Clinical trials
Bupivacaine clinical trials
Below are recruiting bupivacaine clinical trials, each written for real people, not researchers. We’re tracking 202 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04908579RecruitingPhase 4
Preventive ketamine to reduce pain after surgery
This study tests whether giving ketamine before or during surgery can reduce pain afterward. It is designed for adults with higher body weight who also have certain health conditions like well-controlled diabetes or blood pressure.
CairoAges 21–60 - NCT03737292RecruitingPhase 4
Numbing medicine for chest surgery pain after small lung operations
This trial tests whether a long-lasting numbing shot (liposomal bupivacaine) works better than a regular numbing shot (plain bupivacaine) for pain after minimally invasive chest surgery. It may help you have less post-surgery pain and potentially use less pain medication.
Hershey, PennsylvaniaAges 18 years+ - NCT03906617RecruitingPhase 4
Pain-relief shots for lung surgery: three drug options compared
This study compares different pain-relief medications given during lung surgery to see which one controls pain better. It may help people have less post-surgery pain after robotic wedge resection or lobectomy.
Camden, New JerseyAges 18–90 - NCT07779551Enrolling by invitation
Pain relief after thyroid surgery: comparing two numbing drugs
This study compares two medications, bupivacaine and ropivacaine, given as a neck block before thyroid surgery to see which provides better pain relief after the operation. It may help reduce post-surgery discomfort.
Sargodha, Punjab ProvinceAges 20–40 - NCT07770932Recruiting
Pain relief after hip replacement surgery
This study compares two types of nerve blocks for pain relief after hip replacement surgery. It aims to find which method reduces pain and improves recovery.
Istanbul, BagcilarAges 18–80 - NCT07775248RecruitingPhase 4
Long-lasting pain relief after knee replacement
This trial tests a new type of pain medicine that is given during knee replacement surgery and slowly releases pain relief over several days. It may help reduce the need for opioid painkillers after surgery.
Grosse Pointe Farms, MichiganAges 18 years+ - NCT05824338RecruitingEarly Phase 1
Testing ropivacaine spinal anesthesia for lower back surgery
This early study tests whether using ropivacaine (a local numbing medicine) in spinal anesthesia is safe and workable for certain lower back operations. If you qualify, it may help doctors refine anesthesia choices for your type of surgery.
New Westminster, British ColumbiaAges 19–80 - NCT06633068RecruitingPhase 2
Pain relief study: nalbuphine added to numbing medicine for thyroid surgery
This study tests if adding nalbuphine to the numbing medicine (bupivacaine) given as a nerve block before thyroid surgery provides better pain relief. It is for adults having planned thyroid surgery.
Giza, الجيزةAges 18–60 - NCT07650760RecruitingPhase 4
Pain Relief After Gallbladder Removal Surgery
This trial tests whether flushing the abdomen with a numbing medication (bupivacaine) during minimally invasive gallbladder surgery reduces pain after the procedure compared to using saline (salt water) alone.
Wāh, Punjab ProvinceAges 18–60 - NCT07651722Recruiting
Pain control and gut recovery after abdominal surgery
This trial tests a combination of two pain-management approaches—a long-acting numbing medicine injected near nerves and a self-administered opioid—to see if they help your gut function better and control pain after bowel or colon surgery.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT07632820RecruitingPhase 4
Nerve Block vs. Injection for Upper Back Muscle Pain
This study compares two ways to treat chronic muscle pain in the upper back: a nerve block (numbing injection near the spine) and trigger point injections (shots directly into painful muscle knots). The goal is to see which approach works better for long-lasting relief.
Jacksonville, FloridaAges 18–80 - NCT07584915Enrolling by invitationPhase 4
Pain Relief Method Comparison for Knee Replacement Surgery
This study tests a new way to deliver pain medication during and after knee replacement surgery. Researchers compare injecting a long-acting numbing medicine (EXPAREL) directly into the knee joint versus spreading it through the surgical area, to see which method works better for pain control.
