Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04612075Recruiting
PET-MR scan study for head and neck squamous cancer
This study uses a combined PET/MR scan to better look at head and neck squamous cell cancer before or during treatment. It may help doctors see where the cancer is and how far it has spread, to support planning for curative radiation treatment.
TromsøAges 18 years+ - NCT04613570Recruiting
Follow-up endoscopy plan for early stomach changes
This study looks at how often and how intensely to do follow-up stomach camera exams (endoscopy) with small biopsies for people at risk of stomach cancer. It may help personalize your follow-up schedule based on your specific stomach findings.
PortoAges 45 years+ - NCT04614480RecruitingPhase 2
Genetic test on tumor to guide cancer treatment choices
This trial looks at the tumor’s DNA to help doctors choose the best next treatment for people with advanced cancer. It’s testing whether this “exome” genetic analysis can improve therapeutic decisions for newly treated metastatic or locally advanced solid tumors.
AmiensAges 18 years+ - NCT04614194RecruitingPhase 2
Blood and tumor markers to test response to abemaciclib
This trial studies how the immune system and other body signals in blood and tumor tissue relate to how well abemaciclib works before breast cancer surgery. The goal is to learn who benefits most from this medicine and why.
Dallas, TexasAges 18 years+ - NCT04615988Recruiting
Vitamin D levels and hormone side effects from immune cancer therapy
This study looks at whether your blood vitamin D level is linked to hormone-related side effects caused by immune checkpoint cancer drugs. It may help doctors better predict who is at risk and how to monitor patients during treatment.
New York, New YorkAges 18 years+ - NCT04617756RecruitingPhase 2
Durvalumab plus chemo before surgery for high-risk upper urinary tract cancer
This trial studies whether durvalumab (an immunotherapy) given with chemotherapy before surgery can improve outcomes for people with high-risk cancer in the kidney pelvis or ureter. It is mainly looking at safety and effectiveness in shrinking or controlling the cancer before treatment continues.
Paris, Paris Cx 20Ages 18 years+ - NCT04621435RecruitingPhase 1
PET imaging test for solid tumors using FAP-2286
This Phase 1 study tests a special imaging scan (using FAP-2286) to see solid tumors in people who have already been diagnosed. It may help doctors better detect where cancer is in the body and how to plan treatment.
San Francisco, CaliforniaAges 18 years+ - NCT04622462Recruiting
Testing a lab marker to predict oral cancer risk
This study looks at biopsy samples from mouth lesions that seem concerning, to see if a specific lab marker pattern can help predict whether oral cancer may be present or developing. It may help doctors sort which suspicious lesions need closer attention sooner.
Edmonton, AlbertaAges 15–90 - NCT04624373Recruiting
Test tumor DNA from breath biopsy samples
This study checks tiny pieces of DNA from a sample taken during a breathing-tube biopsy (EBUS-TBNA) to better identify certain lung cancer changes. It may help doctors learn more about the type of lung cancer and, in some cases, why targeted treatments stop working.
ToulouseAges 18–65 - NCT04623931RecruitingPhase 2
Chemo and radiation for IDH-wildtype glioma
This Phase 2 study tests a combination of chemotherapy and radiation after surgery for certain brain tumors that are “IDH wildtype.” It aims to control the tumor and improve outcomes for people with specific types of glioma or glioblastoma.
Houston, TexasAges 18 years+ - NCT04629326Recruiting
Imaging scan that targets PD-L1 in digestive cancer
This study tests an imaging method that looks for PD-L1 (a protein linked to some cancers) in solid tumors, including gastrointestinal cancers. It may help doctors better see where PD-L1 is in the body using a scan.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04630496Recruiting
Walk Test Before Lung Surgery for Older Adults
This study is looking at a “walk and movement” challenge for older adults preparing for thoracic (chest) surgery. It may help the team understand mobility and support safer care before surgery.
