Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,078 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT00006518Recruiting
Tissue samples from people with viral infections or cancer
This study collects tissue and blood samples from people who have or have been exposed to certain viruses (HIV, KSHV, HPV, EBV, or HTLV-1) or who have developed cancer or precancerous skin lesions. The samples help researchers understand how these viruses may lead to cancer.
Bethesda, MarylandAges 18–120 - NCT00923065Enrolling by invitation
NCI care and data study for patients and donors
This study helps collect information and provide certain clinical care and interventions for people who come to the National Cancer Institute (NCI) Clinical Center (CCR). It may be a fit if you need NCI-level evaluation or support because your condition is complex, or if you’re involved as a cellular therapy donor or certain family members needing genetic testing.
Bethesda, MarylandAges 4 weeks–120 years - NCT00026650Recruiting
Understanding Long-Term Effects After Radiation Therapy
This study follows patients who have received radiation therapy to learn about long-term health effects and how the disease progresses over time. By tracking your health over the years, researchers hope to better understand and help future patients manage side effects.
Bethesda, MarylandAges 18–120 - NCT04941716RecruitingPhase 2
Combination therapy for relapsed or refractory chronic lymphocytic leukemia
This trial tests two targeted drugs, acalabrutinib and venetoclax, taken together for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that has returned or not responded to previous treatment. The goal is to see if this combination helps control the disease and improves outcomes.
Seattle, WashingtonAges 18 years+ - NCT07008638RecruitingPhase 1/Phase 2
Treatment for newly diagnosed AML with a TP53 mutation
This study tests a combination of two drugs, bortezomib and CPX-351, for people with a specific type of acute myeloid leukemia (AML) that has a change in the TP53 gene. The purpose is to see if this combination is safe and effective.
Minneapolis, MinnesotaAges 18 years+ - NCT07042919RecruitingPhase 1/Phase 2
Zanzalintinib for advanced liver cancer after prior treatment
This trial tests a new pill called zanzalintinib for people with advanced liver cancer that has grown after earlier treatments. It aims to see if the drug can shrink tumors and help patients live longer.
Chicago, IllinoisAges 18 years+ - NCT06816459RecruitingEarly Phase 1
Sensory tests of cigarette flavors in daily adult smokers
This study tests how well you can smell different flavors in cigarettes. It will help researchers understand how flavor affects smoking, which may lead to better ways to help people cut back or quit.
Buffalo, New YorkAges 21 years+ - NCT07892027RecruitingPhase 2
Preventing brain side effects during car t-cell therapy
This study tests whether giving a drug called natalizumab before CAR T-cell therapy can lower the risk of a serious side effect that affects the brain and nervous system (called ICANS). It is for people with diffuse large B-cell lymphoma or mantle cell lymphoma that has come back or not responded to treatment.
Ann Arbor, MichiganAges 18 years+ - NCT05903950Recruiting
Clean air for better blood pressure
This study tests if using a special air filter in your home can lower your blood pressure. It is for people in Qatar with mild high blood pressure.
DohaAges 18–65 - NCT04107285Recruiting
Cognitive and brain changes in people getting CAR-T therapy
This study looks at how CAR-T therapy, a type of cancer treatment that uses your own immune cells, may affect your thinking and brain. By tracking these changes, doctors hope to better support patients during and after treatment.
New York, New YorkAges 18 years+ - NCT02984761Recruiting
Surgery or radiation for early-stage lung cancer
This study compares two standard treatments for early-stage non-small cell lung cancer: surgery to remove the tumor versus a precise type of radiation (stereotactic radiotherapy). The goal is to see which treatment is better for overall health and quality of life.
Long Beach, CaliforniaAges 18 years+ - NCT06644430Recruiting
Tumor ablation for lung spots in advanced liver cancer
This trial tests whether destroying a small number of lung tumors with ablation can help people with advanced liver cancer who are already on systemic therapy. Ablation uses heat or cold to target tumors directly, which may slow the cancer's growth and improve outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT06422806RecruitingPhase 3
Immunotherapy plus chemo for aggressive sarcoma
This trial compares a combination of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) versus chemotherapy alone for people with aggressive, poorly differentiated sarcomas that have spread or cannot be removed. The goal is to see if adding immunotherapy helps shrink tumors or slow their growth better than chemotherapy alone.
