Clinical trials
Breast Cancer Stage I clinical trials
Below are recruiting breast cancer stage i clinical trials, each written for real people, not researchers. We’re tracking 1,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06532955Recruiting
Robot-assisted surgery for arm swelling after breast cancer
This trial tests a robotic surgical technique to reconnect tiny lymph vessels and reduce arm swelling (lymphedema) in women who had breast cancer treatment. It may help if your swelling is still in the early stages.
Maastricht, LimburgAges 18 years+ - NCT06023576RecruitingPhase 2
Blood pressure control during breast cancer chemo
This study tests whether careful blood pressure management can help protect the heart during certain types of chemotherapy (anthracyclines) for breast cancer. Participants will use a smart blood pressure device and may also do an exercise test.
Basking Ridge, New JerseyAges 18 years+ - NCT07297927Recruiting
Imaging lymph flow before and after radiation for breast cancer
This study looks at how a special imaging test (lymphoscintigraphy) can show changes in the lymphatic system before and after radiation therapy for breast cancer. It aims to help predict and prevent lymphedema, a common side effect that causes arm swelling.
Hwaseong-si, GyeonggidoAges 18 years+ - NCT07300995Recruiting
Pain coping skills for older women with breast cancer
This study tests a behavioral program to help older women with breast cancer learn skills to cope with pain. The program is done through video or phone sessions.
Durham, North CarolinaAges 55 years+ - NCT07757763Recruiting
Slow jogging for breast cancer survivors
This study looks at whether slow jogging (a gentle form of running) can help breast cancer survivors sleep better. You'll be asked to use a smartphone app to track your activity and sleep, and you may be assigned to a jogging group or a usual-care group.
Taipei, Taipei CityAges 20 years+ - NCT04983121RecruitingPhase 2
Neoadjuvant pyrotinib plus ARX788 for HER2-positive breast cancer
This Phase 2 trial studies whether combining pyrotinib with ARX788 given before surgery can work better and be safe in people with HER2-positive breast cancer. It’s designed for tumors that did not respond well enough to earlier trastuzumab and pertuzumab treatment.
Shenyang, LiaoningAges 18–75 - NCT05494502Recruiting
Nerve block to reduce long-term pain after breast surgery
This trial tests whether a specific pain-numbing nerve block given during mastectomy can reduce chronic (long-lasting) pain after breast cancer surgery. It may help some people use less pain medicine later by lowering nerve-related pain after surgery.
Beijing, Beijing MunicipalityAges 18–85 - NCT05684367Recruiting
Exercise program to rebuild stamina and energy after breast cancer
This study tests whether a structured exercise program can help older adults with breast cancer regain stamina and reduce fatigue. It focuses on people who are still dealing with moderate fatigue after finishing certain breast cancer treatments.
Gainesville, FloridaAges 60–105 - NCT05723250Recruiting
Rural early cancer care coaching and education program
This study tests an educational “care coordination” program to help people living in rural Vermont manage care during the early stages of breast, lung, or colon cancer treatment. It may help you feel more supported and organized while starting or preparing for chemotherapy.
Burlington, VermontAges 18 years+ - NCT05899387Recruiting
Study fluid after breast surgery
This study looks at a problem called seroma, which is fluid buildup, after certain breast surgeries. It compares different situations where implants or tissue expanders are used, to better understand what to expect and how to manage it.
Augsburg, BavariaAges 18 years+ - NCT06274034RecruitingEarly Phase 1
Muse headband study for anxiety and sleep in breast cancer survivors
This study tests if a headband that guides meditation can help breast cancer survivors with anxiety and trouble sleeping. You wear the headband for short sessions and track your progress on a phone or tablet.
Rochester, MinnesotaAges 18–80 - NCT06336928Recruiting
Blood test validation for breast cancer diagnosis
This study is testing a new blood test (liquid biopsy) to see if it can accurately detect breast cancer or track remission. If you are a woman getting a mammogram, have an abnormal finding, were recently diagnosed, or are in remission after treatment, you may be able to join and help validate this test.
Los Angeles, CaliforniaAges 18 years+ - NCT06955702Recruiting
Cryotherapy to Prevent Eyelash Loss from Chemo
This trial tests if cooling the eyelids during chemotherapy can prevent eyelash loss in women with newly diagnosed breast cancer. It is for those who have not yet started treatment.
