Clinical trials
Cancer clinical trials
Below are recruiting cancer clinical trials, each written for real people, not researchers. We’re tracking 12,855 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05700461RecruitingPhase 1
Testing a new implant drug delivery device for kidney cancer
This early-phase study tests a new small implant (“IMD”) that can deliver a drug for people with kidney cancer going to surgery. If you qualify, you would get the implant placed through the skin and later have it removed during your operation, along with extra lab checks and genetic testing.
Boston, MassachusettsAges 18 years+ - NCT05679557Recruiting
Assessing frailty before bladder surgery to improve recovery
This trial tests whether a thorough “geriatric assessment” (a health check focused on older adults) can help you be better prepared for bladder removal surgery. It may guide supportive care before and around surgery to improve safety and recovery.
OdenseAges 65 years+ - NCT05704647RecruitingPhase 2
Nivolumab plus relatlimab for melanoma in the brain
This Phase 2 study tests whether nivolumab plus relatlimab can shrink or control melanoma that has spread to the brain. It may help by boosting the immune system to attack the cancer, including melanoma in brain areas that can’t be treated with prior focused radiation.
Houston, TexasAges 18 years+ - NCT05676450Recruiting
Test blood DNA to find lymphoma changes and leftover disease
This study checks a blood test that looks for small DNA fragments (“cell-free DNA”) to find cancer changes that could guide treatment in diffuse large B-cell lymphoma. It also looks for “minimal residual disease,” meaning tiny amounts of lymphoma that may remain after treatment, and whether this test works across community cancer centers in Texas.
Houston, TexasAges 18 years+ - NCT05674396RecruitingPhase 2
Short-course radiation to ease symptoms from head and neck cancer
This Phase 2 trial tests a specific, shorter type of focused radiation to help relieve symptoms from head and neck squamous cell carcinoma. It compares two radiation timing/planning approaches to see which better improves comfort and quality of life.
Houston, TexasAges 18 years+ - NCT05687084Recruiting
Uterine manipulator vs no manipulator in endometrial cancer surgery
This trial compares using a surgical “uterine manipulator” device versus not using it during endometrial cancer surgery. It may help clarify which approach is safer and works better during planned hysterectomy.
Cuneo, ItalyAges 18–100 - NCT05556928Recruiting
Cancer and aging study for adults with blood cancers
This study builds a registry to learn how aging and “resilience” relate to outcomes in people with blood cancers. You may be asked to complete questionnaires during UAB visits, which can help researchers better understand needs in older adults.
Birmingham, AlabamaAges 50 years+ - NCT05665361RecruitingPhase 1/Phase 2
Testing palbociclib plus sasanlimab for advanced kidney cancers
This study tests a combination of two medicines—palbociclib and sasanlimab—in people with advanced clear cell or papillary kidney cancer. It’s mainly designed to check safety (and early signs of how well the treatment may work) in these cancer types.
Bethesda, MarylandAges 18–100 - NCT05663502Recruiting
Donate blood and tissue samples for HIV-related cancer research
This study collects blood and tissue samples to help researchers learn more about cancers related to HIV/AIDS. You may be able to join if you’re 18+ and have HIV and a cancer diagnosis, or (if HIV-negative) a certain cancer that is closely linked to AIDS-related cancers.
La Jolla, CaliforniaAges 18 years+ - NCT05642611RecruitingPhase 3
Cooling and compression for nerve protection during chemotherapy
This study tests whether using cooling and/or compression on the arms or legs can prevent nerve damage that can happen from certain chemotherapy drugs. If you get eligible chemo soon, this may help lower the chance of painful numbness or tingling during treatment.
Birmingham, AlabamaAges 18 years+ - NCT05671822RecruitingPhase 2
Study of targeted drugs for HER2-positive advanced stomach cancer
This Phase 2 trial tests whether SHR-A1811—given with other medicines—works safely and effectively for people with advanced stomach or gastroesophageal junction cancer that has high HER2. It may help shrink tumors or slow cancer growth, especially if previous treatment didn’t work.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05656794RecruitingPhase 2
Radiation after treatment for prostate cancer that has spread
This trial studies whether adding a targeted course of radiation to the prostate area after initial systemic treatment can improve outcomes for people with metastatic prostate cancer. It may help control the cancer by treating remaining disease after medicines have started working.
