Clinical trials
Breast Cancer Surgery clinical trials
Below are recruiting breast cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 1,189 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06468566Recruiting
New imaging test for breast lumps using sound and light
This study tests a new kind of imaging that uses sound waves and light to tell if a breast lump is benign (not cancer) or malignant (cancer). It could help avoid unnecessary biopsies.
Wuhan, HubeiAges 18–85 - NCT07361562RecruitingPhase 1
Study of CGT4255 for advanced solid tumors with HER2 changes
This trial tests an oral drug called CGT4255 for people with advanced solid tumors that have certain changes in the HER2 gene or related proteins. It aims to see if the drug is safe and effective.
Grand Rapids, MichiganAges 18 years+ - NCT06556654Recruiting
Tissue reinforcement for breast reconstruction study (REDEFINE)
This study tests a new tissue reinforcement device (like a mesh) used during two-stage implant-based breast reconstruction after a mastectomy. It is designed for women having their first reconstruction and may help support the implant and improve healing.
Scottsdale, ArizonaAges 22 years+ - NCT07187726Recruiting
Trial to predict arm swelling risk during breast cancer radiation
This trial checks if telling you about your personal risk of arm swelling (based on a computer prediction) helps prevent it. You'll wear a compression sleeve during radiation and be monitored closely.
ArrasAges 18 years+ - NCT07650305Recruiting
Pain Relief Methods After Breast Cancer Surgery
This trial compares two different nerve-blocking techniques (numbing methods) to reduce pain after breast cancer surgery. Both approaches aim to keep you comfortable during and after your operation.
CairoAges 18–65 - NCT06022029RecruitingPhase 1
Study of injected ONM-501 alone or with cemiplimab for advanced cancers
This trial tests an injected study drug (ONM-501) alone or with another drug (cemiplimab) for people with advanced solid tumors or lymphomas that haven't responded to other treatments. It aims to find a safe dose and see if the combination helps shrink or control the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT06033287Recruiting
Real-world study of CDK4/6 inhibitors plus hormone therapy for advanced breast cancer
This study looks at how well CDK4/6 inhibitors combined with hormone therapy work in real-world settings for people with a certain type of advanced breast cancer (HR+/HER2-). It aims to understand the best treatment path and what happens next.
Changsha, HunanAges 18 years+ - NCT06888258Recruiting
Comparing two nerve blocks for pain after breast cancer surgery
This study compares two types of nerve blocks for pain relief after breast cancer surgery. It will help determine which block works better to reduce pain and the need for strong pain medicines after a mastectomy.
CairoAges 18–60 - NCT02743858Recruiting
Watch swelling study after breast lymph node surgery
This study looks at how and when swelling (lymphedema) happens after breast cancer surgery on the armpit lymph nodes. You may be followed closely after your planned one-sided procedure to better understand who gets swelling and how it changes over time.
Basking Ridge, New JerseyAges 18 years+ - NCT05255471RecruitingPhase 3
Olaparib after surgery for recurrent ovarian cancer
This trial tests whether olaparib (a pill cancer medicine) works better than standard platinum chemotherapy after a second surgery for recurrent ovarian cancer. It’s for people whose cancer returned after initial PARP-inhibitor (PARPi) maintenance and aims to see if treatment can control the cancer for longer with acceptable side effects.
NaplesAges 18 years+ - NCT07738770Recruiting
Comparing two numbing techniques for pain relief after mastectomy
This trial tests two different numbing injections to see which one works better for pain after breast cancer surgery. If you are having a mastectomy, you may be able to join and help find a better way to manage pain.
Jakarta, DKI JakartaAges 18–60 - NCT05361837Recruiting
Nerve block with sedation for breast surgery comfort
This trial tests if adding a numbing injection (serratus anterior plane block) with a calming medicine (dexmedetomidine) helps reduce pain during and after breast removal surgery.
Cairo, Cairo GovernorateAges 18–65 - NCT05708235RecruitingPhase 2
Blood test monitoring for early breast cancer recurrence
This trial uses a blood test to look for tiny bits of tumor DNA after treatment. If found, participants receive new drug combinations to try to prevent cancer from returning.
