Clinical trials · Boston, MA
Cancer clinical trials in Boston
We’re tracking 801 recruiting cancer studies with a site in or near Boston — including Early Phase 1, Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT06686394RecruitingPhase 1/Phase 2
Patritumab deruxtecan combinations for advanced HER2-positive breast cancer
This trial tests a new drug, patritumab deruxtecan, combined with other anti-cancer drugs for people with HER2-positive breast cancer that has spread or cannot be removed by surgery. It aims to see if these combinations can shrink tumors or slow cancer growth.
Boston, MassachusettsAges 18 years+ - NCT06690775RecruitingPhase 2
Study of a new drug for platinum-resistant ovarian cancer
This trial tests an investigational drug called TORL-1-23 for people with ovarian cancer that has stopped responding to platinum chemotherapy. It aims to see if the drug can help shrink or control the cancer.
Boston, MassachusettsAges 18 years+ - NCT06902376RecruitingPhase 1
XL092 and cemiplimab for advanced thyroid cancer without BRAF mutation
This trial tests a combination of two drugs, XL092 and cemiplimab, for people with a rare and aggressive type of thyroid cancer called anaplastic thyroid cancer. The drugs aim to shrink tumors before surgery and help the immune system fight the cancer.
Boston, MassachusettsAges 18 years+ - NCT06253871RecruitingPhase 1
Study of IAM1363 for HER2 Cancers
This trial tests a new oral drug called IAM1363 for people with HER2-altered cancers that have stopped responding to previous treatments. The goal is to see if the drug is safe and how well it works against these cancers.
Boston, MassachusettsAges 18 years+ - NCT06672146RecruitingPhase 2
New treatments for AML with an IDH2 mutation
This trial tests new treatments for people with newly diagnosed acute myeloid leukemia (AML) that has a change in the IDH2 gene. It aims to find a better option for those who cannot have standard high-dose chemotherapy.
Boston, MassachusettsAges 18 years+ - NCT04794322Recruiting
Testing uterine fluid to help detect ovarian cancer
This study checks whether a sample of fluid from the uterus (uterine lavage) can help detect ovarian or fallopian tube cancer. You may join if you are having certain gynecologic surgeries or, in a smaller group, you have a BRCA1/2 mutation.
Boston, MassachusettsAges 30 years+ - NCT06274047RecruitingPhase 3
Hormone Therapy Timing for Prostate Cancer After Surgery
This trial compares two ways of giving hormone therapy (apalutamide) along with radiation after prostate removal surgery. It aims to see which approach helps maintain quality of life while controlling cancer.
Boston, MassachusettsAges 18 years+ - NCT06468618Recruiting
Sleep and stress program for kids getting stem cell transplant
This study tests a program to help children ages 9–17 who are getting a stem cell transplant at Boston Children's Hospital. It aims to improve sleep and reduce stress for both the child and their family.
Boston, MassachusettsAges 9–17 - NCT06533826RecruitingPhase 2
Testing two antibody drugs for HER2-low breast cancer
This trial tests two antibody-drug conjugates (Enhertu and Datroway) for breast cancer that is HER2-low or HER2-0. It aims to find the best treatment sequence for people whose cancer has stopped responding to prior therapy.
Boston, MassachusettsAges 18 years+ - NCT06651580Recruiting
Gene study for kids with pancreas problems
This study collects samples like blood or tissue from children with pancreatitis to look for gene changes that might raise their risk. It helps doctors learn more about why some children get pancreas inflammation.
Boston, MassachusettsAges Up to 17 years - NCT07130786RecruitingPhase 2
Preventing seizures with medication for brain tumors in movement area
This study tests whether giving a seizure medication (levetiracetam) to people with brain tumors in the movement area can prevent seizures. It compares taking the medication to not taking it, starting before any seizure occurs.
Boston, MassachusettsAges 18 years+ - NCT06549465RecruitingPhase 2
Ac-225 rosopatamab for PSMA-positive castration-resistant prostate cancer
This trial tests a radioactive drug (Ac-225 rosopatamab tetraxetan) that targets a protein called PSMA on prostate cancer cells. It is for patients whose cancer has stopped responding to hormone therapy and has spread to other parts of the body.
Boston, MassachusettsAges 18 years+ - NCT06655246RecruitingPhase 1
Ziftomenib and imatinib for advanced GIST
This trial tests a new drug, ziftomenib, combined with imatinib for people with advanced or spreading gastrointestinal stromal tumors (GIST) that have a KIT mutation. It may help if your GIST has gotten worse while on imatinib.
