Clinical trials
Breast cancer clinical trials
Cancer that forms in the cells of the breast, the most common cancer in women. We’re tracking 2,478 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06739655Recruiting
Radiation before surgery with breast reconstruction
This trial tests whether giving radiation therapy before surgery (instead of after) is safe and effective for women with breast cancer who also want immediate breast reconstruction. It could help avoid the need for a second surgery and improve recovery.
Edegem, AntwerpenAges 18 years+ - NCT06744465Recruiting
Light-based monitoring for breast cancer during chemo
This study uses a special light-based device to monitor breast cancer during chemotherapy before surgery. It is for women with HER2-positive or triple-negative breast cancer who are planning chemotherapy first.
Indianapolis, IndianaAges 18 years+ - NCT06746688RecruitingPhase 1
Safety study of ES2B-C001 for HER2-positive metastatic breast cancer
This trial tests a new drug called ES2B-C001, with or without an adjuvant, to see if it is safe for people with HER2-positive breast cancer that has spread and has not responded to previous treatments.
GrazAges 18 years+ - NCT06756932RecruitingPhase 1
Bcl-2 inhibitor combo for advanced HR+ breast cancer
This trial tests a new Bcl-2 inhibitor (BGB-21447) combined with other therapies for advanced HR+/HER2- breast cancer that has already been treated with hormone therapy and a CDK4/6 inhibitor. It aims to see if these combinations are safe and effective.
Iowa City, IowaAges 18 years+ - NCT06762496Recruiting
A tool to help you stay involved in your breast cancer care
This study is testing a new tool designed to help you take a more active role in your healthcare journey. It's for people with early-stage breast cancer that can be surgically removed.
Milan, ItalyAges 18 years+ - NCT06765590Recruiting
Paclitaxel (albumin-bound) bioequivalence study in breast cancer
This study tests whether a new version of paclitaxel (albumin-bound) works the same as the approved version in people with breast cancer. It's for patients whose cancer has spread or returned after other treatments, or those for whom this drug is recommended by treatment guidelines.
Luoyang, HenanAges 18–75 - NCT06768931RecruitingPhase 2
Combination therapy before surgery for triple-negative breast cancer
This trial tests adding an immunotherapy drug to standard chemotherapy before surgery for triple-negative breast cancer. The goal is to see if this combination works better than chemotherapy alone.
Lanzhou, GansuAges 18 years+ - NCT06772935Recruiting
Acupuncture for nerve pain from breast cancer chemo
This trial tests if electroacupuncture can help with nerve pain or numbness caused by taxane chemotherapy for breast cancer. It may offer relief for ongoing symptoms after treatment.
Xining, QinghaiAges 18–75 - NCT06773897Recruiting
Genetics of Breast Cancer Study
This study looks at the genetics of breast cancer by collecting DNA from a saliva sample and asking you to fill out a health survey online. It's open to anyone in the U.S. who is 18 or older and can complete the study materials in English.
Piscataway, New JerseyAges 18 years+ - NCT06774027Recruiting
Breast cancer antibody-drug conjugate treatment registry
This study tracks how well antibody-drug conjugates (ADCs) work for breast cancer that has spread. You may join if you are about to start your first or second ADC for hormone receptor-positive/HER2-negative or triple-negative breast cancer.
San Francisco, CaliforniaAges 18 years+ - NCT06777420Recruiting
Question list for breast cancer patients before chemo
This study tests whether a list of helpful questions can improve communication and care for breast cancer patients who will receive chemotherapy before surgery. It aims to support patients in talking with their doctors about what matters most to them.
Uppsala, Region UppsalaAges 18 years+ - NCT06780176Recruiting
Breast cancer risk study for people in Florida
This study looks at breast cancer risk factors and outcomes by inviting people who are getting breast biopsies or are new breast patients at certain Florida hospitals to complete a survey. It aims to better understand what affects breast cancer risk and treatment results.
