Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04513808RecruitingPhase 3
Compare IV versus inhaled anesthesia for esophageal surgery
This trial tests whether using IV anesthesia (given through a vein) or inhaled anesthesia helps people live longer without their esophageal cancer coming back after surgery. You’d be randomly assigned to one anesthesia type as part of potentially curative surgery.
ShanghaiAges 18–90 - NCT04519151RecruitingPhase 2
Pembrolizumab plus lenvatinib for ovarian cancer that returned
This Phase 2 trial tests whether pembrolizumab plus lenvatinib can shrink ovarian cancer that has come back after platinum chemotherapy. You may be eligible if your cancer returned after a certain “time off” from prior treatment and you meet key health and safety requirements.
Ramat GanAges 18 years+ - NCT04516720Recruiting
Build a database of brain and spinal cord tumor cases
This study builds a large medical database of people with primary brain or spinal cord tumors treated at the Montpellier Cancer Institute. It may help researchers understand patterns of care and outcomes, which can guide future research and treatment decisions.
Montpellier, HeraultAges 18 years+ - NCT04528420Recruiting
Early treatment plan for head and neck skin cancer
This study tests an optimized plan for treating squamous cell cancer in the head and neck area using curative treatment that includes chemotherapy with cisplatin plus radiation after surgery. It may help doctors improve early management and outcomes for people eligible for this standard approach.
AmiensAges 18–75 - NCT04531696Recruiting
Post-death breast tissue donation study for cancer research
This trial invites adults with certain breast cancer conditions to donate tissue after death. Researchers hope the donated samples will help better understand cancer and improve future treatments.
LeuvenAges 18 years+ - NCT04534127Recruiting
DaRT radiation device for skin and mouth or superficial tumors
This trial tests a targeted radiation device (DaRT seeds) to treat certain cancers on the skin, in the mouth, or in superficial soft tissue. It may help when standard treatment (like surgery or regular radiation/chemo) hasn’t worked, isn’t safe, or isn’t wanted.
JerusalemAges 18 years+ - NCT04534543Recruiting
Imaging scans to personalize chemotherapy for liver spread of bowel cancer
This trial tests whether special liver imaging can help doctors choose or guide the best chemotherapy for people with liver metastases from gastrointestinal cancer. The study focuses on comparing imaging-based information with outcomes during common chemo treatments like CAPOX or FOLFOX.
AmsterdamAges 18 years+ - NCT04536220Recruiting
Blood-based tests to help diagnose pancreatic cancer
This study uses blood taken from a vein to build and check diagnostic models for pancreatic cancer. It may help doctors identify pancreatic cancer more accurately in people who have a suspected mass on imaging.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT04543071RecruitingPhase 2
Second-line-like immunotherapy and chemo for metastatic pancreatic cancer
This Phase 2 trial studies a combination of immunotherapy, a blood-vessel/immune signal blocker, and chemotherapy for people with metastatic pancreatic adenocarcinoma. It may help shrink tumors and improve control of the disease.
New York, New YorkAges 18 years+ - NCT04550104RecruitingPhase 1
Durvalumab with radiation for lung cancer patients
This trial tests adding durvalumab (an immune therapy) to a radiation treatment plan for people with non-small cell lung cancer (NSCLC) who can’t safely have chemotherapy at the same time or surgery first. It aims to improve cancer control after radiation by helping the immune system recognize and fight the tumor.
BelfastAges 18 years+ - NCT04564989Recruiting
Biomarker study for HPV-related throat cancer outcomes
This observational study checks how well a blood test for HPV DNA (and other tumor genetic markers) predicts outcomes in certain throat cancers. It may help doctors better track the disease and plan treatment, because the trial validates these lab signals against real-world results.
Rochester, MinnesotaAges 18 years+ - NCT04567706Recruiting
Melanoma tissue samples storage for future research
This study is about collecting and storing tissue samples from people affected by melanoma so researchers can use them for future studies. It may help speed up research, but it is mainly about sample storage rather than testing a new treatment.
