Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06796543Recruiting
Radiation for young patients with sarcoma that has spread
This trial tests whether targeted radiation can help children and young adults with sarcoma that has spread to a few spots in the body. It's for those who are newly diagnosed (Stratum A) or whose sarcoma has come back or worsened (Stratum B).
Washington D.C., District of ColumbiaAges Up to 39 years - NCT07243002Recruiting
Patient outcomes with ribociclib or abemaciclib for early breast cancer
This study looks at how women and men with stage II or III HR+ HER2- breast cancer do when they start treatment with ribociclib or abemaciclib (combined with hormone therapy) after surgery. Researchers want to understand real-world experiences and results.
LondonAges 18 years+ - NCT07139977RecruitingPhase 2
Study of EV for recurrent endometrial cancer
This trial tests a drug called EV for people with recurrent endometrial cancer that has gotten worse after treatment. It may help if your cancer cells have a specific protein called nectin-4.
Milwaukee, WisconsinAges 18 years+ - NCT04934293Recruiting
Virtual reality support during proton radiation for children
This trial tests whether virtual reality (VR) can be used safely and comfortably for children receiving proton radiation. It aims to improve the experience of treatment by using a VR helmet during radiotherapy sessions.
NiceAges 7–18 - NCT04934540Recruiting
Bladder tumor surgery approach registry study
This study is for adults who have a bladder tumor and are having a standard kind of surgery through the urethra. Researchers will collect information about this “en bloc resection” approach to better understand outcomes and care for people with bladder tumors.
Hong KongAges 18 years+ - NCT04937309Recruiting
Vagus nerve stimulation for nausea from chemo
This trial tests a non-invasive device that stimulates a nerve in your ear to help prevent nausea caused by chemotherapy. It is for people with breast cancer who are about to start a specific type of chemo (anthracycline and cyclophosphamide).
BloisAges 18 years+ - NCT04939051RecruitingPhase 2
Obeticholic acid to prevent Barrett’s esophagus worsening
This Phase 2 trial tests whether obeticholic acid (a medicine) can help stop Barrett’s esophagus from getting worse. You must already be taking acid-suppressing medicine and have non-cancer Barrett’s changes, and the study checks safety and whether the lining improves or stays stable.
Kansas City, KansasAges 18 years+ - NCT04941274RecruitingPhase 1/Phase 2
Abemaciclib for Kaposi sarcoma in people with or without HIV
This Phase 1/2 study tests the medicine abemaciclib to shrink Kaposi sarcoma (KS) lesions and control the disease. It includes both people with HIV and people without HIV, and may help when KS has not responded well to prior treatment or when certain KS stages are present.
Bethesda, MarylandAges 18–99 - NCT04941716RecruitingPhase 2
Acalabrutinib plus venetoclax for hard-to-treat CLL/SLL
This Phase 2 trial studies whether combining acalabrutinib and venetoclax can shrink or control chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that has come back or did not respond to prior treatment. It may help by attacking the cancer using two different medicines together.
Seattle, WashingtonAges 18 years+ - NCT04944563Recruiting
Segmentectomy vs lobectomy for small middle-lung lung cancer
This trial compares two types of lung surgery for certain small lung cancers in the middle part of the lung: removing a segment (segmentectomy) versus removing a whole lobe (lobectomy). It aims to see which surgery works better while balancing cancer control and lung function.
Nanjing, JiangsuAges 18–75 - NCT04951817Recruiting
PSMA PET/CT scan to assess Ra-223 treatment in advanced prostate cancer
This trial studies whether a special whole-body scan (PSMA PET/CT) can help assess how well Ra-223 (a targeted treatment) may work in men with advanced prostate cancer that has spread to the bones. It may help doctors choose and plan Ra-223 treatment more effectively.
Taoyuan CityAges 40–85 - NCT04949737Recruiting
Study stomach bacteria and stomach cancer in Martinique adults
This study looks at how common Helicobacter pylori (a common stomach germ) is in adults with stomach cancer in Martinique, and how it relates to stomach cancer. It mainly involves answering questionnaires and allowing study details to be collected to better understand risk and patterns.
