Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,324 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05674357Recruiting
Training therapists to help people with cancer distress
This trial trains therapists in evidence-based treatments to reduce distress related to cancer and cancer care. You may be able to join if you’re being treated or followed at MGH Cancer Center and your distress level is high.
Boston, MassachusettsAges 18 years+ - NCT05674825RecruitingPhase 1/Phase 2
Personalized treatment using tumor test results for aggressive cancers
This early-phase study tests whether a personalized cancer treatment plan based on your tumor’s test results can help people with aggressive cancers that are hard to treat. It may be an option if standard treatments didn’t work, aren’t possible for you, or you have few treatment choices.
Milwaukee, WisconsinAges 18 years+ - NCT05676190Recruiting
Cell therapy using your own immune cells for colorectal cancer
This trial studies an immune cell treatment made from your own blood cells to treat colorectal cancer that has spread or progressed. You may be eligible if you have stage III–IV disease that can be measured on scans and if standard treatments have not worked or couldn’t be tolerated.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT05677022Recruiting
Posture and movement check during adapted exercise after breast cancer
This study looks at how a posture and movement assessment can help guide a tailored exercise program for people treated for non-metastatic breast cancer. It may help ensure the exercise is safer and more suited to your recovery needs.
MarseilleAges 18 years+ - NCT05679583RecruitingPhase 2
Pre-surgery focused radiation for resectable pancreatic cancer
This trial studies giving highly targeted radiation before surgery for patients with operable pancreatic cancer. The goal is to shrink or control the cancer before an operation while keeping side effects manageable.
SeoulAges 20 years+ - NCT05679674Recruiting
Radiation plus at-home tumor device for locally advanced pancreatic cancer
This trial tests whether combining targeted radiation with an at-home “tumor treating fields” device can better control locally advanced pancreatic cancer. It may help by attacking cancer cells in more than one way after prior chemotherapy.
Miami, FloridaAges 18 years+ - NCT05681195RecruitingPhase 2
Zanubrutinib plus pemetrexed for recurrent brain lymphomas
This trial tests zanubrutinib (a targeted lymphoma medicine) together with pemetrexed (chemotherapy) for lymphoma that has come back or did not respond well in or around the brain. It may help shrink measurable lymphoma and improve control of disease after prior treatments.
Miami, FloridaAges 18 years+ - NCT05683418RecruitingPhase 1
Study of a new drug for PIK3CA-mutated HR+ HER2- breast cancer
This early-stage study tests the safety and tolerability of TOS-358 in women with HR-positive, HER2-negative breast cancer that has a specific gene change (PIK3CA). It may help learn whether this targeted treatment is safe enough to move forward.
Chicago, IllinoisAges 18 years+ - NCT05684731RecruitingPhase 1
Test drug KM1 for repeat or resistant ovarian cancer
This early-phase study tests whether KM1 is safe and can shrink or control ovarian, fallopian tube, or primary peritoneal cancer that has come back or not responded to standard treatment. It may help people who have limited options, but eligibility is strict to keep participants safe.
Wuhan, HubeiAges 18 years+ - NCT05684367Recruiting
Exercise program to rebuild stamina and energy after breast cancer
This study tests whether a structured exercise program can help older adults with breast cancer regain stamina and reduce fatigue. It focuses on people who are still dealing with moderate fatigue after finishing certain breast cancer treatments.
Gainesville, FloridaAges 60–105 - NCT05686499Recruiting
Colonoscopy training for early colorectal cancer detection
This trial supports training for healthcare professionals to improve screening and early diagnosis of colorectal cancer. It may help by building skills in safely performing colonoscopies and spotting cancer earlier.
Ile-Ife, Osun StateAges 18 years+ - NCT05687357RecruitingPhase 2
Tislelizumab plus chemoradiation before surgery for stomach cancer
This Phase 2 trial studies giving tislelizumab (an immune therapy) together with pre-surgery chemoradiation for locally advanced stomach or GEJ (esophagus-stomach junction) adenocarcinoma. It compares this approach to the standard treatment (chemoradiation plus surgery) to see if it improves outcomes.