Columbus, OhioAges Any age - NCT04571294Recruiting
Removing lymph nodes during Whipple surgery for pancreatic cancer
This study looks at removing certain lymph nodes near the aorta while doing a standard Whipple operation for pancreatic head cancer. The goal is to see whether this approach can improve how well doctors manage the cancer spread.
Rozzano, Italy/MilanAges 18 years+ - NCT04577014RecruitingPhase 1/Phase 2
Retifanlimab plus chemotherapy for advanced soft tissue sarcoma
This trial tests retifanlimab (an immunotherapy that helps your immune system recognize cancer) combined with gemcitabine and docetaxel chemotherapy. It’s for people with advanced soft tissue sarcoma that can’t be safely removed with surgery, aiming to shrink tumors and improve outcomes.
New York, New YorkAges 18 years+ - NCT04577599Recruiting
Mobile low-dose lung CT screening for ages 40–54
This study offers mobile low-dose CT scans to help find lung problems early in people at higher risk from smoking. You may be invited because of your age and smoking history, and the results may guide next steps with your care team.
Charlotte, North CarolinaAges 40–54 - NCT04585490RecruitingPhase 3
Testing a personalized add-on treatment after stage III lung cancer
This phase 3 trial tests whether tailoring the next (add-on) treatments can improve outcomes after standard chemoradiation and immunotherapy for stage III, unresectable (not operable) non-small cell lung cancer. It specifically looks at giving durvalumab plus an additional drug (tremelimumab) and possibly other consolidation chemotherapy based on a personalized plan.
Stanford, CaliforniaAges 18 years+ - NCT04587791RecruitingEarly Phase 1
Cannabidiol (CBD) for opioid use disorder and chronic pain
This early study tests whether CBD can reduce symptoms of chronic pain in people receiving opioid maintenance treatment for opioid use disorder. It also looks at safety and whether CBD can be added without causing major problems.
West Haven, ConnecticutAges 18–70 - NCT04588168Recruiting
MRI helps guide bladder cancer treatment planning
This trial uses special MRI scans to help doctors choose precise treatment for bladder cancer before and/or around surgery. It may help tailor therapy more accurately while you receive standard bladder cancer care.
Nanjing, JiangsuAges 18 years+ - NCT04591002RecruitingPhase 2
Osimertinib after lung cancer surgery to slow new lung spots
This trial studies osimertinib, a targeted medicine, after surgery to help stop lung cancer from growing or spreading. It’s for people with an early lung cancer that has EGFR mutations and leftover “ground-glass” lung spots in another area.
Seoul, KangnamguAges 30–75 - NCT04592003Recruiting
French study of colorectal ESD performed by expert centers
This study follows people who are having a colon or rectum procedure called ESD in expert hospital centers in France. It mainly aims to collect information about outcomes and safety; joining depends on consent.
AmiensAges 18 years+ - NCT04593589RecruitingPhase 1
Stem cell transplant to protect salivary function after oral cancer
This Phase 1 study tests whether transplanting stem cells into the submandibular gland can help restore saliva function after surgery and radiation for oral cavity squamous cell cancer. You may be considered because you recently had tumor removal and radiation aimed at the neck area, which can damage salivary glands.
GroningenAges 18 years+ - NCT04604522Recruiting
Study airway brushing in people with bronchiolitis obliterans
This study collects tiny airway samples during a planned bronchoscopy to better understand bronchiolitis obliterans (a long-term lung complication after transplant). Your samples may help researchers learn how the disease starts and changes over time.
Houston, TexasAges Any age - NCT04606030Recruiting
Tested lymph surgery for breast-cancer–related arm swelling
This trial studies a specialized lymph surgery (called VLNT, moving lymph tissue) to treat swelling in an arm caused by breast cancer treatment. It may help reduce lymphedema that doesn’t fully improve with compression and elevation.
Chicago, IllinoisAges 18–75 - NCT04604730Recruiting
Testing a protective stoma after bowel reconnection for infection
This study looks at whether creating a temporary “protective stoma” (an opening that diverts stool) after reconnecting the bowel can reduce complications for people with severe abdominal infection from a perforated diverticulitis. It’s for adults who had surgery to reconnect their colon right away.
Beauvais, BeauvaisAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,308 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.