Boston, MassachusettsAges 65 years+ - NCT04631770Recruiting
Mediastinal node removal versus sparing nodes for early lung nodule
This trial compares two surgical approaches for people with a single small, noncancer-looking lung nodule (a GGN) that is diagnosed as very early lung cancer. It aims to see whether removing mediastinal lymph nodes—or leaving them alone—can lead to better outcomes with less harm.
Tianjin, Tianjin MunicipalityAges Any age - NCT04632654Recruiting
Video game exercise program to help head and neck cancer symptoms
This study tests a “motion-based video game” type exercise to help with moderate fatigue and/or pain in adults with head and neck cancer. It may help you feel better day to day while staying active at a low-to-moderate intensity.
Birmingham, AlabamaAges 18 years+ - NCT04638088Recruiting
Robot or standard surgery for prostate removal
This trial compares different ways of doing a radical prostatectomy (surgery to remove the prostate): robot-assisted laparoscopy, conventional laparoscopy, or open surgery. It may help improve which approach is best for people having planned prostate removal.
AgenAges 18 years+ - NCT04644952Recruiting
Study of robotic lung segment surgery outcomes
This study looks at people who had a lung surgery called a segmentectomy with robotic assistance in the past. It aims to understand how these surgeries are done over time and what outcomes result for patients.
Houston, TexasAges Any age - NCT04644289RecruitingPhase 2
Olaparib plus durvalumab for early testing in ovarian cancer
This study tests whether olaparib and durvalumab given around the time of diagnosis can help people with advanced ovarian cancer. It also strongly focuses on collecting tumor and blood samples to better understand who may benefit.
Mannheim, Baden-WurttembergAges 18 years+ - NCT04650919Recruiting
Rehabilitation graft after larynx removal for upper airway cancer
This trial tests a special “rehabilitation graft” used after total laryngectomy (complete larynx removal) for upper airway cancer. The goal is to improve recovery and function after surgery by using a graft designed to support healing and rehabilitation.
StrasbourgAges 18 years+ - NCT04652180Recruiting
Robot surgery versus open surgery for esophagus cancer
This trial compares robot-assisted surgery with the standard open chest operation to remove esophagus and nearby tissue. It may help you understand which approach works better and is safer for patients whose cancer can be surgically removed.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT04655066Recruiting
Questionnaire study for pelvic floor symptoms during cancer treatment
This study asks people with breast or gynecologic cancer who are receiving cancer treatment to complete a validated questionnaire about how their pelvic floor feels. The goal is to better understand pelvic floor function and symptoms during systemic (whole-body) cancer therapy, which may help future care.
WiesbadenAges 18 years+ - NCT04659616RecruitingPhase 1
Pemigatinib after standard chemo for newly diagnosed AML
This Phase 1 trial studies whether adding pemigatinib after standard “7+3” chemotherapy can improve outcomes in certain newly diagnosed acute myeloid leukemia (AML) patients. It aims to find a safe dose and see how well the drug works in a very specific AML genetic group.
Portland, OregonAges 18 years+ - NCT04665388Recruiting
Mapping immune responses in people with certain virus-related cancers
This study collects blood and/or tumor-related samples to map how your immune system recognizes cancer. It aims to better understand immune targets and immune cell types, which may help guide future cancer treatments for certain virus-related cancers.
Toronto, OntarioAges 18 years+ - NCT04666727Recruiting
Diet and gut microbiome study during screening colonoscopy
This study looks at how a person’s diet (vegetarian vs. omnivorous) affects the germs in the gut and related stool and tissue samples. You may be able to join if you’re getting a screening colonoscopy and meet lifestyle and medication requirements.
Houston, TexasAges 45 years+ - NCT04671667RecruitingPhase 2
Pembrolizumab vs chemo-radiation after surgery for recurrent head/neck cancer
This trial tests whether pembrolizumab (an immunotherapy drug) works better than the usual chemo plus radiation after surgery for cancer that has come back in the head and neck area. It may help reduce cancer returning or spreading by using your immune system, but eligibility depends on how the cancer came back and your prior treatments.
Birmingham, AlabamaAges 18–79
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,308 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.