Clinical trials · Boston, MA
Cancer clinical trials in Boston
We’re tracking 801 recruiting cancer studies with a site in or near Boston — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT06661720RecruitingPhase 3
Tivozanib and pembrolizumab after kidney cancer surgery
This trial is testing if adding the targeted therapy tivozanib to the immunotherapy drug pembrolizumab (Keytruda) can help prevent kidney cancer from coming back after all known tumors have been removed by surgery.
Boston, MassachusettsAges 18 years+ - NCT07735624RecruitingPhase 2
Immunotherapy before surgery for early rectal cancer
This trial tests a combination of two immunotherapy drugs (botensilimab and balstilimab) given before surgery for early-stage rectal cancer that is MSS/pMMR. The goal is to see if this treatment can shrink the tumor and improve outcomes compared to standard care.
Boston, MassachusettsAges 18 years+ - NCT03029325Recruiting
Test genes in lung cancer tissue and samples
This study looks at genetic (DNA) and molecular (cell-level) information related to lung cancer to better understand the disease. You may be invited if you have a confirmed primary lung cancer diagnosis, or if you are healthy with no cancer.
Boston, MassachusettsAges 18 years+ - NCT06997029RecruitingPhase 1
Study of BMS-986500 for advanced solid tumors
This trial tests a new drug called BMS-986500, alone or with other treatments, for people with advanced solid tumors that cannot be removed by surgery or have spread. It aims to see if the drug is safe and effective.
Boston, MassachusettsAges 18 years+ - NCT06997185Recruiting
Study on explaining cancer drug benefits and risks
This study looks at how to explain the benefits and risks of new cancer drugs in a way that is easier to understand. It helps researchers learn how to communicate better with patients like you.
Boston, MassachusettsAges 18 years+ - NCT04045470Recruiting
Skin-device test to find drugs for T-cell lymphoma lesions
This trial tests a tiny device placed directly into skin lymphoma spots to help identify which “candidate” drugs could work. It’s mainly aimed at people with measurable skin involvement from T-cell lymphoma, after they stop certain treatments for a set time.
Boston, MassachusettsAges 18 years+ - NCT06748222RecruitingPhase 3
Online mindfulness program for breast cancer survivors
This trial tests a 6-week online mindfulness program to help breast cancer survivors manage mild to moderate depression. You may qualify if you finished active treatment within the last 5 years and can use a digital device.
Boston, MassachusettsAges 18–50 - NCT07000084RecruitingPhase 3
Testing gemcitabine with BCG for returning bladder cancer
This trial tests whether adding a chemotherapy drug called gemcitabine to the usual BCG therapy can help prevent bladder cancer from coming back again. If you have had BCG before and your cancer returned, this study might offer a more effective treatment option.
Boston, MassachusettsAges 18 years+ - NCT07002034RecruitingPhase 2
RE104 for adjustment disorder related to cancer or other serious illnesses
This trial is testing a new medication (RE104) for people who have adjustment disorder with depressed mood or anxiety because of a serious medical condition like cancer, ALS, MS, Parkinson's, or lung fibrosis. It's a study to see if the drug is safe and reduces symptoms.
Boston, MassachusettsAges 18–80 - NCT05765500RecruitingPhase 2
Relugolix vs leuprolide to improve prostate cancer quality of life
This Phase 2 study compares two medicines that lower testosterone—relugolix tablets versus leuprolide injections—to see which better improves quality of life. It’s for people with prostate cancer who are starting hormone treatment and have not used similar testosterone-lowering drugs before.
Boston, MassachusettsAges 18 years+ - NCT06369155RecruitingPhase 2
Azenosertib for recurrent uterine serous cancer
This trial is testing an oral drug called azenosertib for a type of uterine cancer that has come back or spread. It aims to see if blocking a DNA repair pathway can shrink tumors or slow their growth.
Boston, MassachusettsAges 18 years+ - NCT07227415RecruitingPhase 1/Phase 2
Study of a new drug for advanced kidney cancer
This trial tests a new drug, PF-08634404, alone or with other cancer treatments, for adults with advanced kidney cancer that has not been treated before. It aims to see if the drug can help shrink tumors or stop them from growing.
Boston, MassachusettsAges 18 years+ - NCT05176483RecruitingPhase 1
New drug combinations for advanced solid tumors
This trial tests a new drug called zanzalintinib, which may slow or shrink various types of advanced cancer. It is given together with other cancer treatments, and the study is looking at many different cancers including kidney, prostate, bladder, lung, liver, and more.
