Clinical trials
Breast clinical trials
Below are recruiting breast clinical trials, each written for real people, not researchers. We’re tracking 2,627 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07152782RecruitingPhase 2
T-DXd with or without neratinib for HER2+ breast cancer brain metastases
This trial tests whether adding neratinib to T-DXd (trastuzumab deruxtecan) works better than T-DXd alone for women with HER2-positive breast cancer that has spread to the brain. It is for those who have not had these specific drugs before.
ShanghaiAges 18–70 - NCT07150208RecruitingPhase 2
T-DXd with or without Avastin for HER2-low breast cancer that spread to the brain
This trial tests a combination of two targeted drugs (T-DXd and bevacizumab) for people with HER2-low breast cancer that has spread to the brain. It aims to see if adding bevacizumab helps the main drug work better against brain metastases.
ShanghaiAges 18–70 - NCT07135960Recruiting
Breast motion study after surgery and radiation
This study uses a 3D scanner to measure how your breast moves after surgery and possibly radiation. The results may help doctors improve treatment planning for future patients.
PortsmouthAges 18 years+ - NCT07132749Enrolling by invitation
NEPA for nausea prevention during T-DXd in advanced HER2+ or HER2-low breast cancer
This trial tests whether the anti-nausea combination NEPA (netupitant and palonosetron) can prevent nausea and vomiting caused by the targeted therapy T-DXd in people with advanced HER2-positive or HER2-low breast cancer. It may help you if you are about to start T-DXd for the first time and want to manage treatment side effects.
Seoul, Gangnam-guAges 19 years+ - NCT07131592RecruitingPhase 4
Tranexamic acid and drain fluid after breast reduction
This study tests whether giving tranexamic acid (a drug that helps blood clot) intravenously or directly into the surgical wound reduces drainage after breast reduction surgery. It may help you heal faster and avoid complications.
Boston, MassachusettsAges 18 years+ - NCT06902051Recruiting
Side-lying position for left breast cancer radiation
This trial tests whether lying on your right side during radiation therapy for left breast cancer can reduce side effects. It is for women who have had surgery for newly diagnosed left breast cancer and need radiation.
Guangzhou, Guangdong ProvinseAges 18–70 - NCT07107594Recruiting
Exercise, nutrition and support program for early breast cancer
This trial tests a program combining physical exercise, psychological support and nutritional advice before chemotherapy to see if it can improve treatment response in early breast cancer patients.
BarcelonaAges 18 years+ - NCT07102381RecruitingPhase 2
Zanidatamab plus chemo before surgery for HER2+ breast cancer
This trial tests a new drug called zanidatamab combined with chemotherapy to shrink HER2-positive breast cancer before surgery. It may help improve treatment outcomes for people with stage 2 or 3 breast cancer that has not spread.
Long Beach, CaliforniaAges 18 years+ - NCT05362760RecruitingPhase 4
Abemaciclib plus hormone therapy, with digital side-effect tracking
This trial tests whether adding abemaciclib to standard hormone (endocrine) therapy can improve outcomes for certain types of advanced breast cancer. It also uses a phone app to help you and the team track side effects so problems can be caught early.
AalenAges 18 years+ - NCT07081555RecruitingPhase 1
Testing a new radioactive drug for HER2-positive advanced breast cancer
This trial tests a new radioactive drug, [177Lu]Lu-ABY-271, to see how safe it is and where it goes in the body. It is for people with HER2-positive breast cancer that has spread and cannot be removed by surgery.
GothenburgAges 18 years+ - NCT07084519RecruitingPhase 3
Short vs standard radiation after mastectomy with implant reconstruction
This trial compares standard radiation therapy to a shorter course (hypofractionated) for women who have had a mastectomy with implant reconstruction. The goal is to see if the shorter schedule works as well while possibly reducing side effects for the reconstructed breast.
Beijing, ProvinceAges 18–75 - NCT07076147Recruiting
Breast cancer screening follow-up for moderate-risk women
This study looks at how well women with a moderate risk of breast cancer follow their screening recommendations (like yearly MRI or mammogram). It may help women who have certain genetic variants or a higher calculated risk stay on top of their breast health.