A CoruñaAges 18 years+ - NCT06393374RecruitingPhase 3
Study of a new drug combination for residual TNBC after initial treatment
This trial tests a new combination of two drugs (sacituzumab tirumotecan and pembrolizumab) compared to standard chemotherapy for people with triple-negative breast cancer that did not fully respond to initial treatment. It aims to see if this combination helps prevent cancer from coming back.
Mobile, AlabamaAges 18 years+ - NCT06467149Recruiting
Comparing Frailty Screenings in Older Breast Cancer Patients
This study compares different ways to check frailty (a measure of how well your body handles stress) in women with breast cancer who are 50 or older. The goal is to find which screening tool best predicts health outcomes during treatment.
ChongqingAges 50 years+ - NCT05232916RecruitingPhase 3
Vaccine for HER2-positive breast cancer after standard treatment
This trial tests a vaccine (GLSI-100) that may help prevent the return of HER2-positive breast cancer. It is given to patients who still had cancer cells after initial treatment with trastuzumab, or who had stage III disease and achieved a complete response.
Mobile, AlabamaAges 18–100 - NCT06750484RecruitingPhase 2
Testing trastuzumab deruxtecan in HER2-zero breast cancer
This trial tests a new drug called trastuzumab deruxtecan (a targeted antibody-drug combination) for people with advanced breast cancer that never showed any HER2 protein (HER2-zero). The goal is to see if it can shrink tumors and improve outcomes for those who have already had standard treatments.
New Haven, ConnecticutAges 18 years+ - NCT04819243RecruitingPhase 2
Test a BRCA-targeted drug plan for advanced ER-positive breast cancer
This Phase 2 study tests how well a treatment plan using palbociclib followed by talazoparib (and possibly atezolizumab) works in certain people with advanced ER-positive breast cancer. It may help by targeting cancer biology linked to BRCA/HRD changes and by strengthening how the cancer is controlled.
Seoul, Gannam-guAges 19 years+ - NCT03562273Recruiting
GammaPod planning study for breast cancer quality of life
This study looks at how GammaPod radiation planning after a lumpectomy affects quality of life and comfort. Your doctors will use imaging and a structured plan to help predict outcomes and refine care.
Bel Air, MarylandAges 18 years+ - NCT06754059Recruiting
Pyrotinib with trastuzumab for HER2-positive breast cancer maintenance
This trial tests a combination of two targeted drugs (pyrotinib and trastuzumab) as maintenance therapy to keep HER2-positive breast cancer that has spread under control. It is for women who have already received some first-line treatment and are stable enough to continue therapy.
Fuzhou, FujianAges 18–70 - NCT07071896Recruiting
Video exercise program for breast cancer survivors
This study tests a video-based exercise program for people who recently had breast cancer surgery. It aims to help with recovery by providing guided exercises you can do at home.
San Diego, CaliforniaAges 18 years+ - NCT06607757RecruitingPhase 2
Capivasertib plus fulvestrant for high-risk lobular breast cancer
This trial tests adding capivasertib to fulvestrant for women with a certain type of breast cancer (invasive lobular carcinoma) that is hormone-receptor positive and has a high risk of coming back. The treatment is given before surgery to see if it works better than fulvestrant alone.
AugsburgAges 18 years+ - NCT07708571Recruiting
Coaching program for women on ribociclib and aromatase inhibitor
This study tests whether a coaching program based on personality types helps women with early-stage hormone receptor-positive, HER2-negative breast cancer stick to their treatment plan. Participants must be taking ribociclib (Kisqali) and an aromatase inhibitor, and their cancer must not have spread to other organs.
Augsburg, BavariaAges 18 years+ - NCT07607366Recruiting
Negative Pressure Bandaging After Breast Removal Surgery
This trial tests a special bandage that uses gentle suction to help wounds heal better after breast cancer surgery. Researchers want to see if this type of bandaging reduces complications like fluid buildup and improves healing.
FalunAges 18 years+
Hear when a new Breast Cancer Surgery trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for breast cancer surgery?
- Yes. Clin2 currently lists 1,189 recruiting breast cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.