Clinical trials
Breast cancer clinical trials
Cancer that forms in the cells of the breast, the most common cancer in women. We’re tracking 2,478 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05876390Enrolling by invitation
Regional anesthesia to reduce long-term breast surgery pain
This trial studies whether a pain-control technique called regional anesthesia during certain breast surgeries can lower chronic (long-lasting) pain after surgery. It may help improve comfort and quality of life for people at risk of ongoing pain after their breast operation.
Milan, LombardyAges 18 years+ - NCT05160480Enrolling by invitation
Total-body PET scan using FDA-approved tracers for prostate or NET cancer
This pilot study tests a total-body PET scan with approved tracer medicines to help detect cancer spread in people with suspected metastatic prostate cancer or certain neuroendocrine tumors (NETs). You may be able to join if recent scans already suggest metastasis and you can safely complete the scan timing and positioning.
Sacramento, CaliforniaAges 18 years+ - NCT06885424Enrolling by invitation
Long-term follow-up for A2 Bio gene therapy patients
This study follows up with people who previously received a gene therapy product from A2 Biotherapeutics in an earlier trial. The goal is to monitor their health over time and check for any long-term effects.
Gilbert, ArizonaAges 18 years+ - NCT03392233RecruitingPhase 2
Targeted radiation for spinal metastases causing significant pain
This trial tests a focused form of radiation (stereotactic body radiation) to treat cancer spread to the spine, especially when it causes substantial pain. It may help shrink or control the spinal spots while limiting damage to surrounding tissues.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT01173341Enrolling by invitation
Checking heart side effects of breast cancer treatments
This study looks at how breast cancer medicines affect the heart. It may help doctors better prevent, spot early, and manage heart side effects from trastuzumab and/or anthracycline chemotherapy.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05472792RecruitingPhase 2
Testing breast radiation after lumpectomy with or without hormone pills
This Phase 2 trial compares different “after-surgery” treatment plans for certain older women with hormone-sensitive early breast cancer. It looks at whether a standard hormone-pills approach or a faster, smaller-area radiation approach (given after lumpectomy) works best to prevent cancer coming back.
Chapel Hill, North CarolinaAges 65 years+ - NCT07259226RecruitingPhase 2
Studying resistance to antibody-drug conjugates in advanced cancer
This study is for people with advanced breast, bladder, lung, or stomach cancer who are about to start treatment with a type of targeted therapy called an antibody-drug conjugate (ADC). The trial will collect tumor samples and blood to understand how cancers become resistant to these drugs and to find better ways to predict treatment success.
VillejuifAges 18 years+ - NCT07447050RecruitingPhase 2
Riluzole to Prevent Chemo-Related Cognitive Problems
This pilot study tests whether the drug riluzole can help prevent the thinking and memory problems (often called 'chemobrain') that some people experience during chemotherapy. If you are about to start a chemo regimen containing an anthracycline or platinum drug, you may be able to join.
Orange, CaliforniaAges 18 years+ - NCT07592793Enrolling by invitation
Community Health Worker Perspectives on New Programs
This study asks community health center workers and partner staff about their experiences implementing a new health program. Your feedback helps researchers understand what works and what challenges exist in delivering care in community settings.
Boston, MassachusettsAges 18 years+ - NCT05556473RecruitingPhase 1
Tryptophan PET/CT scan study for different tumors
This early-phase study tests a special PET/CT scan using labeled tryptophan to help doctors see how different tumors behave. The goal is to learn whether this scan can better identify and measure cancers in the brain or elsewhere.
Detroit, MichiganAges 18 years+ - NCT06907095Recruiting
Early cancer detection study for high-risk individuals
This study tests if a simple blood or fluid test can find cancer early in people with a higher-than-average risk. If you have certain genetic mutations, a strong family history of cancer, or other high-risk conditions, you may be able to join.
VillejuifAges 18 years+ - NCT07748598Recruiting
Brain scan monitoring for HER2-positive breast cancer
This study is testing regular MRI brain scans to find any brain metastases early in people with HER2-positive breast cancer that has spread. It aims to see if early detection can help guide treatment and improve outcomes.