Boston, MassachusettsAges 18 years+ - NCT06661720RecruitingPhase 3
Tivozanib and pembrolizumab after kidney cancer surgery
This trial is testing if adding the targeted therapy tivozanib to the immunotherapy drug pembrolizumab (Keytruda) can help prevent kidney cancer from coming back after all known tumors have been removed by surgery.
Boston, MassachusettsAges 18 years+ - NCT05098132RecruitingPhase 1/Phase 2
STK-012 drug for advanced lung cancer and other tumors
This trial tests STK-012 (alone and with other treatments) in people with advanced cancers, especially non-small cell lung cancer. It may help by activating the immune system to recognize and fight the tumor.
Boston, MassachusettsAges 18 years+ - NCT04545957Recruiting
Radiation planning study using MRI for adults with cancer
This trial tests a “master protocol” approach to use MRI (a detailed body scan) to help plan radiation treatment for people with cancer. It may help doctors customize radiation more accurately, depending on your specific cancer type.
Boston, MassachusettsAges 18 years+ - NCT04363164RecruitingPhase 2
Testosterone then enzalutamide to stop prostate cancer spread
This Phase 2 trial tests whether giving testosterone first, then enzalutamide (a prostate cancer hormone-blocking pill), can slow or prevent worsening metastatic prostate cancer. It is designed for men whose cancer progressed despite ongoing hormone-suppression treatment.
Boston, MassachusettsAges 18–90 - NCT06664151RecruitingEarly Phase 1
Flu vaccine injected into skin cancer before surgery
This study tests whether injecting the seasonal flu vaccine directly into a skin cancer tumor can help the immune system attack it. You would receive the injection before your scheduled surgery to remove the cancer.
Boston, MassachusettsAges 18 years+ - NCT05168930RecruitingPhase 2
Zanubrutinib plus venetoclax for relapsed CLL or SLL
This Phase 2 study tests how well zanubrutinib (a targeted pill) combined with venetoclax (another targeted pill) works for adults with CLL/SLL that came back or progressed after prior treatment. It may help by stopping cancer cells through two different pathways, aiming to shrink disease and improve blood counts.
Boston, MassachusettsAges 18 years+ - NCT06667908RecruitingPhase 2
Study of a drug with chemoradiation for stage 3 lung cancer
This trial tests a new drug, JNJ-90301900, given together with standard chemotherapy and radiation, followed by maintenance immunotherapy (durvalumab) for people with stage 3 non-small cell lung cancer that cannot be surgically removed. The goal is to see if adding this drug improves outcomes.
Boston, MassachusettsAges 18 years+ - NCT05216432RecruitingPhase 1
RLY-2608 for PIK3CA-mutant advanced solid tumors and breast cancer
This early study (Phase 1) tests RLY-2608, a targeted cancer drug for tumors with a PIK3CA mutation. It studies the drug alone and combined with hormone therapy (and sometimes CDK4/6 or CDK4 medicines) to see safety, dose, and whether it can shrink tumors.
Boston, MassachusettsAges 18 years+ - NCT06677190RecruitingPhase 2
Belzutifan for Recurrent Clear Cell Gynecologic Cancer
This study tests a daily pill called belzutifan for people with a rare type of gynecologic cancer (clear cell carcinoma) that has come back or not gone away after standard treatments. The drug works by targeting a protein that helps tumors grow when oxygen levels are low.
Boston, MassachusettsAges 18 years+ - NCT05287451Recruiting
Tube removal now, ovaries later for high cancer-risk women
This study looks at the safety of removing your fallopian tubes first (RRS) and delaying ovary removal (oophorectomy) to lower cancer risk. It focuses on women who carry certain inherited gene changes, and may help avoid earlier menopause for some people.
Boston, MassachusettsAges 18 years+ - NCT05381597RecruitingPhase 2/Phase 3
Skin cream treatment for small early non-melanoma skin cancers
This study tests whether 5-fluorouracil and calcipotriene (medicines used on the skin) can treat certain small, early skin cancers or pre-cancers without surgery. It’s for specific types and locations of lesions and aims to see how well the treatment works and how safe it is.
Boston, MassachusettsAges 18 years+
Hear when a new Cancer trial opens near Boston, MA
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Cancer trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting cancer studies listed above.
- Dana-Farber Cancer Institute · 15 studies
- Massachusetts General Hospital · 6 studies
- Beth Israel Deaconess Medical Center · 4 studies
- Brigham and Women's Hospital · 3 studies
- Tufts Medical Center · 2 studies
- Addison Gilbert Hospital
- Beverly Hospital
- Boston Children's Hospital
What taking part in a cancer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting cancer studies in Massachusetts.
Common questions
- Are there cancer clinical trials near Boston?
- Yes. We're currently tracking 801 recruiting cancer studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cancer study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cancer studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.