Clinical trials · Columbus, OH
Cancer clinical trials in Columbus
We’re tracking 415 recruiting cancer studies with a site in or near Columbus — including Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Columbus
- NCT03866382RecruitingPhase 2
Immunotherapy plus a targeted drug for rare genitourinary tumors
This Phase 2 study tests whether nivolumab and ipilimumab (immunotherapy drugs) plus cabozantinib (a targeted anti-cancer drug) can shrink or control rare cancers of the urinary/reproductive system that have spread. It may help by boosting the immune system and blocking cancer growth signals at the same time.
Columbus, OhioAges 18 years+ - NCT07198074RecruitingPhase 3
Testing Avastin added to chemo plus Keytruda for certain endometrial cancer
This study tests adding Avastin (bevacizumab) to the standard combination of chemotherapy (carboplatin and paclitaxel) plus immunotherapy (Keytruda) for advanced or recurrent endometrial cancer with a specific genetic makeup (pMMR and TP53 mutation). The goal is to see if adding Avastin helps shrink tumors or slow their growth.
Columbus, OhioAges 18 years+ - NCT03998202Recruiting
Study of chemotherapy side effects in older colorectal cancer patients
This study looks at how chemotherapy and immunotherapy affect the body in older adults with colorectal cancer, especially early side effects. It may help researchers understand why some people lose strength and how to better predict and manage treatment toxicity.
Columbus, OhioAges 60 years+ - NCT06746012Recruiting
Health app study for colorectal cancer survivors and their caregivers
This study tests a mobile health program to help colorectal cancer survivors and their family caregivers stick to healthy lifestyle habits. It's for survivors who are at least 6 months past treatment and have a smartphone.
Columbus, OhioAges 18 years+ - NCT07346092Recruiting
Health beliefs and social behaviors about nicotine pouches
This study looks at how graduate students at Ohio State University perceive and use oral nicotine pouches. The goal is to create better ways to communicate the addictive risks of these products.
Columbus, OhioAges 21 years+ - NCT07795411Recruiting
Study of blood and tissue in small cell lung cancer
This study looks at blood and tissue samples from people with small cell lung cancer that has returned. The goal is to learn more about the cancer and how to better treat it.
Columbus, OhioAges 18 years+ - NCT01120353Recruiting
Childhood cancer survivors study to understand long-term health
This study follows people who survived certain childhood cancers to learn what long-term health effects may happen after treatment. It also compares survivors with siblings to help researchers understand differences that may be related to cancer or treatment.
Columbus, OhioAges Any age - NCT01042379RecruitingPhase 2
Adaptive drug trial for newly diagnosed breast cancer
This study tests personalized, changing treatment plans (given before surgery) to find better options for your specific breast tumor. You may be asked for extra breast-tissue testing to help match you with the most suitable study drug(s).
Columbus, OhioAges 18 years+ - NCT07431281RecruitingPhase 3
New drug combo for advanced stomach cancer with CLDN18.2
This trial tests a new drug combination for people with advanced stomach cancer that has not been treated before. It looks at two groups: one with PD-L1 (a protein that helps decide if immunotherapy works), and one without. The treatment includes an antibody-drug conjugate (Sonesitatug Vedotin) plus standard chemotherapy, with or without an immunotherapy drug.
Columbus, OhioAges 18 years+ - NCT07216534Recruiting
Virtual reality streetscape study for psychosocial response
This study uses virtual reality to show different versions of your neighborhood to see how it affects your feelings and well-being. You will attend a two-hour visit at Ohio State University.
Columbus, OhioAges 18 years+ - NCT05624918RecruitingPhase 2
Testing a tumor-treatment device plus chemotherapy for pancreatic cancer
This trial studies NovoTTF-200T(P), a portable treatment device, combined with standard chemotherapy (gemcitabine and nab-paclitaxel) for people with resectable pancreatic adenocarcinoma. It aims to improve treatment results by trying this combination before surgery.
Columbus, OhioAges 18 years+ - NCT01473784Recruiting
Robot-assisted mouth and throat surgery for head and neck tumors
This trial studies using a robot-assisted operation through the mouth to diagnose or treat certain non-cancer (benign) and cancer (malignant) tumors in the head and neck. It may help some people avoid more invasive surgery by using an approach that reaches the throat and voice box area through the mouth.
Columbus, OhioAges 18 years+ - NCT02090530Recruiting
Precision testing of tumor tissue for advanced cancers
This study uses advanced DNA testing on tumor samples to help match cancer treatments more precisely. It may help researchers learn which cancer changes are driving your tumor and how they relate to treatment choices.
Columbus, OhioAges 18 years+ - NCT06764875RecruitingPhase 3
New drug combo for HER2-positive stomach cancer
This trial tests a new immunotherapy called rilvegostomig combined with standard chemotherapy and a targeted therapy (trastuzumab deruxtecan) for people with advanced HER2-positive stomach or gastroesophageal junction cancer that has not been treated before.