LiverpoolAges 16 years+ - NCT05363189Recruiting
Improving recovery after breast reconstruction with belly-tissue flap
This study looks at ways to help your recovery after breast reconstruction using tissue moved from your lower belly (a DIEP flap). You may be asked to complete a questionnaire during the recovery period.
GothenburgAges 18–100 - NCT05620329Recruiting
Pleural fluid registry for drainage in adults
This registry collects information from adults who have fluid around the lungs (pleural effusion) and need clinically indicated drainage because of infection or cancer. It helps researchers better understand these conditions and improve future care.
Chapel Hill, North CarolinaAges 18 years+ - NCT04282122Recruiting
Personalized radiation plan for older women with early breast cancer
This trial uses individual measures of how sensitive your body’s tissues are to radiation to guide after-surgery breast radiation treatment. It aims to keep treatment safe and effective while tailoring the plan to each person.
Montpellier, OccAges 65 years+ - NCT06682793RecruitingPhase 1/Phase 2
Study of A2B395 therapy for solid tumors with EGFR and HLA loss
This trial tests a new cell therapy called A2B395 for cancers that have EGFR, a protein on the cell surface, and have lost a specific marker called HLA-A*02. The therapy uses specially engineered immune cells to target and kill these cancer cells. This may help patients with colorectal, lung, head and neck, breast, kidney, or other solid tumors that are no longer responding to standard treatments.
Gilbert, ArizonaAges 18 years+ - NCT07084558Recruiting
Testing treatment guided by tumor DNA for hormone positive breast cancer
This trial tests whether using a blood test (circulating tumor DNA) can help guide chemo and hormone therapy for early-stage, hormone receptor positive and HER2 negative breast cancer. The goal is to tailor treatment to your tumor's response, potentially reducing unnecessary side effects.
Vienna, AustriaAges 18–100 - NCT06532955Recruiting
Robot-assisted surgery for arm swelling after breast cancer
This trial tests a robotic surgical technique to reconnect tiny lymph vessels and reduce arm swelling (lymphedema) in women who had breast cancer treatment. It may help if your swelling is still in the early stages.
Maastricht, LimburgAges 18 years+ - NCT06023576RecruitingPhase 2
Blood pressure control during breast cancer chemo
This study tests whether careful blood pressure management can help protect the heart during certain types of chemotherapy (anthracyclines) for breast cancer. Participants will use a smart blood pressure device and may also do an exercise test.
Basking Ridge, New JerseyAges 18 years+ - NCT07300995Recruiting
Pain coping skills for older women with breast cancer
This study tests a behavioral program to help older women with breast cancer learn skills to cope with pain. The program is done through video or phone sessions.
Durham, North CarolinaAges 55 years+ - NCT07757763Recruiting
Slow jogging for breast cancer survivors
This study looks at whether slow jogging (a gentle form of running) can help breast cancer survivors sleep better. You'll be asked to use a smartphone app to track your activity and sleep, and you may be assigned to a jogging group or a usual-care group.
Taipei, Taipei CityAges 20 years+ - NCT07729423Recruiting
Mepitel Film for skin protection during breast radiation
This trial tests if a special film placed on the skin can reduce radiation side effects in people who have had breast cancer surgery and are now getting radiation therapy.
SingaporeAges 21–100 - NCT03448926Recruiting
DCIS test registry to guide radiation and drug decisions
This study collects information from people with breast ductal carcinoma in situ (DCIS) to see how a specific lab test (DCISionRT) may help predict who benefits from radiation and/or certain medications. Your results and clinical details are gathered during routine care, not necessarily to change treatment right away.
Scottsdale, ArizonaAges 30–85 - NCT04983121RecruitingPhase 2
Neoadjuvant pyrotinib plus ARX788 for HER2-positive breast cancer
This Phase 2 trial studies whether combining pyrotinib with ARX788 given before surgery can work better and be safe in people with HER2-positive breast cancer. It’s designed for tumors that did not respond well enough to earlier trastuzumab and pertuzumab treatment.
Shenyang, LiaoningAges 18–75
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Common questions
- Are there clinical trials for breast cancer?
- Yes. Clin2 currently lists 2,478 recruiting breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.