Clinical trials
Breast clinical trials
Below are recruiting breast clinical trials, each written for real people, not researchers. We’re tracking 2,691 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05376878RecruitingPhase 4
PET/MRI scan to guide treatment in HER2+ brain metastatic breast cancer
This trial tests a special PET/MRI imaging scan using a labeled drug to help doctors evaluate HER2+ breast cancer that has spread to the brain. It focuses on patients who plan to receive fam-trastuzumab deruxtecan, a targeted cancer medicine, and aims to see how well the scan can support treatment decisions.
Duarte, CaliforniaAges 18 years+ - NCT07350928RecruitingPhase 3
Nasal spray before breast-saving surgery for calm wakefulness
This trial tests a nasal spray (dexmedetomidine) given before breast-conserving surgery to help you stay calm and comfortable while awake during the procedure. It aims to improve your recovery and waking experience after surgery.
TianjinAges 20–70 - NCT07371585RecruitingPhase 2
Trastuzumab Deruxtecan for first-line HER2-positive advanced breast cancer
This trial tests a targeted therapy called Trastuzumab Deruxtecan (T-DXd) for people with HER2-positive breast cancer that has spread or cannot be removed. It is for those who have not yet received any chemotherapy or HER2-targeted treatment for metastatic disease. The study also focuses on managing side effects early, using digital tools to track symptoms.
VillejuifAges 18 years+ - NCT07373782RecruitingPhase 2/Phase 3
CPAP mask during radiation for breast cancer
This trial tests whether using a CPAP mask during daily radiation treatments for breast cancer can help protect your heart. It is for women who had a lumpectomy and need radiation to the left breast or to the right breast with lymph nodes.
LeuvenAges 40–80 - NCT07383818RecruitingPhase 2
Neoadjuvant therapy with trastuzumab rezetecan and toripalimab for HR+/HER2-low breast cancer
This trial tests a combination of two drugs (trastuzumab rezetecan and toripalimab) given before surgery to treat a specific type of breast cancer that is hormone-receptor-positive and HER2-low. It aims to see if this treatment can improve outcomes for patients who have not had prior cancer treatment.
HarbinAges 18–70 - NCT07389408Recruiting
Early breast cancer treatment patterns study
This study observes how doctors treat early breast cancer and what outcomes patients have. It's for people with hormone receptor-positive, HER2-negative breast cancer that hasn't spread to many lymph nodes.
AthensAges 18 years+ - NCT07389967Recruiting
Nutrition awareness study for women after breast cancer treatment
This study looks at how aware women are about nutrition after finishing their main breast cancer treatment. It aims to help improve support for diet and healthy eating habits.
Chapel Hill, North CarolinaAges 18 years+ - NCT00477100Recruiting
Breast cancer tissue and data registry for research
This trial helps create a research “tissue registry” by collecting breast cancer tissue samples and medical information. It may help doctors better understand inflammatory or invasive breast cancer and improve future studies.
Gilbert, ArizonaAges 18 years+ - NCT01503190Recruiting
Study of how breast cancer affects the immune system
This study looks at how the immune system changes in people with breast cancer, using patient tissue samples. It may help researchers understand immune responses in young women and guide future cancer treatments.
Aurora, ColoradoAges 18 years+ - NCT01785420RecruitingPhase 3
Trastuzumab before breast surgery for HER2-positive cancer
This trial tests whether giving trastuzumab before surgery can improve outcomes for people with HER2-positive early breast cancer. Trastuzumab is a targeted medicine that helps treat HER2-driven cancer before the tumor is removed.
MumbaiAges 18–80 - NCT00291096Recruiting
Clinic program for women at high risk of breast cancer
This trial enrolls women who are at higher-than-usual risk of developing breast cancer to help guide prevention and monitoring. You may be asked to get a recent mammogram, have blood tests, and follow medication/supplement changes.
Kansas City, KansasAges 30–65 - NCT00353483Recruiting
Testing treatment before or after breast cancer surgery
This trial studies how different cancer treatments given before or after standard therapy affect breast cancer cells in the blood and bone marrow. It may help doctors better understand how treatments work throughout the body, not just where the tumor is.