Boston, MassachusettsAges 18 years+ - NCT06774963RecruitingPhase 1
Study of LNCB74 for advanced solid tumors
This trial tests a new drug called LNCB74 for people with advanced solid tumors that have not responded to other treatments. It aims to see if the drug is safe and effective.
Boston, MassachusettsAges 18 years+ - NCT05779423RecruitingPhase 2
Freezing tumor plus two immunotherapies for advanced melanoma
This trial tests whether combining a local treatment that freezes a tumor (cryoablation) with two immune “checkpoint” medicines (ipilimumab and nivolumab) can better control unresectable melanoma. It may help when melanoma has grown after prior immune therapy.
Boston, MassachusettsAges 18 years+ - NCT05797168RecruitingPhase 1/Phase 2
Early study drug for advanced solid tumors, alone or with another drug
This Phase 1/2 study tests a new AstraZeneca cancer drug (AZD5335) to see how safely it can be given and how well it works in people with advanced solid tumors. You may get it alone or with another treatment, and you’ll need to provide tumor information (sometimes including a biopsy) for study planning.
Boston, MassachusettsAges 18–130 - NCT07222215RecruitingPhase 2
Capacitabine with or without elacestrant for ER+ breast cancer
This trial tests if adding a new oral targeted therapy (elacestrant) to standard chemotherapy (capecitabine) works better than chemotherapy alone for people with a specific type of advanced breast cancer that is hormone-sensitive (ER-positive) and has stopped responding to hormone therapy.
Boston, MassachusettsAges 18 years+ - NCT06787612RecruitingPhase 2
New combination for platinum-resistant ovarian cancer
This study tests a new combination treatment (ubamatamab plus another drug) for people with ovarian cancer that no longer responds to platinum chemotherapy. It could be an option if your cancer has kept growing despite prior treatment.
Boston, MassachusettsAges 18 years+ - NCT07024615RecruitingPhase 1
Study of ASP2138 before surgery for pancreatic cancer
This study tests an experimental drug, ASP2138, given before surgery for pancreatic cancer that is still removable. After surgery, you will receive standard chemotherapy. The goal is to see if adding ASP2138 before surgery helps improve outcomes.
Boston, MassachusettsAges 18 years+ - NCT06377852RecruitingPhase 3
Dosing study for older adults with advanced breast cancer
This trial studies how well different doses of CDK4/6 inhibitors (palbociclib or ribociclib) work in people aged 65 or older with HR+/HER2- metastatic breast cancer. It aims to find the best starting dose to balance effectiveness and side effects.
Boston, MassachusettsAges 65 years+ - NCT07216560RecruitingPhase 1/Phase 2
Testing a new drug for advanced stomach or bowel cancer
This trial tests a new drug called 7MW4911 for people with advanced gastrointestinal cancer that has not responded to standard treatments. The drug is designed to target and attack cancer cells, and doctors will check if it is safe and effective.
Boston, MassachusettsAges 18 years+ - NCT06579417Recruiting
Testing a faster MRI for prostate cancer detection
This trial is testing a new, faster type of MRI scan (called biparametric MRI) to see if it can detect prostate cancer as well as the standard scan. It may help you avoid a longer scan and possibly reduce the need for contrast dye.
Boston, MassachusettsAges 18 years+ - NCT06577987RecruitingPhase 1
Study of CID-078 for advanced solid tumors
This trial tests an experimental drug called CID-078 for people with advanced solid tumors that have stopped responding to other treatments. It aims to find the right dose and see if the drug can shrink tumors.
Boston, MassachusettsAges 12 years+ - NCT06380751RecruitingPhase 3
New targeted therapy for BRCA/PALB2-mutated HR+ breast cancer
This trial tests a new combination of targeted therapies (saruparib plus camizestrant or hormone therapy) against standard treatments for people with a specific type of advanced breast cancer. It may be a good option if you have a BRCA1, BRCA2, or PALB2 gene mutation and have not yet had treatment for your advanced disease.
Boston, MassachusettsAges 18 years+
Hear when a new Cancer trial opens near Boston, MA
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Cancer trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting cancer studies listed above.
- Dana-Farber Cancer Institute · 12 studies
- Massachusetts General Hospital · 6 studies
- Brigham and Women's Hospital · 5 studies
- Dana-Farber Cancer Institute at Foxborough · 3 studies
- Lahey Hospital and Medical Center · 3 studies
- Lahey Medical Center-Peabody · 3 studies
- Addison Gilbert Hospital · 2 studies
- Beverly Hospital · 2 studies
What taking part in a cancer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting cancer studies in Massachusetts.
Common questions
- Are there cancer clinical trials near Boston?
- Yes. We're currently tracking 801 recruiting cancer studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cancer study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cancer studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.