Clinical trials
Cancer clinical trials
Below are recruiting cancer clinical trials, each written for real people, not researchers. We’re tracking 13,118 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04631770Recruiting
Mediastinal node removal versus sparing nodes for early lung nodule
This trial compares two surgical approaches for people with a single small, noncancer-looking lung nodule (a GGN) that is diagnosed as very early lung cancer. It aims to see whether removing mediastinal lymph nodes—or leaving them alone—can lead to better outcomes with less harm.
Tianjin, Tianjin MunicipalityAges Any age - NCT04632654Recruiting
Video game exercise program to help head and neck cancer symptoms
This study tests a “motion-based video game” type exercise to help with moderate fatigue and/or pain in adults with head and neck cancer. It may help you feel better day to day while staying active at a low-to-moderate intensity.
Birmingham, AlabamaAges 18 years+ - NCT04638088Recruiting
Robot or standard surgery for prostate removal
This trial compares different ways of doing a radical prostatectomy (surgery to remove the prostate): robot-assisted laparoscopy, conventional laparoscopy, or open surgery. It may help improve which approach is best for people having planned prostate removal.
AgenAges 18 years+ - NCT04644952Recruiting
Study of robotic lung segment surgery outcomes
This study looks at people who had a lung surgery called a segmentectomy with robotic assistance in the past. It aims to understand how these surgeries are done over time and what outcomes result for patients.
Houston, TexasAges Any age - NCT04644289RecruitingPhase 2
Olaparib plus durvalumab for early testing in ovarian cancer
This study tests whether olaparib and durvalumab given around the time of diagnosis can help people with advanced ovarian cancer. It also strongly focuses on collecting tumor and blood samples to better understand who may benefit.
Mannheim, Baden-WurttembergAges 18 years+ - NCT04650919Recruiting
Rehabilitation graft after larynx removal for upper airway cancer
This trial tests a special “rehabilitation graft” used after total laryngectomy (complete larynx removal) for upper airway cancer. The goal is to improve recovery and function after surgery by using a graft designed to support healing and rehabilitation.
StrasbourgAges 18 years+ - NCT04652180Recruiting
Robot surgery versus open surgery for esophagus cancer
This trial compares robot-assisted surgery with the standard open chest operation to remove esophagus and nearby tissue. It may help you understand which approach works better and is safer for patients whose cancer can be surgically removed.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT04655066Recruiting
Questionnaire study for pelvic floor symptoms during cancer treatment
This study asks people with breast or gynecologic cancer who are receiving cancer treatment to complete a validated questionnaire about how their pelvic floor feels. The goal is to better understand pelvic floor function and symptoms during systemic (whole-body) cancer therapy, which may help future care.
WiesbadenAges 18 years+ - NCT04659616RecruitingPhase 1
Pemigatinib after standard chemo for newly diagnosed AML
This Phase 1 trial studies whether adding pemigatinib after standard “7+3” chemotherapy can improve outcomes in certain newly diagnosed acute myeloid leukemia (AML) patients. It aims to find a safe dose and see how well the drug works in a very specific AML genetic group.
Portland, OregonAges 18 years+ - NCT04665388Recruiting
Mapping immune responses in people with certain virus-related cancers
This study collects blood and/or tumor-related samples to map how your immune system recognizes cancer. It aims to better understand immune targets and immune cell types, which may help guide future cancer treatments for certain virus-related cancers.
Toronto, OntarioAges 18 years+ - NCT04666727Recruiting
Diet and gut microbiome study during screening colonoscopy
This study looks at how a person’s diet (vegetarian vs. omnivorous) affects the germs in the gut and related stool and tissue samples. You may be able to join if you’re getting a screening colonoscopy and meet lifestyle and medication requirements.
Houston, TexasAges 45 years+ - NCT04671667RecruitingPhase 2
Pembrolizumab vs chemo-radiation after surgery for recurrent head/neck cancer
This trial tests whether pembrolizumab (an immunotherapy drug) works better than the usual chemo plus radiation after surgery for cancer that has come back in the head and neck area. It may help reduce cancer returning or spreading by using your immune system, but eligibility depends on how the cancer came back and your prior treatments.