St Louis, MissouriAges 18 years+ - NCT01840293Recruiting
Breast cancer study using tumor tissue to find key differences
This trial looks at breast cancer “proteins” and molecular features using tumor samples taken during surgery or biopsy. The goal is to better understand why breast cancers behave differently, which may help guide more personalized treatment in the future.
CorkAges 18 years+ - NCT02620852Recruiting
Wisdom Study: Women’s breast cancer screening decisions
This study looks at how to decide the best breast cancer screening (like mammograms) based on your personal risk. It may help by testing a smarter way to match screening to your risk level.
Birmingham, AlabamaAges 30–74 - NCT02819882Recruiting
Registry study for advanced or metastatic breast cancer
This study collects health and treatment information from people with breast cancer that cannot be fully removed by surgery or that has spread to other parts of the body. It may help researchers better understand which treatments are used and how people do over time.
Elche, AlicanteAges 18 years+ - NCT02977468RecruitingPhase 1
Pembrolizumab for early triple-negative breast cancer tumor changes
This Phase 1 study tests pembrolizumab (an immune medicine) to see how it affects the tumor and its surroundings in triple-negative breast cancer. It’s mainly looking at safety and early signs of benefit, especially in a limited, early-stage breast tumor.
Atlanta, GeorgiaAges 21–80 - NCT07401537RecruitingPhase 2
Comparing two schedules of immunotherapy for advanced triple-negative breast cancer
This trial tests whether giving immunotherapy less often (extended dose intervals) works as well as the standard schedule for people with advanced triple-negative breast cancer who have already completed 6 cycles of first-line treatment. It aims to see if a longer break between doses can be just as effective with fewer hospital visits.
Guangzhou, GuangdongAges 18–70 - NCT07407153Recruiting
Using portable ultrasound to check breast lumps
This trial tests if a portable ultrasound device can help quickly evaluate breast lumps found during a physical exam. It aims to improve screening in places where standard mammography may not be available.
Jakarta, West JakartaAges 30–69 - NCT07426913Recruiting
Virtual reality heart health for breast cancer survivors
This trial tests if a virtual reality program can help breast cancer survivors taking certain chemotherapies improve their heart health. It's for people currently receiving trastuzumab or anthracycline-based treatment, along with immunotherapy, for their first breast cancer diagnosis.
Richmond, VirginiaAges 18 years+ - NCT07443579Recruiting
Mammogram order study for breast cancer survivors
This trial tests if changing the order of mammogram views makes the exam more comfortable for women who have had breast cancer surgery and radiation. You may be able to join if you are due for your first check-up mammogram after finishing treatment.
Beaumont, DublinAges 18 years+ - NCT07448246Recruiting
Rhomboid block for pain after breast implant surgery
This trial tests if a specific nerve block (rhomboid intercostal block) can reduce pain after breast implant surgery. If you are having bilateral breast implants and are in good general health, you may be eligible.
Aydin, EfelerAges 18–65 - NCT07467824Recruiting
Exercise and support before and after breast cancer treatment
This trial tests whether a program of supervised exercise and full follow-up before and after breast cancer treatment can improve recovery and quality of life for women with early-stage breast cancer.
Valladolid, ValladolidAges 18–65 - NCT07478900Recruiting
Tattoo marking breast tumors before chemo
This trial tests a simple method: marking the tumor with a small tattoo before chemotherapy. The tattoo helps surgeons find the exact spot for lumpectomy after the tumor shrinks, so you can keep more of your breast.
Bhubaneswar, OdishaAges 18–75 - NCT07484087Recruiting
Ablation vs. Surgery for Early Breast Cancer
This trial compares a less invasive treatment called ablation (which uses extreme cold to destroy the tumor) with standard surgery for early-stage breast cancer. It is for women aged 50 or older with a small, low-risk tumor that has not spread.
Beijing, Beijing MunicipalityAges 50 years+
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Common questions
- Are there clinical trials for breast?
- Yes. Clin2 currently lists 2,691 recruiting breast studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.