Wuhan, HubeiAges 18–75 - NCT05687188Recruiting
Study obesity links to pancreatic cancer in specific groups
This study looks at how weight and related body changes may lead to pancreatic tumors, focusing on people who are African American or Non-Hispanic White. It may help researchers better understand why pancreatic cancer risk differs between groups.
Tampa, FloridaAges 18 years+ - NCT05687604Recruiting
Telehealth program to reduce cancer risk behaviors
This trial offers a scalable telehealth (phone/video) program to help people improve cancer risk habits like low physical activity, higher body weight, and smoking. It may help by giving structured coaching and support in the privacy of your home.
Chicago, IllinoisAges 18 years+ - NCT05692024RecruitingPhase 1/Phase 2
Coffee and gut bacteria study after colon or rectal cancer
This early-phase study tests whether a coffee-related approach can change gut bacteria and blood “metabolites” after treatment for stage I–III colon or rectal cancer. The goal is to learn if these changes could help improve health after standard cancer treatment.
Boston, MassachusettsAges 18 years+ - NCT05692674RecruitingPhase 2
Proton radiation after breast surgery with implant reconstruction
This trial studies a type of radiation made with proton beams given after mastectomy and implant reconstruction to lower breast cancer coming back. It’s for people who need additional (adjuvant) radiation and have not had prior radiation to the chest or breast.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05694338Recruiting
Study frailty during major surgery for gut cancer
This trial studies how “frailty” affects people with gastrointestinal (gut) cancer who are about to have major surgery, sometimes after chemotherapy or other treatment beforehand. It may help doctors better prepare and support patients through surgery.
East Corning, New YorkAges 18 years+ - NCT05695638Recruiting
Genetic tumor testing to find treatments for advanced cancer
This study looks at your tumor’s genetic information to help match you to targeted treatments when standard options are no longer working. You may be offered options based on results, with the goal of helping people with incurable, worsening cancer.
AalborgAges 18 years+ - NCT05696626RecruitingPhase 3
Test a new pill plus abemaciclib versus standard therapy
This Phase 3 study compares lasofoxifene plus abemaciclib versus fulvestrant plus abemaciclib for ER-positive, HER2-negative breast cancer that has an ESR1 mutation. It looks for better tumor control in people whose cancer has progressed on hormone therapy (an aromatase inhibitor) and who meet specific safety and testing requirements.
Scottsdale, ArizonaAges 18 years+ - NCT05697926Recruiting
Personalized immune T-cell therapy study for head and neck cancer
This study focuses on testing a personalized immune therapy (made from your tumor-fighting T cells) for people with head and neck cancer. It may help patients whose cancer is new and untreated or whose cancer has come back or is not responding to standard options.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05699213Recruiting
MRI and blood tests for lung nodules found on screening
This study looks at whether MRI scans and blood-related biomarkers can help better understand lung nodules found during routine lung cancer screening. It may help doctors decide which nodules need closer follow-up versus less intensive monitoring.
Los Angeles, CaliforniaAges 50 years+ - NCT05700721RecruitingPhase 2
Niraparib and dostarlimab for cancer with growing brain spots
This trial studies whether the medicines niraparib and dostarlimab can slow advanced cancers that have active, growing brain metastases. It is meant for people whose brain tumors can be measured on MRI and who have had at least one previous treatment.
Houston, TexasAges 18 years+ - NCT05704062Recruiting
Breast MRI during chemotherapy to measure treatment response
This study uses breast MRI scans to see whether neoadjuvant (before-surgery) chemotherapy is working. If you qualify, you’ll have MRI scans to help doctors understand how your breast cancer responds to standard treatment.
Iowa City, IowaAges 18 years+ - NCT05704530Recruiting
Liquid blood tests for early esophageal cancer
This trial studies how well “liquid biopsy” blood tests can work in people with newly diagnosed, operable esophageal cancer. It may help doctors monitor the cancer and guide treatment planning alongside standard care.
AntwerpAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,324 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.