Clinical trials
Breast clinical trials
Below are recruiting breast clinical trials, each written for real people, not researchers. We’re tracking 2,691 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05667532Recruiting
Contrast mammogram screening for women with dense breasts
This study tests how well a special mammogram with contrast can help assess breast cancer risk in women with dense breast tissue. It may help improve screening planning, especially when standard mammograms are harder to read due to density.
Houston, TexasAges 30–75 - NCT05720260RecruitingPhase 2
Test immunotherapy plus hormone therapy and an AKT blocker
This trial tests whether combining immunotherapy, hormone therapy, and an AKT-blocking drug can control ER-positive advanced breast cancer in women whose cancer is resistant to hormone treatment. It may help shrink tumors and slow disease by targeting several pathways at once.
TaipeiAges 20 years+ - NCT05732051RecruitingPhase 2
Nicotinamide riboside to protect the heart during breast cancer chemo
This trial tests whether nicotinamide riboside can help prevent heart problems caused by a common breast-cancer chemotherapy (anthracyclines). If you’re eligible, you’ll be followed to see how your heart is doing during treatment.
Lørenskog, AkershusAges 18 years+ - NCT05735080RecruitingPhase 1/Phase 2
INX-315 for advanced cancers with a specific gene change
This trial studies an experimental medicine (INX-315) given in an “open-label” way to people with advanced cancer that has not responded to prior treatment. It mainly looks at safety and side effects first, and also checks how well it works in cancers with a specific gene amplification.
Orlando, FloridaAges 18 years+ - NCT05746325Recruiting
Tumor-pulse device for spinal cancer fluid spread
This trial tests whether Tumor Treating Fields (a non-surgical device that delivers treatment signals to cancer cells through the scalp/skin) can help people whose breast or lung cancer has spread into the fluid around the spine and brain. It focuses on people who have cancer cells found in spinal fluid and can safely use the device most of the day.
Jacksonville, FloridaAges 18 years+ - NCT05760612RecruitingPhase 3
After breast cancer surgery, test neratinib plus trastuzumab
This trial studies whether adding neratinib to standard trastuzumab treatment after neoadjuvant (before-surgery) therapy lowers the risk of breast cancer coming back. It is for people whose breast cancer is hormone-receptor positive and HER2 positive, with residual cancer found after neoadjuvant treatment.
GuangzhouAges 18–70 - NCT05774951RecruitingPhase 3
Camizestrant for hormone-positive, HER2-negative early breast cancer
This trial tests camizestrant, a medicine that blocks estrogen signaling, to help prevent hormone-positive, HER2-negative early breast cancer from coming back. You may be eligible if your cancer has higher- or intermediate-risk features and you already completed at least 2 years of hormone therapy.
Birmingham, AlabamaAges 18–130 - NCT05797454Recruiting
Two ways to mark hidden breast tumors before surgery
This trial compares two techniques for pinpointing non-touchable breast cancer during breast-conserving surgery. The study aims to see which method is more accurate and whether it leads to better surgical outcomes.
Guangzhou, GuangdongAges 18 years+ - NCT05817175Recruiting
Registry for breast reconstruction using pre-pectoral implants
This trial is a registry that collects information from adults having breast reconstruction after mastectomy. It focuses on reconstruction done with pre-pectoral implants (sometimes with a tissue expander), to help doctors better understand outcomes and care over time.
Buenos AiresAges 18 years+ - NCT05838001Recruiting
Testing two ways to locate non-tumor-feel breast cancer
This trial compares two techniques for finding breast tumors that cannot be felt by hand after initial (neoadjuvant) treatment. If successful, it may make breast-conserving surgery more accurate when the tumor has become “non-palpable.”
Guangzhou, GuangdongAges 18 years+ - NCT05867251RecruitingPhase 1/Phase 2
AVZO-021 for advanced breast and ovarian cancers
This early-stage study tests AVZO-021, a new anti-cancer medicine, in people with advanced solid tumors like specific types of breast and ovarian (or related) cancers. It’s meant to find the safest dose and look for signs the medicine can shrink tumors, especially in cancers with certain gene changes.
