Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,015 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07549997RecruitingPhase 1
Social Participation Recovery Program After Brain Injury
This study tests whether a group program can help people who've had a traumatic brain injury (TBI) get back to social activities they enjoyed before their injury. You'll work with others and learn strategies to re-engage with friends, family, and community.
St Louis, MissouriAges 18 years+ - NCT05641948Recruiting
Tested nerve ablation plus brain scans for ongoing back pain
This trial studies a procedure called radiofrequency denervation to reduce long-lasting, mostly “pain-from-joints/structures” low back pain, and it uses brain imaging to understand what changes during treatment. It may help people who already showed they respond well to a similar diagnostic nerve block.
Aberdeen, ScotlandAges 18 years+ - NCT07534319Recruiting
Brain Blood Flow Changes After Stroke Clot Removal
This study examines how blood flow in the brain changes after a minimally invasive procedure to remove a blood clot during an acute stroke. The research uses MRI imaging to understand brain recovery patterns and may help improve stroke treatment outcomes.
Zurich, Canton of ZurichAges 18 years+ - NCT07541781RecruitingPhase 1
Sitagliptin for recurrent grade 4 glioma
This trial tests whether the diabetes drug sitagliptin (Januvia) can help slow or shrink a recurrent grade 4 glioma (a type of brain tumor). It's for people whose tumor has come back after standard treatment and who have not used sitagliptin or Avastin before.
Iowa City, IowaAges 18 years+ - NCT07535593RecruitingPhase 2/Phase 3
Electrical Acupoint Stimulation for Consciousness Disorders
This trial tests a non-invasive treatment called transcutaneous electrical acupoint stimulation (TEAS) to help people recover consciousness after severe brain injury. The treatment uses mild electrical pulses on specific points on the hands and may help improve awareness and responsiveness.
Xi'an, ShaanxiAges 18–80 - NCT06752434Recruiting
Comparing two brain stimulation methods for dystonic tremor
This trial compares PSA (a type of deep brain stimulation targeting a different brain area) versus traditional STN DBS for treating dystonic tremor. It aims to see which method provides better tremor control with fewer side effects.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07526740Recruiting
Brain Stimulation and Training for Mild Memory Loss
This study tests whether combining brain stimulation (TMS) with cognitive training games can help people with mild cognitive impairment—early memory and thinking problems. The goal is to see if this combination improves thinking abilities and slows cognitive decline.
Charleston, South CarolinaAges 60–85 - NCT04911452Recruiting
Calmer NICU care for very preterm babies
This study tests a calmer approach in the NICU to help very preterm babies grow and develop their brains. It may be helpful if your baby needs breathing support and is in the early weeks of life.
Vancouver, British ColumbiaAges 6 months–7 months - NCT07517172Recruiting
Brain Stimulation Patch for Jaw Pain: Home Treatment Study
This study tests whether a small, stick-on electrical patch placed on your ear can reduce temporomandibular disorder (TMD) jaw pain when used at home. You would apply the patch yourself and complete surveys about your pain to help researchers learn if this non-invasive approach is safe and feasible.
Minneapolis, MinnesotaAges 18–65 - NCT07521930Recruiting
Brain implant to restore communication and movement control
This trial tests a surgically implanted brain device designed to help people with severe paralysis or movement disorders regain the ability to communicate and control their limbs. The device reads signals from your brain and translates them into commands that could help you interact with computers or assistive technology.
Baltimore, MarylandAges 18–80 - NCT07521384Enrolling by invitation
Real-World Study of Intranasal Cell Therapy for Brain Injuries
This study follows people who receive intranasal stem cell or exosome therapy (tiny packages from special cells) for brain or neurological conditions like stroke, brain injury, or cerebral palsy. Researchers track how well the treatment works by measuring inflammation markers in the blood and monitoring clinical improvements over time.
Monterrey, Nuevo LeónAges 4–80 - NCT07512154Recruiting
Precision Brain Tumor Radiotherapy Using Advanced MRI
This study tests a new way to plan and deliver radiation therapy for glioblastoma (an aggressive brain tumor) using special MRI scans to target cancer cells more precisely. The goal is to improve treatment effectiveness while reducing harm to healthy brain tissue.