Los Angeles, CaliforniaAges 18 years+ - NCT07574385RecruitingPhase 2
Nerve Block Pain Relief After Bunion Surgery
This study tests a new nerve-blocking medication (ALX006) injected near the sciatic nerve to reduce pain after bunion surgery. The goal is to see if it provides better pain relief compared to standard care.
Millcreek, UtahAges 18 years+ - NCT07522736Recruiting
Spinal anesthesia with dexmedetomidine for knee surgery
This trial tests adding dexmedetomidine (a calming medication) to bupivacaine (numbing medication) injected into the spine during knee surgery. The goal is to improve pain relief and recovery after surgery.
CairoAges 18–65 - NCT07513012Enrolling by invitation
Pain Relief Methods After Gallbladder Removal Surgery
This study compares two ways of numbing the abdomen during gallbladder removal surgery to see which one works better for pain relief. One method numbs one side of your belly, and the other numbs both sides.
Lahore, Punjab ProvinceAges 18–80 - NCT07506044Recruiting
Dexmedetomidine in epidural for labor pain relief
This trial tests adding dexmedetomidine to the epidural medicine used for pain relief during labor. If you are in early labor with a healthy pregnancy, this could help manage pain more effectively.
Shebeen El KomAges 18–40 - NCT07496632Recruiting
Scalp Numbing for Brain Surgery: Pain and Stability Study
This trial tests whether a numbing injection around the scalp (called a scalp block) can help keep your blood pressure and heart rate stable during brain surgery and reduce pain after surgery. It is for people having a planned craniotomy (surgery that opens the skull) on the upper part of the brain.
DhakaAges 18–64 - NCT07482709RecruitingPhase 1/Phase 2
Nerve block with or without ketamine for hysterectomy pain
This study compares two ways to reduce pain after a hysterectomy: a standard nerve block with bupivacaine (a numbing medicine) versus the same block plus ketamine (a medicine that can boost pain relief). The goal is to see if adding ketamine provides better comfort after surgery.
Karachi, SindhAges 25–65 - NCT07450781Enrolling by invitation
How saline temperature and local anesthetics affect shoulder pain after gallbladder surgery
This trial tests whether warming the saline used during surgery or adding a numbing medicine can reduce shoulder pain after laparoscopic gallbladder removal. It also checks how these affect inflammation markers in the blood.
AlexandriaAges 18–65 - NCT07435909Recruiting
Bupivacaine for pain after laparoscopic hysterectomy
This trial tests if injecting a numbing medicine called bupivacaine into the abdomen during surgery can reduce pain after a laparoscopic hysterectomy (uterus removal through small cuts). It may help you recover with less discomfort.
Istanbul, GaziosmanpaşaAges 35–75 - NCT07429448RecruitingPhase 1
Numbing medicine for pain after appendix removal
This trial tests whether numbing medicine (bupivacaine) placed into the belly during an open appendix removal helps reduce pain after surgery, compared to a placebo (a shot with no medicine).
Lahore, Punjab ProvinceAges 20–60 - NCT07400146RecruitingPhase 4
Numbing medicine for pain relief in laparoscopic surgery
This trial tests if numbing medicine (bupivacaine with epinephrine) placed over the diaphragm during laparoscopic surgery can reduce shoulder and other pain. It may help patients undergoing gynecologic laparoscopy recover more comfortably.
Los Angeles, CaliforniaAges 18 years+ - NCT07386327Recruiting
Comparing diluted bupivacaine for arm surgery nerve block
This trial tests whether mixing the numbing medicine bupivacaine with sugar water (dextrose) or salt water (saline) affects how well a nerve block works for upper arm surgery. The goal is to find which mixture provides better pain relief with fewer side effects.
SakaryaAges 18–65 - NCT07349810RecruitingPhase 4
Post-surgery pain pump study
This trial tests a pain pump after specific shoulder or knee surgeries to see how well it controls pain. It may help you recover more comfortably after surgery.
Somerset, New JerseyAges 18 years+
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Common questions
- Are there clinical trials for bupivacaine?
- Yes. Clin2 currently lists 202 recruiting bupivacaine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bupivacaine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bupivacaine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.