Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,052 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07207824RecruitingPhase 3
Study of a new drug for high-risk bladder cancer
This trial tests a combination of a drug (DV) and BCG immunotherapy for people with high-risk, early-stage bladder cancer that has not spread into the muscle. The cancer must show a specific protein called HER2 on its cells.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07210164Recruiting
Pre-surgery wellness program for gynecologic cancer surgery
This trial tests whether a pre-surgery wellness program (pre-habilitation) within an enhanced recovery protocol helps women recover better after surgery for endometrial, ovarian, or cervical cancer. It is designed for women who are having open abdominal surgery (laparotomy).
ThessalonikiAges 18–85 - NCT07210086RecruitingPhase 2
PET scans to guide radiation for limited metastatic prostate cancer
This trial uses a special PET scan (POSLUMA) before and after radiation to see if it helps treat prostate cancer that has spread to a few spots outside the pelvis. It's for men whose cancer still responds to hormone therapy and who have not had widespread spread.
Duarte, CaliforniaAges 18 years+ - NCT07204574RecruitingPhase 1/Phase 2
New drug combo for advanced colorectal cancer after first treatment
This trial tests a new drug combination for advanced colorectal cancer that has not gotten better with standard chemotherapy. It is for people whose tumors have normal RAS and BRAF genes, and it adds a new type of medicine (HCB101) to a common chemotherapy plus targeted therapy regimen.
TaoyuanAges 18 years+ - NCT07211386Recruiting
Nerve block for severe cancer-related abdominal pain
This study tests whether a nerve block, called an erector spinae plane block, can reduce severe abdominal pain in people with gastrointestinal cancer who come to the emergency room. If you have cancer in your digestive system and are in pain that isn't controlled, this trial may help.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06930378Recruiting
Breast skin feeling after DIEP flap reconstruction
This trial compares three surgical techniques to see which one best preserves or improves skin feeling after breast reconstruction with a DIEP flap (using your own tissue to rebuild the breast). You may join if you are having this type of reconstruction and do not have nerve problems or smoke.
Geneva, Canton of GenevaAges 18–80 - NCT05536128RecruitingPhase 2
Fulvestrant plus DNA damage drugs after CDK4/6 treatment failure
This Phase 2 trial studies whether combining fulvestrant with medicines that block DNA repair can help treat HR+/HER2- metastatic or inoperable breast cancer that has progressed after endocrine therapy plus a CDK4/6 inhibitor. It also aims to check the safety of this combination and see if it can control the cancer for longer.
SeoulAges 19 years+ - NCT05876676Recruiting
Test a cancer blood marker in people being checked for cancer
This study checks a “biomarker” (a measurable sign in your body, often from blood) in people who are being investigated for possible cancer in a specific body area. It may help researchers understand whether the marker can support or rule out cancer when no cancer has been confirmed yet.
AbergavennyAges 18 years+ - NCT06754930RecruitingPhase 1/Phase 2
Study of SHR-1826 combined with other treatments for lung cancer
This trial tests a new drug called SHR-1826 in combination with other anti-cancer therapies for people with non-small cell lung cancer (NSCLC). It aims to see if these combinations are safe and effective for patients who haven't been treated before or whose cancer has come back.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06751498Recruiting
Predicting kidney function after partial nephrectomy with AI
This trial uses a special computer model to predict how well your kidneys will work after surgery to remove part of a kidney (partial nephrectomy). It may help doctors plan better care for people with early-stage kidney tumors.
Nanjing, JiangsuAges 18–80 - NCT06923345RecruitingPhase 2
Modified long-course radiation and chemo with immunotherapy for rectal cancer
This trial tests a treatment plan involving radiation, chemotherapy, and an immunotherapy drug (a PD-1 inhibitor) for people with a specific type of high-risk rectal cancer. The goal is to see if this combination helps shrink the tumor before surgery.
Guangzhou, GuangdongAges 18–75 - NCT06933758Recruiting
Temple Health Chest Lung Screening Study
This study looks at how a hospital program can help people who are at risk for lung cancer get the proper screening and follow-up care. You may be eligible if you are a Temple patient and have had a low-dose CT scan for lung cancer screening.