Columbus, OhioAges 18 years+ - NCT05058651RecruitingPhase 2/Phase 3
Atezolizumab plus chemo for advanced neuroendocrine cancer outside the lung
This trial tests whether adding an immunotherapy drug called atezolizumab to standard chemotherapy helps people with advanced neuroendocrine carcinoma (a rare and aggressive cancer) that started outside the lung. The goal is to see if the combination works better than chemo alone.
Columbus, OhioAges 18 years+ - NCT05773274RecruitingPhase 2
Retreating with 177Lu-DOTATATE radiation versus usual treatment
This trial tests whether repeating a targeted radioactive treatment (177Lu-DOTATATE) works better than standard options in people with metastatic gastroenteropancreatic neuroendocrine tumors. It may help by controlling tumor growth after the first round of this therapy stops working.
Columbus, OhioAges 18 years+ - NCT03678025RecruitingPhase 3
Standard treatment for metastatic prostate cancer, with or without local treatment
This Phase 3 trial studies whether using the usual medicines for metastatic prostate cancer, plus a definitive local treatment to the prostate, improves outcomes. It may help determine if treating the prostate directly can benefit people whose cancer has not worsened after initial hormone-based treatment.
Columbus, OhioAges 18 years+ - NCT06060613RecruitingPhase 1/Phase 2
Engineered immune cells for advanced melanoma or lung cancer
This trial tests a new treatment called OBX-115, which uses a patient's own immune cells that are modified in a lab to better fight cancer. It is for people with advanced melanoma or non-small cell lung cancer that has not responded to standard treatments.
Columbus, OhioAges 18 years+ - NCT07437950RecruitingPhase 2
Comparing treatment lengths for venetoclax in older adults with newly diagnosed acute myeloid leukemia
This study tests whether a shorter or longer course of the drug venetoclax works better for older adults with a type of blood cancer called acute myeloid leukemia (AML) who are not healthy enough for intensive chemotherapy. The goal is to find the best treatment duration to control the cancer while reducing side effects.
Columbus, OhioAges 60 years+ - NCT06643884RecruitingPhase 2
Study of eye treatment for cancer that has spread to the eye
This trial tests a new way to treat cancer that has spread to the back of the eye (choroid). The treatment is given directly into the eye, which may help control the tumor and preserve vision.
Columbus, OhioAges 18 years+ - NCT03937635RecruitingPhase 3
Lenalidomide and dexamethasone, with or without daratumumab
This phase 3 trial studies whether lenalidomide plus dexamethasone can prevent or delay progression of “high-risk smoldering” multiple myeloma, and whether adding daratumumab improves outcomes. It’s meant for people who are not yet showing symptoms, but whose lab and scan results suggest higher risk.
Columbus, OhioAges 18 years+ - NCT06064097RecruitingPhase 2
Nivolumab plus chemo for young people with nasopharyngeal cancer
This trial tests combining the immunotherapy drug nivolumab with standard chemotherapy to treat newly diagnosed nasopharyngeal cancer in children and young adults. The goal is to see if adding this immune-boosting medicine can help shrink tumors and prevent the cancer from coming back.
Columbus, OhioAges Up to 21 years - NCT04165798Recruiting
Pembrolizumab with or without chemotherapy for stage IV lung cancer
This trial tests whether pembrolizumab alone, or pembrolizumab plus chemotherapy, can treat stage IV non-small cell lung cancer. It may help shrink tumors and improve outcomes by boosting the immune system, with or without added chemotherapy.
Columbus, OhioAges 18 years+ - NCT02402244Recruiting
Caring registry study for children and young people with cancer
This study keeps a careful record of children, teens, and young adults with cancer (and some related growths) and may follow them over time. It helps researchers better track outcomes and future contact so care can improve.
Columbus, OhioAges Up to 25 years
Hear when a new Cancer trial opens near Columbus, OH
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Cancer trials in other cities
Where these studies are running near Columbus
Institutions with a site for the recruiting cancer studies listed above.
- The Ohio State University · 14 studies
- Adena Regional Medical Center · 3 studies
- Columbus Oncology and Hematology Associates Inc · 3 studies
- Doctors Hospital · 3 studies
- Dublin Methodist Hospital · 3 studies
- Grady Memorial Hospital · 3 studies
- Grant Medical Center · 3 studies
- Knox Community Hospital · 3 studies
What taking part in a cancer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting cancer studies in Ohio.
Common questions
- Are there cancer clinical trials near Columbus?
- Yes. We're currently tracking 415 recruiting cancer studies with a site near Columbus, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cancer study near Columbus?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Columbus to take part?
- Not necessarily. These studies have a site near Columbus, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cancer studies open near Columbus regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.