Clinical trials
Cancer Risk clinical trials
Below are recruiting cancer risk clinical trials, each written for real people, not researchers. We’re tracking 721 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04344496Recruiting
Collecting breast cancer tissue to predict recurrence risk
This study builds a “genome atlas” to better predict the chance that breast cancer will come back. It asks participants to share medical information and provide blood and tumor tissue samples, including samples kept in paraffin.
TaipeiAges 20 years+ - NCT06584279Recruiting
MRI-targeted biopsy for first-time prostate cancer screening
This trial is testing a new way to do prostate biopsies by combining MRI findings with a targeted biopsy on the same side as the suspicious area. It is for men who have not had a biopsy before and have a moderately high PSA level.
NanjingAges 60–80 - NCT07669298Recruiting
Monitoring vs chemoradiation for early rectal cancer
This study compares two approaches after early-stage rectal cancer is removed: either careful monitoring or a follow-up treatment with chemotherapy and radiation. The goal is to see which strategy works better to keep the cancer from returning.
LimogesAges 18 years+ - NCT07349069RecruitingPhase 3
HRS-8080 vs. standard hormone therapy for early breast cancer
This trial tests a new oral drug (HRS-8080) against standard hormone therapy for women with intermediate- or high-risk early breast cancer who have already completed 2 to 5 years of hormone treatment. It aims to see if the new drug can reduce the risk of cancer coming back.
Nanjing, JiangsuAges 18–75 - NCT07222436Recruiting
Blood test for high-risk prostate cancer
This trial studies a blood test that looks for tumor DNA in men with high-risk or advanced prostate cancer. It may help doctors understand the cancer better and guide treatment decisions.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07148154Recruiting
Non-invasive test for endometrial cancer screening
This study tests a simple, non-invasive method to detect endometrial cancer in women after menopause who have abnormal bleeding. It aims to find cancer early in those at higher risk, such as women with certain genetic conditions or risk factors.
L'Hospitalet de Llobregat, BarcelonaAges 40 years+ - NCT06997185Recruiting
Study on explaining cancer drug benefits and risks
This study looks at how to explain the benefits and risks of new cancer drugs in a way that is easier to understand. It helps researchers learn how to communicate better with patients like you.
Boston, MassachusettsAges 18 years+ - NCT06554158Recruiting
Lowering radiation for low-risk HPV throat cancer patients
This trial tests whether giving less radiation after surgery is safe and effective for people with early-stage HPV-related throat cancer. It aims to reduce side effects while still controlling the cancer.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06364267RecruitingPhase 2
Low dose exemestane vs low dose tamoxifen for breast cancer prevention
This trial compares two low-dose medications, exemestane and tamoxifen, to see which is better at preventing breast cancer in postmenopausal women who have a higher risk. You would take one of these pills daily for a few years, and the study will check how well it works and what side effects occur.
Genova, ItalyAges Any age - NCT06300125Recruiting
Freezing small low-risk breast tumors without surgery
This trial tests cryoablation (freezing the tumor with a needle) as a way to treat small, low-risk breast cancers without surgery. It is for women 50 or older whose cancers are hormone-receptor-positive and haven't spread to lymph nodes.
MilanAges 50 years+ - NCT06151223Recruiting
Pancreatic cancer risk registry for high-risk individuals
This study is a registry for people at high risk for pancreatic cancer. Researchers will collect information over time to learn more about how to detect and prevent the disease.
Rochester, MinnesotaAges 18 years+ - NCT04550845Recruiting
Study to teach genetics to men at risk for prostate cancer
This study aims to understand how men at higher risk for prostate cancer understand genetics terms, using an educational video. It may help improve patient education about genetic testing, especially for people who find these terms confusing.
Phoenix, ArizonaAges 40–95 - NCT05726292RecruitingPhase 2
Enzalutamide plus relacorilant versus placebo for high-risk prostate cancer
This study tests whether adding relacorilant to enzalutamide (a hormone-blocking treatment) helps control high-risk localized prostate cancer better than enzalutamide plus a dummy pill. It may help prevent the cancer from growing or spreading by targeting a hormone pathway in addition to standard treatment.
Chicago, IllinoisAges 18 years+ - NCT04812366RecruitingPhase 2
Genetic test-guided treatment before prostate surgery
This trial tests different drugs before prostate surgery based on a person's genetic profile. It aims to find better treatments for high-risk prostate cancer that hasn't spread yet.
Sacramento, CaliforniaAges 18 years+ - NCT04517266Recruiting
Testing less radiation to the inner breast area
This trial studies whether some patients with early-stage breast cancer can safely skip a specific part of radiation to the inner chest (called internal mammary irradiation). It may reduce radiation side effects while still aiming to prevent the cancer from coming back.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT03729115Recruiting
Enhanced breast cancer screening for high-risk women
This study tests a more thorough breast cancer screening program using MRI and other imaging for women at high risk. It aims to detect cancer earlier, which may improve treatment options and outcomes.
La Jolla, CaliforniaAges 25 years+ - NCT06816121Recruiting
Blood test for early lung cancer in high-risk smokers
This study is evaluating a blood-based test that might detect lung cancer early, before symptoms appear. Researchers are looking for heavy smokers who have no signs of cancer, as well as those with suspicious lung nodules or confirmed lung cancer, to see if a simple blood draw could help identify cancer sooner.
Oklahoma City, OklahomaAges 30–80 - NCT04743479Recruiting
AI screening for pancreatic cancer in higher-risk people
This trial uses an artificial-intelligence tool to help detect pancreatic cancer earlier and track people at higher risk. You may be asked to complete questionnaires and have imaging tests like MRI or CT to see how well the approach works.
ShanghaiAges 50–75 - NCT07281599Recruiting
Using a pad to screen for cervical precancer
This trial tests whether a special pad you wear during your period can detect signs of cervical precancer. If you are already scheduled for a colposcopy due to an abnormal Pap or HPV test, you might be able to participate.
New Haven, ConnecticutAges 25 years+ - NCT07216144Enrolling by invitation
Lung cancer screening outreach in at-risk New Yorkers
This study helps patients at Ryan Health who are at risk for lung cancer get a free lung cancer screening (a low-dose CT scan). If you're between 50 and 80, smoke or used to smoke, and haven't had this scan in the past year, you may be able to participate.
New York, New YorkAges 50–80 - NCT07532434Recruiting
Risk-Reducing Surgery for Hereditary Ovarian Cancer
This study follows women who carry gene mutations that increase ovarian cancer risk to understand how preventive surgery affects their health, quality of life, and peace of mind. Researchers will track your outcomes over 3 years to help inform future treatment decisions for others at similar risk.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05931419Recruiting
Radiation versus surgery for high-risk prostate cancer
This trial compares two standard treatment options—radiation or surgery—for people with high-risk prostate cancer that has not spread. The goal is to see which approach works better for long-term cancer control and side effects.
AlkmaarAges 50–75 - NCT06823414Recruiting
Robotic-assisted nipple-sparing mastectomy trial
This trial tests a robotic-assisted surgery technique for women who need a mastectomy but can keep their skin and nipple. It aims to improve outcomes for breast cancer patients and those at high risk.
A Coruña, GaliciaAges 18 years+ - NCT05443412Recruiting
AI tool to help detect prostate cancer from MRI and biopsy results
This study tests an artificial intelligence (AI) tool that may improve how doctors detect prostate cancer using imaging and biopsy information. It could help better identify cancer that is suspected based on PSA blood tests and rectal exam findings.
Hong KongAges 18 years+
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Common questions
- Are there clinical trials for cancer risk?
- Yes. Clin2 currently lists 721 recruiting cancer risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.