Birmingham, AlabamaAges 18–79 - NCT04677205Recruiting
Tumor-to-lymph-node study after lung cancer surgery
This study looks at molecular (biologic) signals in the tumor and nearby lymph nodes after curative surgery for stage IIIA lung cancer. It may help doctors better understand the disease and improve future treatment planning.
BordeauxAges 18 years+ - NCT04678401RecruitingPhase 1
Trial tests transplant using a half-matched donor for high-risk leukemia
This Phase 1 trial tests a special bone marrow transplant using a related “half-matched” donor (haploidentical), without a specific immune-suppressing medicine (“IS-free”). It’s for adults with certain high-risk AML or MDS to see if this approach can improve control of the disease while tracking safety.
Boston, MassachusettsAges 18–75 - NCT04680442RecruitingPhase 2
Keeping HER2 therapy when your heart function is weaker
This trial studies whether it’s safe to continue HER2-targeted breast cancer treatment (like trastuzumab, pertuzumab, or T-DM1) even when heart function (left ventricle) is reduced. It may help people avoid stopping a helpful cancer medicine because of heart concerns.
Porto Alegre, Rio Grande do SulAges Any age - NCT04683315RecruitingPhase 2
Pancreatic cancer biopsy-guided chemo before surgery
This trial uses a special gene test on fluid taken from an endoscopic ultrasound (EUS) biopsy to help choose chemotherapy before surgery for pancreas cancer. It aims to see if this approach improves outcomes by matching treatment to the tumor’s RNA pattern.
Scottsdale, ArizonaAges 18 years+ - NCT04686305RecruitingPhase 1
Test drug T-DXd plus immunotherapy, with or without chemotherapy for HER2+ lung cancer
This Phase 1 study tests the safety (and early effectiveness) of T-DXd combined with immunotherapy, sometimes also with chemotherapy, in people with advanced lung cancer that is HER2-positive. It may help if standard options have been limited or your tumor does not have certain genetic changes that already have targeted treatments.
Duarte, CaliforniaAges 18 years+ - NCT04689048RecruitingPhase 1
Testing a brain scan tracer for large, staged brain metastases
This Phase 1 study tests an injected radioactive tracer (18F-fluciclovine) to improve how doctors image and assess large brain metastases. It may help guide treatment when you’re receiving staged stereotactic radiosurgery (focused radiation in steps).
Miami, FloridaAges 18 years+ - NCT04690972Recruiting
Collection of blood and tissue samples for liver disease research
This study builds a research library of biological samples (like tissue and blood) from people with chronic liver disease. It aims to create better lab and preclinical models of tumors and long-term liver problems, which may help future treatments.
StrasbourgAges 18 years+ - NCT04690374Recruiting
Registry to Track Health Information in Desmoplastic Tumor
This registry collects health information from people diagnosed with desmoplastic small round cell tumor. Your information helps doctors and researchers better understand the illness over time.
New York, New YorkAges Any age - NCT04693468RecruitingPhase 1
Testing three combinations for advanced solid tumors with gene defects
This Phase 1 trial tests whether adding specific medicines (talazoparib plus another drug) can help people with advanced or metastatic solid tumors that have certain gene or tumor marker changes. It also aims to find safer, workable doses and see how well these combinations work in different tumor groups.
Houston, TexasAges 18 years+ - NCT04699292Recruiting
Registry study for local treatment in soft tissue sarcoma
This registry collects coded information about adults with a specific soft tissue sarcoma (MLS) to better understand how local treatments help. If you qualify, you don’t necessarily receive a new drug in this study—your data is used to improve future care.
AmsterdamAges 18 years+ - NCT04701853Recruiting
Exercise training after permanent stoma surgery
This trial looks at a specific exercise program after planned surgery to create a permanent stoma (an opening for stool). The goal is to see whether the training helps people recover and function better after surgery.
GothenburgAges Any age - NCT04706481Recruiting
Use of stored, de-identified samples for research
This trial is for people who already agreed to let researchers use their stored biological samples and medical information that has been removed of personal identifiers. It may help future studies by allowing researchers to analyze existing samples without using new samples from you.
Hong KongAges Any age
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Common questions
- Are there clinical trials for cancer?
- Yes. Clin2 currently lists 13,118 recruiting cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.