Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,086 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06568705RecruitingPhase 2
Shorter adaptive radiation for early breast cancer
This trial tests a shorter, more targeted course of daily radiation for early-stage breast cancer. The radiation plan is adjusted each day to better fit your body, which may reduce side effects.
BeijingAges 35–70 - NCT07645378Recruiting
Comparing one vs two heat treatments for cervical precancer
This study tests whether using one or two heat probes is better at removing precancerous cells from the cervix in women living with HIV. It aims to find a simpler, more effective way to prevent cervical cancer.
DurbanAges 25–49 - NCT07213674RecruitingPhase 3
A study of xaluritamig plus abiraterone for prostate cancer
This trial tests a new combination of two drugs (xaluritamig plus abiraterone) for men with a type of advanced prostate cancer that is no longer responding to hormone therapy but has not yet been treated with chemotherapy. The goal is to see if this combination works better than the standard options your doctor might choose.
Goodyear, ArizonaAges 18 years+ - NCT06508567Recruiting
MRI-Guided Internal Radiation for Returning Prostate Cancer
This trial tests a new way to use a type of internal radiation (high-dose-rate brachytherapy) guided by MRI to treat prostate cancer that has come back in the same area after previous radiation therapy. It is designed to be more precise and hopefully safer while using the latest PSMA PET scans to make sure the cancer hasn't spread.
Toronto, OntarioAges 18 years+ - NCT07881341Recruiting
Radiation treatment for left breast cancer
This study looks at how radiation treatment for left-sided breast cancer affects the surrounding tissues. It aims to better understand the impact so doctors can plan treatment more safely.
Meldola, FCAges 18 years+ - NCT07879820Recruiting
PSMA-guided surgery for prostate cancer that has spread to lymph nodes
This trial tests whether using a special imaging tracer during surgery helps find and remove prostate cancer that has spread to lymph nodes, and whether studying immune cells in the removed tissue can predict how well the treatment works.
Milan, LombardyAges 18–85 - NCT07881133Recruiting
Biomarker Study in Colorectal and Gastric Cancer Surgery
This study looks at blood markers before and after surgery for colorectal or stomach cancer. The goal is to understand how these markers change and what they might tell us about recovery.
Bucharest, BucharestAges 18 years+ - NCT07062965RecruitingPhase 3
PF-07248144 with fulvestrant for HR+ HER2- advanced breast cancer
This trial tests a new study medicine (PF-07248144) combined with fulvestrant in people with a certain type of advanced breast cancer (HR-positive, HER2-negative) that has worsened after previous treatments. It may be an option if you've already tried a CDK4/6 inhibitor and endocrine therapy.
Anchorage, AlaskaAges 18 years+ - NCT07741565RecruitingEarly Phase 1
Nivolumab before surgery for head and neck cancer
This study tests a specially marked version of a drug called nivolumab (an immunotherapy that helps your immune system fight cancer) given directly into the tumor before your scheduled surgery. The goal is to help researchers see how the drug works in the tumor and whether it could improve treatment for head and neck cancer.
Nashville, TennesseeAges 18 years+ - NCT07619599RecruitingPhase 1
PET Scan to Track Lung Cancer Treatment Response
This study uses a special PET imaging scan to help doctors see how well pembrolizumab (an immunotherapy drug) is working against advanced non-small cell lung cancer. You'll receive the scan along with your regular pembrolizumab treatment and possible radiation therapy to help measure treatment response.
Duarte, CaliforniaAges 18 years+ - NCT07698535RecruitingPhase 2
Blood test to guide early stopping of prostate cancer therapy
This trial uses a blood test to measure tumor DNA and see if men with advanced prostate cancer can safely stop treatment with a drug called 177Lu-PSMA-617 earlier than usual, or switch to chemotherapy. It may help reduce side effects while still controlling the cancer.
Seattle, WashingtonAges 18 years+ - NCT06820463RecruitingPhase 2
Study of telisotuzumab adizutecan plus chemo for metastatic colorectal cancer
This trial tests a new drug combination for people with metastatic colorectal cancer. The study includes an experimental antibody-drug conjugate (telisotuzumab adizutecan) plus standard chemotherapy and targeted therapies, to see if it works better than current options.