Los Angeles, CaliforniaAges 30–75 - NCT07078604RecruitingPhase 2
Vaccine with chemotherapy for advanced triple-negative breast cancer
This trial tests a cancer vaccine called STEMVAC combined with chemotherapy in people with a type of breast cancer that has spread and does not have certain markers. The goal is to see if adding the vaccine helps the chemotherapy work better.
Seattle, WashingtonAges 18 years+ - NCT07067437Recruiting
Single-dose radiation after breast cancer surgery
This trial tests a new, shorter radiation treatment given all at once after breast-conserving surgery for early-stage breast cancer. It is for people with small tumors that have not spread far, and aims to reduce side effects and visits to the clinic.
LyonAges 40 years+ - NCT07071038RecruitingPhase 2
Switching medication to relieve side effects from aromatase inhibitors
This trial tests whether switching to a different aromatase inhibitor or using standard treatments works better for managing side effects in breast cancer survivors. It aims to help you stay on hormone therapy longer with fewer discomforts.
Lebanon, New HampshireAges 18 years+ - NCT07071272Recruiting
Comparing two breast imaging methods before surgery
This trial compares a special mammogram with dye (CEDM) to MRI for women already diagnosed with invasive breast cancer. The goal is to see if CEDM works as well as MRI for planning surgery, potentially offering a faster or easier option.
Verona, ItalyAges 30 years+ - NCT06984250Recruiting
Shorter radiation with extra focus on tumor site for breast cancer
This trial tests a shorter course of radiation therapy that includes an extra dose to the tumor site for women with early-stage breast cancer. It aims to make treatment more convenient and effective after breast-conserving surgery.
Taipei, TaiwanAges 20–85 - NCT06991946Recruiting
Genomic profiling for metastatic breast cancer in Spain
This study looks at how genetic testing of your tumor might affect the treatment plan for your metastatic breast cancer. It aims to help doctors choose the best therapy based on your tumor's profile.
Barcelona, BarcelonaAges 18 years+ - NCT07047872Recruiting
3D-printed breast form study for women after mastectomy
This study tests a custom 3D-printed external breast form for people who had a mastectomy without reconstruction. It aims to see if it improves comfort and satisfaction.
Rochester, MinnesotaAges 18 years+ - NCT07053085RecruitingPhase 2
Surgery or radiation for stable HER2+ breast cancer spread
This study tests whether combining surgery or strong focused radiation with standard treatment can help people whose HER2-positive breast cancer has spread to a few spots (5 or fewer) in the body, but not the brain. It's for patients whose cancer is stable after at least 3 months of first-line therapy.
Basking Ridge, New JerseyAges 18 years+ - NCT07054723Recruiting
Surviving daily life after breast cancer
This study looks at how breast cancer survivors manage daily life. Researchers want to learn from people who are 40 or older and at least 5 years past their diagnosis. The goal is to better understand what helps people thrive after cancer.
Philadelphia, PennsylvaniaAges 40 years+ - NCT07037537Recruiting
Nipple-sparing mastectomy with immediate reconstruction (fat and implant)
This trial tests a breast cancer surgery that removes the breast but saves the nipple, followed by immediate reconstruction with an implant and some of your own fat. It's for women with early-stage cancer that hasn't spread to lymph nodes.
Zhengzhou, HenanAges 18–70 - NCT07024173RecruitingPhase 3
HRS-8080 versus doctor's choice for advanced breast cancer
This trial tests a new medicine called HRS-8080 for locally advanced or metastatic breast cancer. It compares HRS-8080 with whatever treatment your doctor would normally choose for you.
Guangzhou, GuangdongAges 18–75 - NCT07029399RecruitingPhase 1
Study of NKT5097 for advanced solid tumors
This trial tests an experimental oral drug (NKT5097) for people with advanced solid tumors that have not responded to other treatments. It may also be an option for people with a specific type of breast cancer (HR+/HER2-). The goal is to see if the drug is safe and effective.
Duarte, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for breast?
- Yes. Clin2 currently lists 2,627 recruiting breast studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.