Clinical trials
Breast clinical trials
Below are recruiting breast clinical trials, each written for real people, not researchers. We’re tracking 2,691 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05716893RecruitingPhase 2
Aerobic exercise program for people getting breast cancer treatment
This Phase 2 study tests whether a supervised aerobic (cardio) training program can improve health and exercise capacity for people receiving treatment for primary breast cancer. You may join if you currently do very little moderate-to-vigorous exercise and can safely complete a special treadmill test that measures breathing and heart response.
Basking Ridge, New JerseyAges 18 years+ - NCT07500428Recruiting
Breast ultrasound AI study using existing images
This study uses existing breast ultrasound images to test how well artificial intelligence (AI) can interpret them. It may help improve future breast cancer detection tools.
BeijingAges 18–75 - NCT07503717Recruiting
Brain scan surveillance in HER2-positive metastatic breast cancer
This study tests whether regular brain scans (surveillance) help spot brain metastases early in people with HER2-positive breast cancer that has spread to other parts of the body. Participation involves being randomly assigned to either routine brain scans or no extra scans to see which approach is better.
BeaumontAges 18 years+ - NCT07507890Recruiting
Nipple-sparing mastectomy through one armpit incision
This trial tests a less invasive surgery for early-stage breast cancer that removes breast tissue through a single small cut in the armpit while keeping the nipple. It may be an option for women with small to medium breasts who are candidates for immediate breast reconstruction.
Candiolo, TurinAges 18 years+ - NCT07542496Recruiting
Real-world study of breast cancer treatment with pertuzumab biosimilar
This study observes how a biosimilar version of pertuzumab (a targeted breast cancer drug) works in real-world patients. Researchers will track outcomes in patients receiving this drug either before surgery or as a first treatment for advanced breast cancer.
AlgiersAges 19 years+ - NCT07546331Recruiting
Body Composition and Breast Reconstruction Outcomes
This study measures body composition (muscle and fat distribution) in patients undergoing breast reconstruction after mastectomy to understand how these measurements relate to surgical outcomes and recovery. Understanding these connections may help doctors better predict and optimize results for future patients.
San Francisco, CaliforniaAges 18 years+ - NCT07546695Recruiting
Axillary lymph node surgery choices for HER2+ and triple-negative breast cancer
This study examines the best surgical approach for removing underarm lymph nodes in patients with HER2-positive or triple-negative breast cancer who have received chemotherapy before surgery and still have cancer in their lymph nodes. The goal is to understand whether removing more lymph nodes improves outcomes for these patients.
BaselAges Any age - NCT07582887Recruiting
Genetic Testing to Predict Side Effects from Breast Cancer Antibody Drugs
This study examines how genetic differences affect how your body handles three newer breast cancer medications (Sacituzumab Govitecan, Trastuzumab Deruxtecan, or Datopotamab Deruxtecan). A blood test will check your UGT1A1 gene to help doctors predict which side effects you might experience and adjust your treatment accordingly.
Granada, GranadaAges 18 years+ - NCT07608081Recruiting
MRI imaging methods to diagnose and assess breast cancer
This study tests advanced MRI imaging techniques to better diagnose breast cancer and evaluate treatment response. If you have a suspicious breast lesion, this trial may help doctors see it more clearly before biopsy or surgery.
Kunming, YunnanAges 18–80 - NCT07610720RecruitingPhase 2
Dalpiciclib With Anti-HER2 and Hormone Therapy for Advanced Breast Cancer
This trial tests a combination of three drugs—dalpiciclib (a new cell-cycle inhibitor), anti-HER2 therapy, and hormone therapy—for advanced breast cancer that is positive for both hormone receptors and HER2 protein. The goal is to help patients whose cancer has responded to initial treatment stay in remission longer.
Guangdong, GUANGZHOUAges 18–75 - NCT07612891RecruitingPhase 1/Phase 2
Testing INV-6452 for advanced breast cancer and solid tumors
This study tests a new drug called INV-6452 to see if it is safe and can help control advanced cancers that have grown despite prior treatment. The drug targets specific cancer cell weaknesses, particularly in hormone-sensitive breast cancers without HER2 mutations.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07658170Recruiting
Fat graft with platelet-rich fibrin for breast reconstruction after lumpectomy
This trial tests using a patient's own fat plus a special blood product (platelet-rich fibrin) to rebuild the breast right after a lumpectomy for breast cancer. It may help improve healing and appearance for women with early-stage, hormone-sensitive breast cancer.