Fort-de-FranceAges 18 years+ - NCT04952272RecruitingPhase 1
Shots into the tumor to boost the immune system
This Phase 1 study tests an injection given directly into an advanced solid tumor to help the immune system better recognize and attack cancer. It may help people with advanced solid tumors, but the goal at this early stage is mainly to check safety and how the treatment works.
Guangzhou, GuangdongAges 18–80 - NCT04953897RecruitingPhase 1
Oral decitabine for cancer patients with kidney problems
This Phase 1 trial studies how an oral combination cancer medicine behaves in the body (dose handling and safety) in people with kidney impairment. It may help doctors learn the safest way to use this treatment when kidney function is reduced.
Houston, TexasAges 18 years+ - NCT04953910RecruitingPhase 1
Oral decitabine for cancers with liver problems
This Phase 1 trial studies how a pill form of decitabine/cedazuridine behaves in the body and how safe it is for people whose livers don’t work normally. It may help doctors better understand dosing and safety in patients with hepatic impairment.
Houston, TexasAges 18 years+ - NCT04954820RecruitingPhase 2
Second round Lutathera for intestinal NET after regrowth
This Phase 2 study looks at whether giving Lutathera again (a second round) can control an intestinal neuroendocrine tumor (NET) that came back or progressed after the first treatment. It mainly targets adults whose scan shows tumors still take up the right “target” signal and who previously benefited for at least 12 months.
AngersAges 18 years+ - NCT04956133Recruiting
Physical activity program for kids during cancer treatment
This trial tests whether a structured physical activity program can help children and teens feel better and stay active during cancer treatment or shortly after. It involves the child and a parent/caregiver for safety during sessions.
Calgary, AlbertaAges 5–18 - NCT04959175RecruitingPhase 1/Phase 2
Lower post-transplant drug doses for older or unfit patients
This trial tests whether giving a lower dose of cyclophosphamide after a bone marrow transplant can be safer for older or medically “unfit” patients, while still helping control blood cancers. It is designed for people who can’t tolerate the usual strongest transplant preparation.
Bethesda, MarylandAges 12–85 - NCT04959604Recruiting
Fluorescent dye mapping to find lymph nodes in colon cancer
This trial studies whether a fluorescent dye used during an exam can help doctors map (find) lymph nodes in colon cancer. It may help improve how surgeons plan treatment and decide what to remove.
HamburgAges 18–100 - NCT04960839Recruiting
Preventive radiation to the other breast after breast cancer surgery
This study looks at whether “preventive” radiation to your other (opposite) breast can lower the chance of future breast cancer in people at higher genetic risk. You must have had surgery for early-stage breast cancer and agree to avoid removing the other breast and ovaries.
Jiangxi, JiangxiAges 30–70 - NCT04962867RecruitingPhase 2
Targeting FGFR changes in advanced, hard-to-treat cancers
This Phase 2 study tests a treatment aimed at specific FGFR (a cancer-growth signal) changes found in your tumor. It may help people whose cancer has spread, cannot be removed, or has stopped responding to standard treatment.
Chuo-ku, Tokyo, JapanAges 20 years+ - NCT04968288Recruiting
Study of the natural course of KSHV-related Castleman disease
This study looks at how KSHV-associated multicentric Castleman disease naturally progresses over time, without necessarily testing a new treatment. It may help doctors better understand the disease and what changes to watch for, which could guide future care.
Bethesda, MarylandAges 18 years+ - NCT04969926Recruiting
Study of parathyroid problems in children and adults
This is an observational study that follows people who have or may develop parathyroid-related conditions. The goal is to better understand how these problems change over time and what patterns show up, which can help improve future care.
Bethesda, MarylandAges 6 months–100 years - NCT04969731RecruitingPhase 3
Immune cell therapy plus gemcitabine after pancreas surgery
This Phase 3 trial tests whether adding an immune cell therapy (Immuncell-LC) to the standard chemotherapy drug gemcitabine helps people with resectable pancreatic cancer after surgery. It aims to improve safety and outcomes like preventing the cancer from coming back.
Seoul, Daehak-ro, Jongno-guAges 19–80
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,308 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.