Phoenix, ArizonaAges 18 years+ - NCT07654257RecruitingPhase 2
Single radiation treatment after breast surgery
This trial tests a one-time radiation treatment given directly to the area where your breast cancer was removed. It aims to reduce the need for multiple radiation sessions and may be an option for certain patients with early-stage breast cancer.
Richmond, VirginiaAges 40–85 - NCT05675410RecruitingPhase 3
Testing two-drug treatment versus standard for Hodgkin lymphoma
This Phase 3 study compares today’s standard treatment for classic Hodgkin lymphoma with a new combination using brentuximab vedotin and nivolumab. The goal is to see which approach works better and is safe for newly diagnosed patients with early-stage disease.
Birmingham, AlabamaAges 5–60 - NCT06279013Recruiting
Phone check-ins to manage symptoms during oral cancer treatment
This study tests two ways of using telephone check-ins to help people manage side effects and emotional distress while taking oral anti-cancer pills at home. If you are starting or recently started an oral anti-cancer drug, you may be able to join.
Phoenix, ArizonaAges 18 years+ - NCT07672483RecruitingPhase 1
Gene therapy for solid tumors that returned after treatment
This trial tests a new type of gene therapy that uses your own immune cells (called myeloid cells) engineered to produce a protein (IL-12) to fight your cancer. It is for people with solid tumors that have not responded to standard treatments.
Bethesda, MarylandAges 18–120 - NCT07644559RecruitingPhase 2
Study of VS-7375 with cetuximab for advanced pancreatic cancer
This trial tests a new drug combination for people with a specific KRAS mutation in pancreatic cancer. It aims to see if the treatment can shrink tumors or slow the disease.
Los Angeles, CaliforniaAges 18 years+ - NCT06487481RecruitingPhase 1
Radiation before surgery for recurrent adrenal cancer
This trial tests whether giving radiation before surgery helps people with adrenal cancer that has come back after previous treatment. It aims to see if this approach can improve outcomes for patients who can have surgery at the NIH.
Bethesda, MarylandAges 18–120 - NCT05621291Recruiting
Sequencing test to guide care after CD19 CAR T in kids
This study checks a DNA-based lab test (next-generation sequencing, or NGS) to monitor B-cell recovery after CD19 CAR T treatment in children and young adults. The goal is to see whether the test can help guide management while looking for remission and safe recovery.
Los Angeles, CaliforniaAges 1–25 - NCT07252232RecruitingPhase 3
A pill to prevent pancreatic cancer recurrence after surgery
This trial tests an experimental daily pill, daraxonrasib, in people with pancreatic cancer that has been surgically removed. It’s for those who also had chemotherapy and have a specific DNA change called a RAS mutation. The goal is to see if the pill helps prevent the cancer from coming back.
Birmingham, AlabamaAges 18 years+ - NCT07472868RecruitingPhase 3
Comparing chemo combinations before surgery or watch-and-wait for rectal cancer
This trial compares two different chemotherapy combinations given before radiation or surgery for high-risk locally advanced rectal cancer. One arm is more intense, and the other is standard. The goal is to see which works better at shrinking the tumor and possibly avoiding surgery.
Arnhem, GelderlandAges 18 years+ - NCT07737132Recruiting
Nerve blocks for pain relief after breast removal surgery
This study compares two different types of nerve blocks (injections of numbing medicine) to see which works better for pain relief after breast removal surgery. If you are having a mastectomy, this trial might help reduce your pain after the operation.
Istanbul, UskudarAges 18–65 - NCT07135882RecruitingPhase 3
Radiotherapy for lung cancer that has spread
This trial tests whether giving radiotherapy to the main lung tumor, along with the usual medicines (like chemotherapy or immunotherapy), can help people with stage IV lung cancer. The goal is to see if adding this treatment helps control the cancer and improves how long patients live.
Blacktown, New South WalesAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,078 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.