Duarte, CaliforniaAges 18 years+ - NCT07237269RecruitingPhase 2
Abiraterone/prednisone plus ADT for early prostate cancer
This trial tests adding abiraterone (a hormone therapy pill) and prednisone to standard hormone therapy (ADT) for prostate cancer that has spread to nearby lymph nodes but is too small to see on regular scans. The goal is to see if this combination works better than ADT alone.
Omaha, NebraskaAges 30 years+ - NCT07566156RecruitingPhase 3
New drug combination vs. radiation for bladder cancer preservation
This trial tests whether two drugs (enfortumab vedotin and pembrolizumab) work better than radiation with chemotherapy for muscle-invasive bladder cancer. The goal is to treat your cancer while keeping your bladder instead of removing it.
Little Rock, ArkansasAges 18 years+ - NCT05673018Recruiting
Galleri blood test study in Medicare patients
This study looks at how a blood test called Galleri (and also how it compares when people have not yet had it) works for older adults with Medicare. It may help find whether the test can improve cancer detection or follow-up for people who are not already in urgent cancer workups.
Fort Smith, ArkansasAges 50 years+ - NCT07293247RecruitingPhase 2
Targeted radiation after lung cancer surgery
This trial tests if targeted radiation after surgery can help people with non-small cell lung cancer who still have cancer in their lymph nodes after chemotherapy. Participants will have had surgery and chemotherapy before starting radiation.
Jonesboro, ArkansasAges 18 years+ - NCT07773987RecruitingPhase 2
Immunotherapy and targeted radiation for head and neck cancer
This trial combines immunotherapy with a special type of radiation that spares healthy lymph nodes, aiming to boost the body's immune response against the tumor. It is for patients with certain types of head and neck cancer that have not spread too far and can be surgically removed.
Milwaukee, WisconsinAges 18 years+ - NCT07645352Recruiting
One or two probes for cervical heat treatment in women with HIV
This study compares using one versus two probes during a heat treatment (thermal ablation) for early cervical changes in women living with HIV. The goal is to see which approach is more feasible and effective, hopefully preventing cervical cancer.
HarareAges 25–49 - NCT07715747RecruitingPhase 1
TJ037130 for advanced solid tumors
This trial tests an investigational drug called TJ037130 in people with advanced solid tumors that have not responded to standard treatments or for whom no standard treatment is available. The drug targets a protein called Claudin 6 on tumor cells and may help your immune system fight the cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07198074RecruitingPhase 3
Testing Avastin added to chemo plus Keytruda for certain endometrial cancer
This study tests adding Avastin (bevacizumab) to the standard combination of chemotherapy (carboplatin and paclitaxel) plus immunotherapy (Keytruda) for advanced or recurrent endometrial cancer with a specific genetic makeup (pMMR and TP53 mutation). The goal is to see if adding Avastin helps shrink tumors or slow their growth.
Birmingham, AlabamaAges 18 years+ - NCT06791057Recruiting
Breathing help for advanced lung cancer
This study tests a short program to help people with advanced lung cancer or mesothelioma feel less short of breath. It may teach you simple techniques to manage breathlessness and improve your daily life.
Coral Gables, FloridaAges 18 years+ - NCT07390916Recruiting
Cervical precancer treatment study for women with HIV
This study tests whether using one or two heat probes works better to remove cervical precancer in women with HIV. Participants will get treatment at a clinic in Rwanda and be checked again after 6 months.
KigaliAges 25–49 - NCT07611110RecruitingPhase 3
AZD2265 vs standard care for advanced prostate cancer
This trial tests a new cancer-fighting drug called AZD2265 against standard treatment for men with advanced prostate cancer that has spread and stopped responding to hormone therapy. You may qualify if your cancer previously responded to PSMA-targeted radiation treatments but is now growing again.
Dothan, AlabamaAges 18 years+ - NCT07419295RecruitingPhase 3
Testing a new drug for advanced bladder cancer
This trial is for people with advanced bladder cancer (urothelial cancer) that has spread or can't be removed. It tests a new drug called sacituzumab tirumotecan against standard chemotherapy options to see if it works better.
Washington D.C., District of ColumbiaAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,086 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.