New Haven, ConnecticutAges 18 years+ - NCT05887102Recruiting
Program to help women take hormone pills after breast cancer
This study tests a pharmacy-based program (called PACHA) designed to help women remember and stick with hormone (endocrine) treatment after breast cancer. It may help by improving support and follow-through during the first months after starting the pills.
Québec, QuebecAges 18 years+ - NCT05896865Recruiting
Personalized breast cancer radiation based on tumor biology
This trial studies whether adjusting radiation dose using how the tumor behaves can improve outcomes for people with locally advanced breast cancer that has spread to certain nearby lymph nodes. It may help deliver the right radiation intensity while avoiding unnecessary exposure.
SeoulAges 19 years+ - NCT05898009Recruiting
Study BRCA2 gene changes in breast cancer in Reunion
This study looks at how often certain BRCA2 gene changes occur in people in Réunion who have breast cancer. Your participation may help doctors understand breast cancer risk in the local community and guide future care.
Saint-PierreAges 18 years+ - NCT05907681Recruiting
Study outcomes after precise targeted radiation for metastatic breast cancer
This study follows people with breast cancer that has spread to other parts of the body who receive a highly precise form of radiation (like IMRT, SBRT, or proton therapy). It aims to see how well this treatment strategy works and what outcomes patients experience.
SeoulAges 19–100 - NCT05949541RecruitingPhase 2
Everolimus with first-line hormone therapy for specific breast cancer
This Phase 2 trial tests whether adding everolimus to standard first-line hormone (endocrine) therapy can better control a certain type of advanced breast cancer. It is designed for people whose tumor matches a specific “SNF1 subtype.”
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05954442RecruitingPhase 3
Everolimus plus chemo for advanced triple-negative breast cancer
This Phase 3 study tests whether adding everolimus to chemotherapy (chosen by the treating team) can improve outcomes in advanced triple-negative breast cancer, specifically a subtype linked to PAM pathway changes. It may help patients who have not yet had treatment for advanced/metastatic disease.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT05957068Recruiting
Exercise program for breast cancer after surgery
This study tests an exercise intervention for people with early-to-mid stage breast cancer soon after curative breast surgery (and after chemo and/or radiation if you had it). It may help improve recovery, physical strength, and overall wellbeing by making exercise safer and more structured during this period.
SingaporeAges 21–99 - NCT05959291Recruiting
Stopping long-term anti-HER2 therapy in stable metastatic breast cancer
This study asks whether some people with HER2-positive metastatic breast cancer who have been stable for a long time can safely stop their ongoing (maintenance) anti-HER2 treatment. It also uses blood testing and close imaging follow-up to watch for early signs that treatment needs to restart.
Miami, FloridaAges 18 years+ - NCT05963464Recruiting
Marker-assisted breast surgery for hard-to-feel tumors
This study tests a small implantable “marker” system (used to help doctors find the tumor or lymph node during breast surgery) for people with breast or lymph node areas that can’t be felt. It may help surgery planning and accuracy when the cancer can’t be easily located by touch.
MilanAges 18–90 - NCT05964504Recruiting
Registry study for metastatic lobular breast cancer
This study collects health information from adults with invasive lobular breast cancer that has spread (metastatic) to help researchers understand factors linked to survival. Joining may help build better knowledge for future treatments and care planning.
San Diego, CaliforniaAges 18 years+ - NCT05968157Recruiting
Breast MRI check for women at high risk
This study compares a newer breast cancer risk approach with standard guidelines, and then uses a special MRI to look for cancer early. If the MRI looks concerning, doctors will confirm the finding with a biopsy.
Worcester, MassachusettsAges 40 years+ - NCT05972343Recruiting
Cooling treatment to shrink breast tumors without surgery
This trial tests a cooling-based procedure (called cryoablation) to destroy a breast cancer tumor in people who cannot or do not want surgery. It may help shrink the visible tumor without needing an operating room.
St Louis, MissouriAges 18 years+ - NCT05976412Recruiting
Radiation to lymph nodes after surgery for higher-risk breast cancer
This trial looks at whether adding targeted radiation to lymph nodes after breast surgery can lower the chance of breast cancer coming back in people with higher-risk, node-negative disease. If you qualify, you may get a planned radiation approach designed for prevention, not treatment of spread.
Shanghai, Shanghai MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for breast?
- Yes. Clin2 currently lists 2,691 recruiting breast studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.