babies so care can improve in the future.
Minneapolis, MinnesotaAges Any age
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.