Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,015 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07485452RecruitingPhase 2
Boosting osimertinib's reach to the brain
This trial tests whether adding febuxostat helps the lung cancer drug osimertinib get into the brain better. It is for people with EGFR-mutated NSCLC who are already taking osimertinib, regardless of whether their cancer is stable or slowly progressing.
AmsterdamAges 18 years+ - NCT06709963Recruiting
Brain stimulation for older adults with chronic back or knee pain
This study tests a type of brain stimulation called intermittent theta burst stimulation to see if it can reduce pain and improve thinking in older adults with long-term back or knee pain. The treatment involves a non-invasive procedure that uses magnetic pulses to stimulate the brain.
Hong KongAges 60–85 - NCT06776458Recruiting
Aromatase inhibitor effects on heart and brain health in breast cancer
This study looks at how aromatase inhibitors (a type of hormone therapy for breast cancer) affect your heart and brain health over time. It compares women with breast cancer who have taken these drugs to healthy women of similar age.
Toronto, OntarioAges Any age - NCT05943756Recruiting
Well-being program for adults living with moderate to severe brain injury
This trial tests whether a well-being program can improve quality of life in adults with moderate to severe traumatic brain injury (TBI) more than a year after the injury. If you meet the language and medical-history requirements, you may be invited to join and complete program sessions and screening.
East Hanover, New JerseyAges 18 years+ - NCT07477613Recruiting
Brain implant for arm recovery after stroke
This trial tests a brain-computer interface (a device implanted in the brain) to help people who have had a stroke regain arm movement. It may help if you have a single stroke that happened 6 to 18 months ago and still have trouble using your arm.
GrenobleAges 18–70 - NCT07473505Recruiting
Nerve block for PTSD in special operations veterans
This study tests if a specific nerve block (cervical sympathetic block) can help reduce trauma-related symptoms in Special Operations veterans with PTSD. The goal is to see if this treatment is safe and can improve how you feel.
Strongsville, OhioAges 18 years+ - NCT07477821Recruiting
Muscle and brain health study in aging and neurological disorders
This study looks at the link between muscle health and brain function in people with different neurological conditions or healthy aging. It may help researchers understand how muscle changes relate to memory, movement, and thinking problems.
CataniaAges 60 years+ - NCT07476781Recruiting
Liquid biopsy study for solid tumours and brain tumours
This study collects samples of spinal fluid and blood from people with solid tumours that have spread to the brain or spine, or who have primary brain tumours. The goal is see if these samples can help doctors detect and monitor these cancers more easily.
Toronto, OntarioAges 18 years+ - NCT06626308Recruiting
Early signs in Huntington’s gene carriers study
This study looks for early changes in the body and brain of people who carry the Huntington’s disease gene but don’t yet have symptoms. It may help find better ways to track the disease early.
GrenobleAges 18–70 - NCT05968053Recruiting
Testing microplastics detection in neurosurgery patients
This study checks whether microplastics and nanoplastics can be detected in people undergoing neurosurgery. If it works, it could help doctors better understand possible material exposures around brain and nerve procedures.
Beijing, Beijing MunicipalityAges 18–80 - NCT07464925RecruitingPhase 1
Testing GLIX1 for adults with returning high-grade glioma
This trial tests a new drug called GLIX1 to find a safe dose for people whose high-grade glioma (a fast-growing brain tumor) has come back or is getting worse after earlier treatments. It may be an option if you've had no more than two prior treatments.
Tampa, FloridaAges 18 years+ - NCT07466589Recruiting
Electric stimulation for dizziness after concussion
This trial tests if a portable electric stimulation device can help improve balance and reduce dizziness in people recovering from a concussion. If you have had ongoing imbalance for at least 4-6 weeks, this study may help you feel steadier.
Ann Arbor, MichiganAges 18–55 - NCT07466290Recruiting
L-serine with strength training for seniors
This trial tests whether taking a supplement called L-serine along with a strength training program can improve muscle strength and function in older adults. It might help you stay strong and independent.
Vienna, State of ViennaAges 65–85 - NCT07469566Recruiting
Studying the natural course of 7q11.23 microduplication syndrome
This study follows people with a rare genetic condition called 7q11.23 microduplication over time to understand how it affects development, learning, and health. Participants will have interviews, thinking and memory tests, and an MRI brain scan.
BronAges 5–50 - NCT07469384Recruiting
Brain stimulation study for schizophrenia using tDCS
This study tests whether a mild form of brain stimulation called tDCS (transcranial direct current stimulation) can help improve symptoms of schizophrenia or schizoaffective disorder. tDCS uses small electrodes on the scalp to gently stimulate brain areas involved in vision and thinking.
Orangeburg, New YorkAges 18–55 - NCT06710249RecruitingPhase 2
Testing Salovum and SPC Flakes for Brain Tumor Swelling
This trial tests whether two special food products (Salovum and SPC Flakes) can help reduce brain swelling caused by tumors. If you have a brain tumor with swelling and are already on steroids, you may be able to join.
LundAges 18–79 - NCT06792877Recruiting
Mindfulness for thinking in early Alzheimer's
This study tests if mindfulness training can help protect thinking and memory in early-stage Alzheimer's disease. It compares mindfulness to other activities to see if it slows down memory loss.
Boston, MassachusettsAges 50–100 - NCT07459699Recruiting
Probiotics for kids with mild ADHD
This study tests whether a probiotic supplement can help children with mild ADHD by improving communication between the gut and the brain. It may offer a natural way to support focus and behavior.
ShanghaiAges 8–11 - NCT05097001Recruiting
Personalized brain-stimulation program for dystonia using imaging
This study tests whether using brain imaging to guide stimulation settings can improve symptoms in people with long-term deep brain stimulation for dystonia. It will compare different stimulation approaches in a blinded, step-by-step crossover design to see which one helps more.
Würzburg, BavariaAges 18 years+ - NCT06374667Recruiting
Skull bone injection vs. IV for large stroke
This trial tests a new way to give medicine for a large stroke on one side of the brain. The medicine is injected into the skull bone instead of through a vein, and researchers want to see if it works better and is safe.
Wuhu, AnhuiAges 18–80 - NCT07461584Recruiting
Memory boost in older adults with optimal dosing
This study tests a safe, non-invasive brain stimulation method to see if it can improve memory in healthy older adults. It uses carefully chosen doses to find the best approach.
Boston, MassachusettsAges 65 years+ - NCT07458308Enrolling by invitation
Blended care vs. traditional rehab after stroke or brain injury
This trial compares a new approach that combines in-person therapy with digital support to standard outpatient rehabilitation for people recovering from stroke or brain injury. The goal is to see if blended care works as well or better than traditional rehab.
LucerneAges 18–80 - NCT07455760Recruiting
Deep brain stimulation and speech sequencing study
This study looks at how deep brain stimulation affects speech in people with Parkinson's disease or essential tremor. It tests whether the stimulation changes the way you say sequences of sounds.
Boston, MassachusettsAges 18 years+ - NCT07454473RecruitingPhase 4
Edaravone and Dexborneol for chemo-related memory loss
This trial tests if a sublingual tablet can help people who have memory and thinking problems related to chemotherapy. If you have had certain types of chemotherapy and now notice trouble with your memory or concentration, this treatment might help improve your symptoms.
Shenyang, LiaoningAges 35–80
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,015 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.