Saint PetersburgAges 18–69 - NCT07651345Enrolling by invitation
Helping Women Return for Overdue Breast Cancer Screening
This study tests different ways to encourage women in Singapore to return for mammograms (breast cancer screening) if they've fallen behind. You'd be randomly assigned to receive different types of reminders or support to help you schedule your screening.
SingaporeAges 50–69 - NCT07372261Enrolling by invitation
Predicting breast cancer spread risk
This study tests a method to predict if early-stage breast cancer might spread to other parts of the body. It uses leftover tumor tissue to help doctors plan your treatment.
San Giovanni Rotondo, FGAges 18 years+ - NCT07352137Enrolling by invitation
Endoscopic Nipple-Sparing Mastectomy with Fat Grafting for Breast Reconstruction
This trial tests a new way to remove the breast through a small cut in the armpit (endoscopic nipple-sparing mastectomy) and immediately rebuild the breast using your own fat. It's for women with early-stage breast cancer who want to keep their nipple and have reconstruction at the same time.
Guanzhou, GuangdongAges 18–70 - NCT07206888Enrolling by invitation
Study to try advanced ultrasound for breast imaging
This study explores a new way to process ultrasound images of the breast. It is for women who have a finding, cyst, mass, or calcifications seen on a mammogram or ultrasound, and it uses a special ultrasound technique that may provide clearer images without extra radiation.
Baltimore, MarylandAges 18 years+ - NCT07030231Enrolling by invitation
Intraoperative radiation therapy for breast cancer
This trial tests a type of radiation given during breast cancer surgery. It may be used alone or with standard radiation after surgery, and is also open to people whose breast cancer has come back.
Barcelona, BarcelonaAges 18 years+ - NCT06924788Enrolling by invitation
Stress management for breast cancer survivors via video
This study tests if stress management and relaxation training through video calls can help breast cancer survivors who live in under-resourced neighborhoods. It aims to improve emotional well-being and coping.
Birmingham, AlabamaAges 19 years+ - NCT06890871Enrolling by invitationPhase 1/Phase 2
Radiation with immunotherapy and anti-angiogenic therapy for advanced HER2-negative breast cancer
This trial tests a combination of radiation therapy, immunotherapy, and a drug that blocks blood vessel growth for advanced HER2-negative breast cancer that has spread. It is for patients whose cancer has worsened after at least two prior treatments.
Wuhan, HubeiAges 18–75 - NCT06768268Enrolling by invitationPhase 1/Phase 2
Better lymph node imaging for breast cancer
This trial tests whether adding two common fluids (Mannitol and Voluven) before an ICG dye injection can help surgeons better see the lymph nodes that need to be removed during breast cancer surgery. It aims to make sentinel lymph node biopsies more accurate and safer.
Hsinchu CountyAges 20–70 - NCT06671691Enrolling by invitationPhase 1
Single-dose radiation for low-risk breast cancer
This trial tests a single, high-precision dose of radiation to the tumor instead of standard surgery or multiple radiation sessions. It is for women with a small, low-risk breast cancer who cannot or choose not to have surgery.
Palma, Balearic IslandsAges Any age - NCT06650748Enrolling by invitationPhase 2
A study of hormone therapy with or without a targeted drug for breast cancer
This trial tests if adding a targeted drug (CDK4/6 inhibitor) to hormone therapy works better than hormone therapy alone for women with a certain type of breast cancer (HR+/HER2-). The study measures the activity of tumor cells (Ki-67) to help decide treatment.
BeijingAges 18–70 - NCT05975437Enrolling by invitation
Personalized follow-up care after breast cancer treatment
This trial tests whether a personalized follow-up plan after breast cancer surgery (instead of a fixed schedule) can improve care and support after treatment. It may help people know what follow-up is best for them as they move into survivorship.
Apeldoorn, GelderlandAges 40 years+ - NCT04996316Enrolling by invitation
Breast cancer screening decision help for women 40–74
This trial tests a breast cancer screening risk and decision aid to help you and your clinician choose the right next steps for screening and referrals. You may benefit by getting clearer, personalized guidance based on your risk.
Portland, OregonAges 40–74
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Common questions
- Are there clinical trials for breast?
- Yes. Clin2 currently lists 2,691 recruiting breast studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.