Toronto, OntarioAges 18–100 - NCT05653388Recruiting
Study biomarker testing in metastatic leiomyosarcoma
This trial looks at lab markers (biomarkers) in tumor samples from people with leiomyosarcoma that has spread or can’t be fully removed. It also enrolls people who are receiving certain first-line chemotherapy, and your results may help guide future treatment decisions.
Santa Monica, CaliforniaAges Any age - NCT05649852Recruiting
Testing how socio-aesthetic care may reduce anxiety during chemotherapy
This study looks at whether “socio-aesthetic” care (support that combines social and beauty/wellbeing elements) can lessen anxiety in people starting chemotherapy. It is designed for patients who are new to chemotherapy and can complete French questionnaires.
ValenceAges 18 years+ - NCT05643859Recruiting
Fiber supplement study for bowel health and gut bacteria
This study tests whether adding a dietary fiber supplement can change the bacteria in your colon (gut microbiome). You may be asked to take the fiber supplement during evaluation for a non-cancer rectal condition.
Portland, OregonAges 18 years+ - NCT05643014Recruiting
Study of chemical exposure in firefighters’ urine
This observational study looks at how common environmental chemicals may build up in firefighters, measured with urine samples before and after exposure. It may help researchers understand potential health risks in this job—even though you won’t receive study medicine.
Minneapolis, MinnesotaAges 18 years+ - NCT05641831RecruitingPhase 2
Canakinumab to prevent clonal blood count problems turning into cancer
This Phase 2 study tests canakinumab to help stop high-risk clonal cytopenias of unknown significance (CCUS) from progressing into a blood cancer. If you have persistent low blood counts and specific genetic features, this treatment may lower the chance of progression.
Miami, FloridaAges 18 years+ - NCT05655494Recruiting
Helping underrepresented people find cancer clinical trials
This study tests an approach to help people from groups historically underrepresented in cancer trials learn about and connect to clinical trials. It may help you get easier, more personal ways to be contacted about research options.
Gainesville, FloridaAges 18–100 - NCT05646576Recruiting
Palliative care support during blood cancer cell therapy
This trial studies whether adding palliative care (comfort-focused care to reduce stress and symptoms) helps people during adoptive cell therapy for blood cancers. It may help improve quality of life while you’re receiving the therapy.
Boston, MassachusettsAges 18 years+ - NCT05645718RecruitingPhase 2
Chemo plus targeted antibodies for relapsed childhood B-ALL
This Phase 2 study tests a combination treatment for children, teens, or young adults whose B-cell acute lymphoblastic leukemia (B-ALL) has come back or did not respond to initial therapy. It may help patients who cannot safely receive certain standard medicines like anthracyclines or who cannot tolerate PEG-asparaginase.
Houston, TexasAges 1–25 - NCT05669846RecruitingPhase 2
FMT plus pembrolizumab for advanced lung cancer after prior treatment
This Phase 2 trial studies whether adding fecal microbiome transplant (FMT) to pembrolizumab can help people with advanced, PD-L1–positive non-small cell lung cancer that has returned or progressed after anti–PD-1/PD-L1 therapy. You may be asked to give new tumor tissue and undergo gut procedures, because the study aims to change gut bacteria to boost the immune response.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05655949RecruitingPhase 2
Y-90 radiation plus immunotherapy and chemo for bile duct cancer
This trial studies whether combining Y-90 liver radiation with an immunotherapy drug (durvalumab) and chemo (gemcitabine and cisplatin) can better control locally advanced or metastatic intrahepatic cholangiocarcinoma (bile duct cancer in the liver). It may help shrink tumors and slow disease growth, depending on how well the treatment works for your cancer type and overall health.
Boston, MassachusettsAges 18 years+ - NCT05647564Recruiting
PET/CT scan to study why prostate cancer resists treatment
This study uses a PET/CT scan to learn how and why prostate cancer becomes resistant to treatment. It may help researchers better match future therapy choices for people whose prostate cancer is progressing.
Madison, WisconsinAges 18 years+ - NCT05672108RecruitingPhase 2
Chemo delivered into lung tumors using a catheter
This trial studies a treatment that delivers chemotherapy directly to lung tumors by placing a catheter into lung blood vessels. It may help people with lung cancer or lung metastases that are growing despite standard treatment, or who cannot tolerate it.
Duarte, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for cancer?
- Yes. Clin2 currently lists 12,855 recruiting cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.