Clinical trials · Ohio
Cancer clinical trials in Ohio
We’re tracking 794 recruiting cancer studies with a site in Ohio — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Ohio
- NCT06513962RecruitingPhase 3
Triptorelin to protect ovaries in young women with cancer
This study tests whether a medicine called triptorelin can protect the ovaries in young women and teens receiving strong chemotherapy for cancer. If you are newly diagnosed with a cancer (other than breast cancer) and are about to get certain chemotherapy drugs, this trial may help preserve your fertility.
Akron, OhioAges Up to 39 years - NCT06496256Recruiting
Barrigel gel for radiation after prostate removal
This trial tests a gel placed in the rectum during radiation therapy to protect healthy tissue after prostate removal. It is for men whose prostate cancer has come back (PSA rise) and who need radiation to the prostate bed.
Cleveland, OhioAges 18 years+ - NCT06511141Recruiting
Nerve stimulation for men with overactive bladder
This study tests a nerve stimulation device placed near the tailbone to help men with overactive bladder symptoms. If you have bothersome urinary urgency or frequency, this treatment may offer relief without drugs.
Cleveland, OhioAges 18 years+ - NCT06500065Recruiting
Testing a new PET scan for soft tissue sarcoma
This study uses a special PET/CT scan (68Ga-DOTATATE) to see if it can better find soft tissue sarcomas. You will also have a standard PET/CT scan for comparison, and the results may help guide your treatment.
Columbus, OhioAges 18 years+ - NCT06492122RecruitingPhase 1
Study of a radioactive drug for advanced prostate cancer
This trial tests a new radioactive treatment, [225Ac]Ac-FL-020, for men with metastatic castration-resistant prostate cancer (mCRPC) that has gotten worse despite other treatments. It's for those who have had at least one prior hormone therapy or chemotherapy.
Cleveland, OhioAges 18 years+ - NCT06489301Recruiting
Laser treatment for skin rejuvenation during tummy tuck
This study tests a laser treatment to see if it can help rejuvenate skin taken during tummy tuck surgery. If you are having a tummy tuck and meet the requirements, you may be able to join.
Fairborn, OhioAges 18 years+ - NCT06465316RecruitingPhase 1
Testing teclistamab with iberdomide for relapsed or refractory multiple myeloma
This trial tests a new combination of two drugs (teclistamab and iberdomide) for people with multiple myeloma that has come back or stopped responding to standard treatments. The goal is to see how well this combination works and whether it can help control the disease.
Columbus, OhioAges 18 years+ - NCT06476808RecruitingPhase 1
Testing a new drug for advanced solid tumors
This trial tests an investigational drug (BMS-986463) in people with advanced solid tumors. It aims to find a safe dose and see if it helps shrink or control the cancer. You must be well enough to do daily activities and have a tumor that can be biopsied before treatment starts.
Columbus, OhioAges 18 years+ - NCT06472765Enrolling by invitation
Study of the Vaginal Ecosystem in Healthy Women
This study looks at the natural balance of bacteria and other factors in the vagina of healthy women. It aims to learn more about what a healthy vaginal ecosystem looks like.
Mayfield Heights, OhioAges 18–89 - NCT06470971RecruitingPhase 2
Siltuximab to prevent severe side effects during immunotherapy rechallenge
This trial tests if siltuximab can prevent severe immune-related side effects when patients restart immunotherapy (anti-PD-1/PD-L1) after previous severe side effects. It aims to make rechallenge safer for people with advanced cancer.
Columbus, OhioAges 18 years+ - NCT06448351Recruiting
Changing nicotine in e-cigarettes to reduce harm
This study tests how changing the amount of nicotine in e-cigarettes affects people's behavior. It looks at two groups: young adults who already vape and older adult smokers who want to try vaping, to see if different nicotine levels can help reduce smoking or make vaping safer.
Columbus, OhioAges 21–65 - NCT06430788RecruitingPhase 2
Emapalumab for children with severe aplastic anemia
This trial tests whether a medication called emapalumab can help children with severe aplastic anemia, a condition where the bone marrow stops making enough blood cells. It combines emapalumab with standard immune-suppressing therapy to try to improve blood cell counts.
Cincinnati, OhioAges birth–25 years - NCT06428721Recruiting
Can laser treatment prevent skin spots in older adults?
This study tests if a laser treatment on your forearms can prevent precancerous spots (actinic keratoses) from developing in older adults with fair skin. You would receive the laser on one arm and a sham treatment on the other, and your skin will be monitored.