Baltimore, MarylandAges 18 years+ - NCT07509944Recruiting
Brain activity in stroke patients during mirror movement
This study uses a brain imaging technique called functional near-infrared spectroscopy (fNIRS) to look at how the brain works when stroke patients perform mirror movements. It aims to help understand brain recovery after a first-time stroke.
HangzhouAges 18–75 - NCT07516028Recruiting
How Your Brain Responds to Low Oxygen Levels
This study looks at how your brain's nerve signals change when exposed to moderate low-oxygen conditions. Researchers will use brain stimulation and imaging to understand these changes, which could help future treatments for brain and spinal cord conditions.
Loos, Hauts-de-FranceAges 18–65 - NCT06553235Recruiting
App-based sleep and memory help for breast cancer survivors
This study tests whether an app-based program can improve sleep and thinking problems (like concentration and memory) in people who finished breast cancer treatment 1-5 years ago. If you have trouble sleeping and/or notice changes in your memory or focus, this trial may be able to help.
Aarhus NAges 18 years+ - NCT07506239Recruiting
Laser therapy for low-grade brain tumors in young people
This trial tests a laser treatment called LITT for low-grade glioma (a type of brain tumor) that has come back or is growing despite prior treatment. It aims to see if the laser is safe and effective in young people aged 2 to 25.
San Francisco, CaliforniaAges 2–25 - NCT07503717Recruiting
Brain scan surveillance in HER2-positive metastatic breast cancer
This study tests whether regular brain scans (surveillance) help spot brain metastases early in people with HER2-positive breast cancer that has spread to other parts of the body. Participation involves being randomly assigned to either routine brain scans or no extra scans to see which approach is better.
BeaumontAges 18 years+ - NCT05528939Recruiting
Training attention skills for children after cancer
This trial tests a computer-based “attention-control training” program to see if it’s doable and helpful for children who finished treatment for acute lymphoblastic leukemia or a brain tumor. It also looks at how acceptable the program is for both kids and caregivers.
Washington D.C., District of ColumbiaAges 8–16 - NCT07493096Recruiting
Intensive therapy program for children with brain-based conditions
This trial tests an intensive therapy program designed to help children with brain-based conditions like cerebral palsy or autism improve their skills in movement, thinking, and daily activities. The program runs for 2 weeks with daily sessions, and researchers will check for changes in your child's abilities.
The Woodlands, TexasAges 4–12 - NCT07497347Recruiting
Amino acids and lifestyle for brain aging in older adults
This study tests whether taking a specific amino acid supplement, along with lifestyle changes, can help slow or improve brain aging in older adults who have mild depression. It aims to see if these nutrients can support brain health and mood.
BresciaAges 65–85 - NCT07496918RecruitingPhase 2
Brain effects of light and sound stimulation at 40 Hz
This study tests whether special lights and sounds (at a specific 'gamma' frequency) can safely affect brain activity. It is an early trial looking at how the brain responds to these gentle sensory stimulations.
Cambridge, MassachusettsAges 18–100 - NCT07492472Recruiting
Low-intensity music for anxiety in young adults
This trial tests whether listening to low-intensity music can help ease anxiety in young adults. If you join, you will answer some questions about your symptoms while the study also measures things like your voice, heart rate, and brain activity.
Haikou, HainanAges 18–25 - NCT05697159Recruiting
7-tesla brain MRI to study how filgotinib eases RA pain
This trial uses a very high-strength brain MRI to understand how the RA medicine filgotinib may reduce pain. If you have active rheumatoid arthritis and can safely complete the scan, the study may help researchers better target pain relief in RA.
GlasgowAges 18–74 - NCT07485452RecruitingPhase 2
Boosting osimertinib's reach to the brain
This trial tests whether adding febuxostat helps the lung cancer drug osimertinib get into the brain better. It is for people with EGFR-mutated NSCLC who are already taking osimertinib, regardless of whether their cancer is stable or slowly progressing.
AmsterdamAges 18 years+
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,015 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.