Philadelphia, PennsylvaniaAges 50–80 - NCT06935448Recruiting
Recovery program for pancreatic cancer surgery
This trial tests a special recovery program called Enhanced Recovery After Surgery (ERAS) for people having planned open surgery for pancreatic cancer. The goal is to see if this program helps patients recover faster and with fewer complications after their operation.
LarissaAges 18 years+ - NCT07195994Recruiting
Study of an investigational product with or without semaglutide for blood sugar
This trial tests an investigational product to see how well it controls blood sugar in adults with prediabetes or type 2 diabetes. Some participants will also take the diabetes medication semaglutide to compare effects.
London, OntarioAges 18 years+ - NCT07197554RecruitingPhase 1
A study of an experimental drug for advanced solid tumors
This trial tests a new drug, ST-01156, designed to attack cancer cells by breaking down a protein called RBM39. It may be an option for people with advanced solid tumors that have not responded to other treatments.
Duarte, CaliforniaAges 16 years+ - NCT07195695RecruitingPhase 3
Zongertinib after surgery for HER2-mutated lung cancer
This trial tests a new pill, zongertinib, against standard of care for people with early-stage (II–IIIB) non-small cell lung cancer that has a specific HER2 mutation in the tyrosine kinase domain. The goal is to see if zongertinib can prevent the cancer from coming back after complete surgical removal.
Fresno, CaliforniaAges 18 years+ - NCT05518643Recruiting
Testing a stress-reducing recovery plan for pancreatic surgery patients
This trial tests how well a structured hospital recovery plan (called ERAS) works for people having pancreatic surgery. It looks at stress and recovery outcomes to see if patients may do better with this approach.
LarissaAges 18 years+ - NCT06111417Recruiting
Rapid BRCA1/2 test for newly diagnosed breast cancer patients
This study tests a new ultra-rapid genetic test for BRCA1/2 mutations in people recently diagnosed with breast cancer. It aims to see if the faster result helps doctors and patients make treatment decisions sooner.
DijonAges 18 years+ - NCT06925243RecruitingPhase 3
Apatinib, Sintilimab, and Chemo for Intestinal Gastric Cancer
This phase 3 trial tests adding the targeted drug apatinib to a standard combination of sintilimab (immunotherapy) and chemotherapy (SOX regimen) given before surgery for a specific type of stomach or gastroesophageal junction cancer (intestinal type, HER2-negative). The goal is to see if the three-drug combination works better than the two-drug combination in shrinking the tumor and improving outcomes before surgery.
Lanzhou, GansuAges 18–75 - NCT06926790RecruitingPhase 2
Immunotherapy before surgery for stage II-IIIA lung cancer
This trial tests whether two immunotherapy drugs (nivolumab and ipilimumab) given before surgery can help treat non-small cell lung cancer that is stage II to IIIA. It's for people whose tumors are removable and who haven't had prior cancer treatment.
GuangzhouAges 18–80 - NCT04737889RecruitingPhase 2
Rituximab plus lenalidomide, methotrexate, and temozolomide for brain lymphoma
This Phase 2 study tests a combination treatment to shrink primary central nervous system lymphoma that starts in the brain, spinal cord, meninges, or eye. It may help patients who have not had anti-cancer treatment yet, but it requires specific cancer type and health conditions.
Zhengzhou, HenanAges 18–70 - NCT06938373Recruiting
A test for breast cancer patients with possible depression
This study tests a new detection method for depression in people with breast cancer. It uses samples like blood, stool, and saliva to find a link between breast cancer and depression.
Changsha, HunanAges 18–80 - NCT05209620RecruitingPhase 2
Orelabrutinib plus pemetrexed for lymphoma in the brain
This Phase 2 trial tests a combination medicine (orelabrutinib with pemetrexed) to treat lymphoma that has returned or is not responding, specifically in the brain or spinal fluid. If you qualify, the goal is to shrink measurable tumors and improve control of central nervous system lymphoma.
Zhengzhou, HenanAges 18–75 - NCT07193641RecruitingPhase 2
Lattice radiotherapy with standard care for slow-growing lung cancer
This trial tests whether adding a special radiotherapy technique called lattice radiotherapy to your usual cancer treatment can help control NSCLC that has started to grow in a few new spots. If you have up to 5 growing tumors and at least one measures 4.5 cm or larger, this study might be an option.
Hangzhou, ZhejiangAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,052 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.