Santander, CantabriaAges 18 years+ - NCT02897700RecruitingPhase 1
Testing chemotherapy choices for early breast cancer after surgery
This Phase 1 study tests different chemotherapy approaches in people with breast cancer that has been surgically removed but is early stage. It aims to find a chemotherapy plan that’s safe and works well right after surgery.
Ganzhou, JiangxiAges 18 years+ - NCT07465393Recruiting
Facility rehab vs home exercise for breast cancer survivors
This trial compares two types of exercise programs for breast cancer survivors to see which one improves quality of life more. You will either attend supervised rehab sessions at a facility or follow a resistance exercise program at home.
New Taipei City, Xindian DistAges 18 years+ - NCT07472803Recruiting
Body composition study in early breast cancer patients
This study looks at how body composition (muscle and fat) changes over time in people with early-stage breast cancer. It aims to better understand the effects of cancer treatment on the body.
New Taipei City, Xindian DistAges 18 years+ - NCT06966700RecruitingPhase 3
Study of Sac-TMT in Early High-Risk Breast Cancer
This study tests a new drug called Sacituzumab Tirumotecan (Sac-TMT) for people with early-stage, high-risk breast cancer that hasn't spread. The drug is given before surgery to see if it can shrink tumors and improve outcomes.
Gilbert, ArizonaAges 18 years+ - NCT06524895Recruiting
Reiki for women having breast surgery
This trial tests if Reiki, a gentle hands-on relaxation technique, can improve quality of life for women undergoing mastectomy for breast cancer. If you are having a mastectomy and live near the Bronx, you may be eligible.
The Bronx, New YorkAges 18–99 - NCT07091305RecruitingPhase 2
Study of a new drug with chemotherapy for limited-stage small cell lung cancer
This trial tests an investigational drug called QL1706 combined with chemotherapy, given after standard chemoradiation, for people with limited-stage small cell lung cancer. The goal is to see if this combination helps keep the cancer from coming back.
ShanghaiAges 18–75 - NCT06509126RecruitingPhase 3
Panitumumab with Chemo: Continuous or Intermittent for Advanced CRC
This trial compares giving panitumumab plus FOLFIRI (two chemotherapy drugs) either continuously or with breaks, as a first treatment for left-sided colorectal cancer that has spread. It's for people whose tumors have certain genetic markers (RAS/BRAF wild-type) and haven't had treatments for advanced disease before.
NaplesAges 18–100 - NCT07454499Recruiting
Symptom monitoring and health for women on hormone therapy for breast cancer
This trial tests a mobile health program to help women manage symptoms and stay healthy while taking hormone therapy (like tamoxifen or anastrozole) for early-stage breast cancer. It involves using a smartphone app and an electronic pill bottle to track your health and medication.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05706129RecruitingPhase 1/Phase 2
Testing targeted imaging and therapy for advanced solid tumors
This early-phase study tests two radioactive medicines that first help doctors see tumors and, in some parts of the study, treat them. It may help people with advanced, hard-to-remove cancers that have a specific tumor marker (CA IX).
MelbourneAges 18 years+ - NCT07427186Recruiting
Studying how immunotherapy affects the immune system in early-stage cancer
This trial looks at how your immune system responds to immunotherapy given before surgery for early-stage solid tumors (like lung, head and neck, melanoma, or bladder cancer). The goal is to understand why some people respond better, so doctors can improve treatment for future patients.
ToulouseAges 18 years+ - NCT07765927Recruiting
Exercise program for people with breast or gynecologic cancer
This study is testing whether an exercise program for people with breast or gynecologic cancer is feasible to run. It aims to see if patients can participate and follow the program.
Iowa City, IowaAges 18 years+
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Common questions
- Are there clinical trials for breast cancer stage i?
- Yes. Clin2 currently lists 1,196 recruiting breast cancer stage i studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer stage i trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer stage i trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Anatomic Stage IV Breast Cancer AJCC v8
- Anatomic Stage III Breast Cancer AJCC v8
- Anatomic Stage II Breast Cancer AJCC v8
- Anatomic Stage I Breast Cancer AJCC v8
- Early-stage Breast Cancer
- Breast Cancer Stage III
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.