Fairborn, OhioAges 60 years+ - NCT06423573Recruiting
Skin cancer risk in epidermolysis bullosa patients using Filsuvez
This study tracks anyone with dystrophic or junctional epidermolysis bullosa who is using Filsuvez gel to see how often skin cancers appear. It is designed to understand the long-term safety of the treatment.
Cincinnati, OhioAges Any age - NCT06418204Recruiting
Cannabis use among cancer patients in community clinics
This study looks at how cancer patients use cannabis (marijuana) and cannabis products to manage symptoms during chemotherapy or immunotherapy. The goal is to learn about the benefits and risks so doctors can better guide patients.
Beavercreek, OhioAges 18 years+ - NCT06393374RecruitingPhase 3
Study of a new drug combination for residual TNBC after initial treatment
This trial tests a new combination of two drugs (sacituzumab tirumotecan and pembrolizumab) compared to standard chemotherapy for people with triple-negative breast cancer that did not fully respond to initial treatment. It aims to see if this combination helps prevent cancer from coming back.
Canton, OhioAges 18 years+ - NCT06385080RecruitingPhase 1/Phase 2
Study of amivantamab for head and neck cancer
This trial tests a drug called amivantamab, either alone or with other treatments, for people with head and neck cancer that has spread or come back. The goal is to see if the drug can help shrink tumors or control the cancer.
Cleveland, OhioAges 18 years+ - NCT06377852RecruitingPhase 3
CDK4/6 inhibitor dosing study for older adults with metastatic breast cancer
This study tests two targeted therapy drugs, palbociclib and ribociclib, combined with hormone therapy for people aged 60 or older with hormone receptor-positive, HER2-negative metastatic breast cancer. The goal is to see how well this treatment works and to gather information that may help improve dosing for older adults.
Cincinnati, OhioAges 60 years+ - NCT06353386RecruitingPhase 1/Phase 2
Opevesostat combinations for advanced prostate cancer
This study tests a new drug called opevesostat, alone or combined with other treatments, for men with advanced prostate cancer that has spread and stopped responding to hormone therapy. It aims to see if it can help control the cancer.
Cleveland, OhioAges 18 years+ - NCT06357533RecruitingPhase 3
New drug combo for advanced lung cancer with high PD-L1
This trial tests a new two-drug combination (Dato-DXd and an immunotherapy called rilvegostomig) as the first treatment for people with advanced non-squamous lung cancer who have high PD-L1 levels. The goal is to see if this combination works better than current standard options.
Toledo, OhioAges 18 years+ - NCT06357845Recruiting
East Palestine chemical exposure and genetic change study
This study looks at whether the chemical spill in East Palestine in 2023 caused changes in people's genes. It involves giving a blood or saliva sample to measure any tiny genetic changes linked to the exposure. It helps researchers understand long-term health risks.
Cleveland, OhioAges 18 years+ - NCT06337318RecruitingPhase 3
Comparing two drugs for low-tumor burden follicular lymphoma
This trial compares a standard drug called rituximab to a newer medicine called mosunetuzumab for people with a slow-growing type of lymphoma that is not causing many symptoms. The goal is to see if mosunetuzumab works better and has fewer side effects.
Avon, OhioAges 18 years+ - NCT06311214RecruitingPhase 2
Personalized ADC therapy for advanced solid tumors
This trial tests personalized antibody-drug conjugates (ADCs) for advanced solid tumors. It looks for specific proteins on your tumor cells to match you with a treatment that targets them directly.
Columbus, OhioAges 18 years+ - NCT06317649RecruitingPhase 2
Venetoclax with hypomethylating agents for older or unfit adults with FLT3-mutated AML
This trial tests a combination of medicines (venetoclax and a hypomethylating agent) for people with acute myeloid leukemia (AML) who have a FLT3 mutation. It may be an option for older adults or those who cannot tolerate intensive chemotherapy.
Cleveland, OhioAges 18 years+
Cancer trials by city in Ohio
Where these studies are running in Ohio
Institutions with a site for the recruiting cancer studies listed above.
- The Ohio State University · 7 studies
- Case Western Reserve University · 2 studies
- Armes Family Cancer Center
- Atrium Medical Center
- Blanchard Valley Hospital
- Case Western Reserve University, Case Comprehensive Cancer Center
- Children's Hospital Medical Center of Akron
- Cincinnati Children's
What taking part in a cancer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Cancer trials in other states
Common questions
- Are there cancer clinical trials in Ohio?
- Yes. We're currently tracking 794 recruiting cancer studies with a site in Ohio, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cancer study in Ohio?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Ohio to take part?
- Not necessarily. These studies have a site in Ohio, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cancer studies open in Ohio regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.