Los Angeles, CaliforniaAges 18 years+ - NCT06780735Recruiting
Breast-sparing surgery using a special dye after chemo
This trial tests a technique where doctors use a special dye (ICG) to guide breast-conserving surgery in patients whose tumors have shrunk enough after chemotherapy. The goal is to remove only the cancer while saving as much healthy breast tissue as possible.
Goyang-si, Gyeonggi-doAges 18 years+ - NCT06780748RecruitingPhase 2
Light-guided re-surgery for recurrent breast cancer
This trial uses a special light and dye to help surgeons find and remove lymph nodes that might contain cancer cells, in women whose breast cancer has come back in the same area after previous surgery.
Goyang-siAges 18 years+ - NCT06781762Recruiting
Breast cancer hormone therapy and its effects on heart and brain
This study looks at how starting a common hormone therapy for breast cancer (aromatase inhibitors) affects your heart and brain health over the short term. It compares women starting this treatment to healthy women who are not on the therapy.
Toronto, OntarioAges Any age - NCT06781996RecruitingPhase 3
Digital tool to help manage hormone therapy side effects
This trial tests a digital tool (a smartphone app) to help women and men with early breast cancer manage side effects from hormone therapy. The goal is to improve quality of life during treatment.
VillejuifAges 18 years+ - NCT06784921Recruiting
Study of sacituzumab govitecan for HER2-negative breast cancer
This study looks at how well a drug called sacituzumab govitecan works and how safe it is for people with a certain type of breast cancer that has spread (HER2-negative metastatic breast cancer). It aims to understand real-world results for patients in China.
Hangzhou, ZhejiangAges 18–75 - NCT06786949Recruiting
Night shift work and breast cancer risk study
This study looks at whether working night shifts is linked to breast cancer in female health workers. It aims to understand if there is a higher risk for those who work nights.
BolognaAges 20–70 - NCT06797635RecruitingPhase 2
Study of Patritumab Deruxtecan and Pembrolizumab for High-Risk Early Breast Cancer
This trial tests a combination of targeted therapies (patritumab deruxtecan plus pembrolizumab) along with other anticancer drugs for people with a high-risk type of early-stage breast cancer that is either triple-negative or has very low hormone receptors and is HER2-negative. The goal is to see if this approach can help prevent the cancer from coming back.
Santa Monica, CaliforniaAges 18 years+ - NCT06800612Recruiting
Cancer drug therapy study for gynecologic or breast cancers
This study looks at how well different cancer drugs work for women with breast or gynecologic cancers. Researchers will review medical records to see how patients responded to treatment over time. If you have been treated for breast or gynecologic cancer since 2010, you may be eligible.
BolognaAges 18 years+ - NCT06800989Recruiting
Can sophrology with a wearable device reduce chemo anxiety?
This study tests whether a relaxation technique called sophrology, guided by a wearable device, can help reduce anxiety during chemotherapy for early-stage breast cancer. It aims to offer extra support during treatment.
AngersAges 18 years+ - NCT06802757RecruitingPhase 2
Study of posaconazole with immunotherapy and chemo for triple-negative breast cancer
This trial tests if adding posaconazole (an antifungal drug) to standard immunotherapy and chemotherapy before breast cancer surgery works better than just the standard treatment. It is for people with newly diagnosed, early-stage triple-negative breast cancer.
Jinan, ShandongAges 18–70 - NCT06805812Recruiting
Predicting outcomes of CDK4/6 inhibitors plus hormone therapy for advanced breast cancer
This study looks at how well a type of targeted therapy (called CDK4/6 inhibitors) combined with hormone therapy works as the first treatment for advanced breast cancer that is hormone receptor-positive and HER2-negative. Researchers want to find patterns that could help predict which patients benefit most.
AvianoAges 18 years+ - NCT06806930RecruitingPhase 2
Predicting response to hormone therapy before breast cancer surgery
This trial tests whether we can predict how well hormone therapy works before surgery for early-stage breast cancer. It may help women with estrogen receptor-positive, HER2-negative or HER2-low breast cancer avoid or tailor treatments.
Washington D.C., District of ColumbiaAges 21 years+
Hear when a new Breast cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for breast cancer?
- Yes. Clin2 currently lists 2,478 recruiting breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.